Final Exam: NR565/ NR 565 (Latest
z z z z z
2023/2024 Update) Advanced
z z z z
Pharmacology Exam Review|
z z z
Questions and Verified
z z z
Answers -Chamberlain z
1. A zpatient zhas za zTSH zof z.28, za zfree zT4 zof z3, zand za zfree zT3 zover z650. zWhat
zmedicationzshould zshe zbe zstarted zon?
Answer: zMethimazole, zPTU, zradioactive ziodine. zThese zlabs zindicate
zhyperthyroidism. zTreatment zfor zthyroid zstorm: zK ziodide zor zstrong
ziodinezsolution zto zsuppress zthyroid zrelease. zMethimazole zto
zsuppress zthyroid zsynthesis.
2. When zis zit zappropriate zto zincrease zinsulin zneeds?
Answer: zPregnancy z(after zfirst ztrimester), zstress, zinfection, zweight
zloss,zadolescent zgrowth zspurt. zDECREASE zfor zexercise zand zfirst
ztrimester.
3. What zis zthe zTDD zof za zperson zthat zweighs z70kg?
IF za zperson zis zeating za z50 zcarb zmeal, zhow zmuch zinsulin zwill zbe zneeded zbased zon
zthe zTDDzfrom zthe zabove zquestion?
Answer: z42 zTDD z: z21 zbasal z21 zbolus z(Wt zin zkg zx z0.6; z50%
zlong zactingzand z50% zrapid zacting)
500 zdivided zby z(the zTDD) z42 z= z12. z(carb zto zinsulin zratio)
zthen z(mealzcarbs) z50 zdivided z12= z4.1 zunits zwith zshort zacting
zinsulin
,4. "As zlong zas zthe zshort-acting zinsulin zis zdrawn zup zfirst zI zcan zmix zmy zinsulin
zglargine zwithzit."
Answer: zOf zthe zlong-acting zmedications, zONLY zNPH zthe
zintermediatezduration zis zsuitable zfor zmixing zwith zthe zshort zaction
zinsulins.
5. A zwomen zwho zis ztaking zPioglitazone zstates, z"I'm zglad zthat zthis zmedication
zpromoteszweight zloss."
Answer: zFirst zthis zmedication zpromotes zincrease zin zLDL zlevels,
zwhichzincreases zcardiovascular zrisk. zAlso, zshe's za zfemale zso zspeak
zabout zexercise zand zweight zbearing zexercise zd/t zpossible zincreased
zrisk zfor zfractures.
6. Glucocorticoid zMOA
Answer: zMost zeffective zin zlong-term zcontrol zof zairway zinflammation
7. Cromolyn zMOA
Answer: zUsed zas zprophylaxis zfor zmild zto zmoderate zasthma
8. Monoclonal zAntibodies zMOA
Answer: zUsed zfor zallergy-related zasthma zand zEosinophilic
zasthma. zOmalizumab zfor zallergy zrelated zand zBen zralizumab,
zmepliz, zand zreslizzare zfor zeosinophilic
9. Leukotriene zMOA
, Answer: zSecond-line ztherapy zto zreduce zinflammation
zandzbronchoconstriction
10. B2 zadrenergic zagonists zMOA
Answer: zCan zbe zused zPRN, zfor zEIB, zCOPD zexacerbations,
zandzmaintenance ztherapy
11. methylxanthines zMOA
Answer: zMaintenance ztherapy zfor zchronic zstable zasthma
z(theophylline).
P. z570. zUse zONLY zif zB2 zor zanticholinergics zare znot zappropriate.
12. anticholinergic zMOA
Answer: zApproved zfor zbronchospasm zrelated zto zCOPD
13. •What zare zsome zrisk zfactors zof zfatal zasthma zattacks?
Answer: zUncontrolled, zhospitalized zrecently, ztriggers,
14. •Roflumilast z(select zall zthat
zapply)z1.Reduces zinflammation
2.Not zintended zduring
zpregnancyz3.Approved zfor
zasthma
4. First-line zdrug zfor zCOPD
Answer: zReduces zinflammation, znot zintended zfor zpregnancy,
zapprovedzonly zfor zCOPD, zSecond-line zdrug zfor zCOPD
, Uses zfor zexacerbations zprophylaxis zin zpts zwith zsevere zCOPD
zwith zazprimary zchronic zbronchitis zcomponent.
15. What zpt zeducation zcan zyou zprovide za zpatient zfor zICS zuse?
Answer: zRinse zd/t zoropharyngeal zcandidiasis zand
zdysphoniaz(hoarseness, zdifficulty zspeaking).
16. What zpatient zteaching zcan za zprovider zgive zwhen zprescribing za zPPI?
Answer: zHypomagnesia zsymptoms: zmuscle zcramps, ztremors,
zcramps, zand zpalpitations. zCheck zMg zlevels zperiodically zespecially
zin zthe zelderly.zGet zenough zcalcium zand zVIT zD. zcall zif zhaving
zdiarrhea z(Cdiff)
17. What zpatient zteaching zcan za zprovider zgive zwhen zprescribing zan zH2RA?
Answer: zReport zlethargy, zsolmnolance, zrestlessness, zconfusion zor
zhallucinations. z(CNS zeffects). zTeach zabout zpossible zreduced
zlibido, zimpotence, zgynecomastia, zpneumonia. zP.594 zCimetidine
zinteracts zwithzCYP zsystem zso zcheck zwith zpt zif zthey zare ztaking
zwarfarin, zphenytoin, ztheophylline, zlidocaine.
18. A zpatient zpresents zwith za zcomplaint zof zreflux zand zconstipation. zHe zstates zthat zhe
zdrinkszenough zwater, zand zadmits zhe zhas zgained z30lbs. zHe zalso zstates zthat zhe zhas
zbeen zhaving z"reflux" ztype zsymptoms. zWhat zare zyour znext zsteps zfor zeducation?
Answer: zEducate zthat zweight zgain zcan zpromote zreflux
zsymptoms, zaskzabout zany zotc zuse zsuch zas zantacids zwhich zmay
zcause zconstipation.
19. zollinger-Ellison zsyndrome zis zdue zto za producing ztumor. zTreatment zis zlong-
termztherapy zof zwhat zmedication zclass?
z z z z z
2023/2024 Update) Advanced
z z z z
Pharmacology Exam Review|
z z z
Questions and Verified
z z z
Answers -Chamberlain z
1. A zpatient zhas za zTSH zof z.28, za zfree zT4 zof z3, zand za zfree zT3 zover z650. zWhat
zmedicationzshould zshe zbe zstarted zon?
Answer: zMethimazole, zPTU, zradioactive ziodine. zThese zlabs zindicate
zhyperthyroidism. zTreatment zfor zthyroid zstorm: zK ziodide zor zstrong
ziodinezsolution zto zsuppress zthyroid zrelease. zMethimazole zto
zsuppress zthyroid zsynthesis.
2. When zis zit zappropriate zto zincrease zinsulin zneeds?
Answer: zPregnancy z(after zfirst ztrimester), zstress, zinfection, zweight
zloss,zadolescent zgrowth zspurt. zDECREASE zfor zexercise zand zfirst
ztrimester.
3. What zis zthe zTDD zof za zperson zthat zweighs z70kg?
IF za zperson zis zeating za z50 zcarb zmeal, zhow zmuch zinsulin zwill zbe zneeded zbased zon
zthe zTDDzfrom zthe zabove zquestion?
Answer: z42 zTDD z: z21 zbasal z21 zbolus z(Wt zin zkg zx z0.6; z50%
zlong zactingzand z50% zrapid zacting)
500 zdivided zby z(the zTDD) z42 z= z12. z(carb zto zinsulin zratio)
zthen z(mealzcarbs) z50 zdivided z12= z4.1 zunits zwith zshort zacting
zinsulin
,4. "As zlong zas zthe zshort-acting zinsulin zis zdrawn zup zfirst zI zcan zmix zmy zinsulin
zglargine zwithzit."
Answer: zOf zthe zlong-acting zmedications, zONLY zNPH zthe
zintermediatezduration zis zsuitable zfor zmixing zwith zthe zshort zaction
zinsulins.
5. A zwomen zwho zis ztaking zPioglitazone zstates, z"I'm zglad zthat zthis zmedication
zpromoteszweight zloss."
Answer: zFirst zthis zmedication zpromotes zincrease zin zLDL zlevels,
zwhichzincreases zcardiovascular zrisk. zAlso, zshe's za zfemale zso zspeak
zabout zexercise zand zweight zbearing zexercise zd/t zpossible zincreased
zrisk zfor zfractures.
6. Glucocorticoid zMOA
Answer: zMost zeffective zin zlong-term zcontrol zof zairway zinflammation
7. Cromolyn zMOA
Answer: zUsed zas zprophylaxis zfor zmild zto zmoderate zasthma
8. Monoclonal zAntibodies zMOA
Answer: zUsed zfor zallergy-related zasthma zand zEosinophilic
zasthma. zOmalizumab zfor zallergy zrelated zand zBen zralizumab,
zmepliz, zand zreslizzare zfor zeosinophilic
9. Leukotriene zMOA
, Answer: zSecond-line ztherapy zto zreduce zinflammation
zandzbronchoconstriction
10. B2 zadrenergic zagonists zMOA
Answer: zCan zbe zused zPRN, zfor zEIB, zCOPD zexacerbations,
zandzmaintenance ztherapy
11. methylxanthines zMOA
Answer: zMaintenance ztherapy zfor zchronic zstable zasthma
z(theophylline).
P. z570. zUse zONLY zif zB2 zor zanticholinergics zare znot zappropriate.
12. anticholinergic zMOA
Answer: zApproved zfor zbronchospasm zrelated zto zCOPD
13. •What zare zsome zrisk zfactors zof zfatal zasthma zattacks?
Answer: zUncontrolled, zhospitalized zrecently, ztriggers,
14. •Roflumilast z(select zall zthat
zapply)z1.Reduces zinflammation
2.Not zintended zduring
zpregnancyz3.Approved zfor
zasthma
4. First-line zdrug zfor zCOPD
Answer: zReduces zinflammation, znot zintended zfor zpregnancy,
zapprovedzonly zfor zCOPD, zSecond-line zdrug zfor zCOPD
, Uses zfor zexacerbations zprophylaxis zin zpts zwith zsevere zCOPD
zwith zazprimary zchronic zbronchitis zcomponent.
15. What zpt zeducation zcan zyou zprovide za zpatient zfor zICS zuse?
Answer: zRinse zd/t zoropharyngeal zcandidiasis zand
zdysphoniaz(hoarseness, zdifficulty zspeaking).
16. What zpatient zteaching zcan za zprovider zgive zwhen zprescribing za zPPI?
Answer: zHypomagnesia zsymptoms: zmuscle zcramps, ztremors,
zcramps, zand zpalpitations. zCheck zMg zlevels zperiodically zespecially
zin zthe zelderly.zGet zenough zcalcium zand zVIT zD. zcall zif zhaving
zdiarrhea z(Cdiff)
17. What zpatient zteaching zcan za zprovider zgive zwhen zprescribing zan zH2RA?
Answer: zReport zlethargy, zsolmnolance, zrestlessness, zconfusion zor
zhallucinations. z(CNS zeffects). zTeach zabout zpossible zreduced
zlibido, zimpotence, zgynecomastia, zpneumonia. zP.594 zCimetidine
zinteracts zwithzCYP zsystem zso zcheck zwith zpt zif zthey zare ztaking
zwarfarin, zphenytoin, ztheophylline, zlidocaine.
18. A zpatient zpresents zwith za zcomplaint zof zreflux zand zconstipation. zHe zstates zthat zhe
zdrinkszenough zwater, zand zadmits zhe zhas zgained z30lbs. zHe zalso zstates zthat zhe zhas
zbeen zhaving z"reflux" ztype zsymptoms. zWhat zare zyour znext zsteps zfor zeducation?
Answer: zEducate zthat zweight zgain zcan zpromote zreflux
zsymptoms, zaskzabout zany zotc zuse zsuch zas zantacids zwhich zmay
zcause zconstipation.
19. zollinger-Ellison zsyndrome zis zdue zto za producing ztumor. zTreatment zis zlong-
termztherapy zof zwhat zmedication zclass?
