Anki/Pathoma Questions and Answers
Which form of Crigler-Najjar syndrome is more severe ? Correct Ans-Type I
What are the treatments (2) for Crigler-Najjar syndrome type I ? Correct Ans-
plasmapheresis and phototherapy
Crigler-Najjar syndrome type II is _______ severe and responds to ________which increases
liver enzyme synthesis Correct Ans-less; phenobarbital ,
________ syndrome is due to a deficiency of bilirubin canalicular transport protein Correct
Ans-Dubin-Johnson
Does Dubin-Johnson syndrome result in unconjugated or conjugated hyperbilirubinemia ?
Correct Ans-Conjugated
Dubin-Johnson syndrome presents with a _______, but is otherwise not clinically significant
Correct Ans-grossly black liver
_______ is similar to Dubin-Johnson syndrome , but milder and Correct Ans-Rotor
syndrome; WITHOUT black liver
Does Rotor syndrome result in unconjugated or conjugated hyperbilirubinemia ? Correct
Ans-Conjugated
, Anki/Pathoma Questions and Answers
What type of jaundice is associated with gallstones , parasites , and liver fluke ? Correct
Ans-Obstructive jaundice
What type of jaundice is associated with cholangiocarcinoma and pancreatic carcinoma ?
Correct Ans-Obstructive jaundice
Does biliary tract obstruction (obstructive jaundice) result in unconjugated or conjugated
hyperbilirubinemia ? Correct Ans-Conjugated
Obstructive jaundice is associated with dark urine due to Correct Ans-increased urine
conjugated bilirubin
Obstructive jaundice is associated with_____ urine urobilinogen Correct Ans-decreased
Obstructive jaundice is associated with _____ stools Correct Ans-pale
Obstructive jaundice is associated with increased serum bile acids , which may cause _______
Correct Ans-pruritus
Obstructive jaundice is associated with_______ , which may cause xanthomas skin finding
Correct Ans-hypercholesterolemia
, Anki/Pathoma Questions and Answers
Obstructive jaundice is associated with ______, GI symptom , with malabsorption of fat-
soluble vitamins Correct Ans-steatorrhea
Does viral hepatitis result in unconjugated or conjugated hyperbilirubinemia ? Correct Ans-
Both
Viral hepatitis is associated with _____ urine due to increased urine conjugated bilirubin
Correct Ans-dark
Viral hepatitis is associated with ______ urine urobilinogen Correct Ans-normal or
decreased
In addition to hepatitis virus , viral hepatitis may also be caused by (2 viruses) Correct Ans-
EBV and CMV
Viral hepatitis is characterized by elevated liver enzymes with Correct Ans-ALT AST
Acute hepatitis is associated with inflammation that involves the lobules of the liver and
portal tracts ; characterized by Correct Ans-apoptosis of hepatocytes
Jaundice is a yellow discoloration of the skin and/or sclera Correct Ans-
What is the earliest sign of jaundice? Correct Ans-Scleral icterus
Which form of Crigler-Najjar syndrome is more severe ? Correct Ans-Type I
What are the treatments (2) for Crigler-Najjar syndrome type I ? Correct Ans-
plasmapheresis and phototherapy
Crigler-Najjar syndrome type II is _______ severe and responds to ________which increases
liver enzyme synthesis Correct Ans-less; phenobarbital ,
________ syndrome is due to a deficiency of bilirubin canalicular transport protein Correct
Ans-Dubin-Johnson
Does Dubin-Johnson syndrome result in unconjugated or conjugated hyperbilirubinemia ?
Correct Ans-Conjugated
Dubin-Johnson syndrome presents with a _______, but is otherwise not clinically significant
Correct Ans-grossly black liver
_______ is similar to Dubin-Johnson syndrome , but milder and Correct Ans-Rotor
syndrome; WITHOUT black liver
Does Rotor syndrome result in unconjugated or conjugated hyperbilirubinemia ? Correct
Ans-Conjugated
, Anki/Pathoma Questions and Answers
What type of jaundice is associated with gallstones , parasites , and liver fluke ? Correct
Ans-Obstructive jaundice
What type of jaundice is associated with cholangiocarcinoma and pancreatic carcinoma ?
Correct Ans-Obstructive jaundice
Does biliary tract obstruction (obstructive jaundice) result in unconjugated or conjugated
hyperbilirubinemia ? Correct Ans-Conjugated
Obstructive jaundice is associated with dark urine due to Correct Ans-increased urine
conjugated bilirubin
Obstructive jaundice is associated with_____ urine urobilinogen Correct Ans-decreased
Obstructive jaundice is associated with _____ stools Correct Ans-pale
Obstructive jaundice is associated with increased serum bile acids , which may cause _______
Correct Ans-pruritus
Obstructive jaundice is associated with_______ , which may cause xanthomas skin finding
Correct Ans-hypercholesterolemia
, Anki/Pathoma Questions and Answers
Obstructive jaundice is associated with ______, GI symptom , with malabsorption of fat-
soluble vitamins Correct Ans-steatorrhea
Does viral hepatitis result in unconjugated or conjugated hyperbilirubinemia ? Correct Ans-
Both
Viral hepatitis is associated with _____ urine due to increased urine conjugated bilirubin
Correct Ans-dark
Viral hepatitis is associated with ______ urine urobilinogen Correct Ans-normal or
decreased
In addition to hepatitis virus , viral hepatitis may also be caused by (2 viruses) Correct Ans-
EBV and CMV
Viral hepatitis is characterized by elevated liver enzymes with Correct Ans-ALT AST
Acute hepatitis is associated with inflammation that involves the lobules of the liver and
portal tracts ; characterized by Correct Ans-apoptosis of hepatocytes
Jaundice is a yellow discoloration of the skin and/or sclera Correct Ans-
What is the earliest sign of jaundice? Correct Ans-Scleral icterus
