5) questions with correct answers
What are the two categories of corticosteroids? Correct Answer-
Glucocorticoids and mineralocorticoids
Where are corticosteroids produced? Correct Answer-In the adrenal
cortex.
What are the three layers of the adrenal cortex from outside to inside?
What type of product is formed in each? Correct Answer-Zona
glomerulosa- mineralocorticoids
Zona fasciculata- Glucocorticoids
Zona reticularis- Adrenal androgens
What type of hormones glucocorticoids? What does this mean as far as
solubility? Correct Answer-They are steroid hormones meaning they are
fat soluble.
What are some examples of glucocorticoids? Correct Answer-
Corticosterone and cortisone.
What is cortisone? How does it become active? Correct Answer-
Cortisone is an inactive metabolite of cortisol and needs to be converted
to cortisol in the liver to have any effect.
, What is corticosterone? Correct Answer-A weak glucocorticoid mostly
being converted to aldosterone.
Can glucocorticoids be stored for quick release? Correct Answer-No,
they must be synthesized as needed and the rate of release depends on
how fast it is synthesized.
What stimulates the synthesis of glucocorticoids? Correct Answer-
Adrenocorticotropic hormone (ACTH)
What causes cortisol release? Correct Answer-Response to stressors
both physical and mental.
What is the trend of cortisol levels in regards to time of day? Correct
Answer-Spike and are highest in the morning while diminishing at night
and during early morning hours.
What does cortisol require for transport? Why? Correct Answer-It is
lipid soluble so it must be attached to a protein carrier to stabilize.
What proteins are responsible for carrying cortisol? How much is
unbound in the blood? Correct Answer-Transcortin and albumin. How
much remains unbound in the blood?
What must occur for cortisol to enter and impact a target cell? Correct
Answer-It must detach from the carrier protein.