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NR565/ NR 565 AdvancedPharmacologyCareoftheFundamentals
8 8 8 8
Final Exam: Questions and Verified Answers Chamberlai
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1. What8labs8are8used8to8diagnose8Thyroid?:8TSH,8total8T48and8T3,8free8T48and
8 T3
2. Timeframe8for8re-check8of8labs8after8starting8levothyroxine:86-
88wks8after8starting8therapy
3. Signs8and8symptoms8of8hypothyroidism:8Face:8Pale,8puffy,8expressionless8
Skin:8Cold8and8dry
Hair:8Brittle8and8hair8loss
Heart8rate8and8temp8are8lowered
Complaints8by8patient:8lethargy,8fatigue,8intolerance8to8cold8Me
ntation8may8be8impaired
Thyroid8enlargement8if8“'d8levels8of8T38and8T48promoting8excessive8release8of8TSH
4. Treatment8 of8 thyroid8 storm:8High8 dose8 potassium8 iodide8 or8 strong8 iodine8 solu-
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tion8to8suppress8thyroid8hormone8release,8methima
zole8to8suppress8thyroid8hormone8synthesis,
beta8blocker8to8reduce8heart8rate,8sedation8cooling8glucocorticoids8and8IV8fluids
5. Result8of8not8treating8hypothyroidism8during8pregnancy:8permanent8neuro-
8 logical8 defects,8 “'d8 IQ,8 large8 protruding8 tongue,8 potbelly8 dwarfish8 stature,8 impair
ed8 development8 of8 nervous8 system8 bone8 teeth8 and8 muscles.
6. Medication8to8treat8symptoms8of8hyperthyroidism8(notice8this8is8treating8sy
mptoms8and8not8the8hyperthyroidism8itself):8Metoprolol8could8be8used8to8treat8t
achycardia8experienced8with8hyperthyroidism,8but8it8does8not8treat8 hyperthyroidis
m8 itself.
7. Drug/Food/Supplement8interactions8with8levothyroxine8Absorption8RE
-8DUCED8 by::8 Histamine8 28 receptor8 blockers8 (Cimetidine8 [Tagamet])
Proton8pump8inhibitors8(Lansoprazole)8Sucralfat
e8(Carafate)
Cholestyramine8(Questran)8Colestip
ol8(Colestid)
Aluminum8containing8antacids8(maalox,8mylanta)8Ca
lcium8supplements8(tums,8os-cal)
Iron8supple
ments
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Magnesium8 salts8Orlis
tat8(Xenical)
*848hours8between8levothyroxine8and8the8above8meds8is8recommended8and8food8red
uces8absorption8as8well
8. How8to8confirm8a8diagnosis8of8DM8prior8to8beginning8treatment:8Hemoglobin
8 A1C8>86.5%,
Fasting8plasma8glucose8g81268mg/dL,8Random8plasma8glucose8g2008mg/dL8plus8sy
mptoms8of8diabetes,
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