Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton | 9780323796309 | | Chapter 1-48 | All Chapters with Answers and Rationals

TestBankForClayton’sBasicPharmacologyforNurses19thEdition
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By Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton
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Complete
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,Chapter 01: Drug Definitions, Standards, and Information Sources
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Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
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MULTIPLE CHOICE n




1. Which name identifies a drug listed bythe US Food and
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Drug Administration (FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C n


The official name is the name under which a drug is listed
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by the FDA. The brand name, or trademark, is the name
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given to a drug by its manufacturer. The nonproprietary, or
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generic, name is provided by the United States Adopted
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Names Council.
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DIF: Cognitive Level: Knowledge REF: p. 9 n n n n


OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care
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Environment TOP: Nursing Process Step: Assessment
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Patient Education
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2. Whichsource contains information specific to nutritional supplements?
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a. USPDictionary of USAN &International Drug Names n n n n n


b. Natural Medicines Comprehensive Database n n n


c. United States Pharmacopoeia/National Formulary (USPNF)
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d. DrugInteraction Facts n n




ANS: C n


UnitedStates Pharmacopoeia/National Formulary contains information specific to nutritional
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supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
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names, pronunciation guide, and possible future FDA approved drugs; it does not include
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nutritional supplements. Natural Medicines Comprehensive Database contains
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evidence-based information on herbal medicines and herbal combination products; it does not
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include information specific to nutritional supplements. Drug Interaction Facts contains
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comprehensive information on drug interaction facts; it does not include nutritional
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supplements.
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DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3 n n n n n


NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Assessment CON: Nutrition |Patient Education
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3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
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a. Drug Facts and Comparisons n n n

,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
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Edition
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b. DrugInteraction Facts n n


c. Handbook on Injectable Drugs n n n


d. Martindale—The Complete Drug Reference n n n




ANS: A n


Drug Facts and Comparisons contains drug monographs that describe all drugs in a
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therapeutic class. Monographs are formatted as tables to allow comparison ofsimilar
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nproducts, brand names, manufacturers, cost indices, and available dosage forms
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nOnline version is available.
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DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 n n n n n n


OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity n n n n n n


TOP: Nursing Process Step: Assessment CON: Safety |Patient Education |Clinical Judgment
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4. Which drug reference contains monographs about virtuallyeverysingle-entitydrug available
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in the United States and describes therapeutic uses of drugs, including approved and
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nunapproved uses? n


a. Martindale: The Complete Drug Reference n n n n


b. AHFS Drug Information n n


c. DrugReference n


d. DrugFacts and Comparisons n n n




ANS: B n


AHFS Drug Information contains monographs about virtually every single-entity drug
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available in the United States and describes therapeutic uses ofdrugs, including approved and
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unapproved uses.
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DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 n n n n n n


OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity n n n n n n


TOP: Nursing Process Step: Planning CON: Safety |Patient Education |Clinical Judgment
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5. Which online drug reference makes available to healthcare providers and the public a
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nstandard, comprehensive, up-to-date look up and downloadable resource about medicines?
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a. AmericanDrug Index n n


b. American Hospital Formulary n n


c. DailyMed
d. Drug Reference n




ANS: C n


DailyMed makes available to healthcare providers and the public a standard, comprehensive,
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up-to-date look up and downloadable resource about medicines. The American Drug Index is
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not appropriate for patient use. The American Hospital Formulary is not appropriate for
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patient use. The drug reference is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: 3 n n n n n n n


NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Implementation
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CON: Safety |Patient Education | Clinical Judgment
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6. Which legislation authorizes the FDA to determine the safetyof a drug before its marketing?
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a. Federal Food, Drug, and Cosmetic Act (1938)
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b. Durham Humphrey Amendment (1952) n n n

, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
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Edition
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c. Controlled Substances Act (1970) n n n


d. KefauverHarris Drug Amendment (1962) n n n n




ANS: A n


The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
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nsafety of all drugs before marketing. Later amendments and acts helped tighten FDA control
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and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that
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ncannot be used safely without medical supervision and restricts their sale to prescription by
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nalicensed practitioner. The Controlled Substances Act addresses onlycontrolled substances and
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ntheir categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater
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drug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their
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nproducts before marketing them. n n n




DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3
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OBJ: n 5 NAT: NCLEX Client Needs Category: Physiological Integrity n n n n n n


TOP:
n n Nursing Process Step: Assessment n n n


CON: n Safety |Patient Education | Evidence | Health Care Law
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7. Whichclassification does meperidine (Demerol) fall under? n n n n n


a. I
b. II
c. III
d. IV
ANS: B n


Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
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severepsychological and physical dependence. Schedule Idrugs have high potential for abuse
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and no recognized medical use. Schedule III drugs have some potential for abuse. Use may
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lead to low to moderate physical dependence or high psychological dependence. Schedule IV
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drugs have low potential for abuse. Use may lead to limited physical or psychological
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dependence.
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DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2 n n n n n


NAT: NCLEX Client Needs Category: Safe, Effective Care
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nEnvironment
TOP: Nursing Process Step: Assessment CON: Patient Education |Addiction |Pain
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8. Which action would the FDA take to expedite drug development and approval for an outbreakof
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nsmallpox?
a. List smallpox as a health orphan disease.
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b. Omit the preclinical research phase. n n n n


c. Extend the clinical research phase. n n n n


d. Fast track the investigational drug.
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ANS: D n


Once the Investigational New Drug Application has been approved, the drug can receive
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highest priority within the agency, which is called fast tracking. A smallpox outbreak would
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become a priority concern in the world. Orphan diseases are not researched in a priority
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manner. Preclinical research is not omitted. Extending any phase of the research would mean
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a longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical and
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clinical research phase have been completed in a safe manner.
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DIF: Cognitive Level: Knowledge n n REF: p. 7 n OBJ: 5 n