PC 707 Module 1 Questions And Complete
Answers
What is the route of medication when taken orally? (1) intestinal tract (2) portal vein (3)
liver (4) hepatic artery (5) systemic circulation (6) hepatic vein
Where does absorption primarily take place? GI tract and small intestine
What is the pharmokinetic process of how much drug ends up in the body? Absorption
Because not all of the administered dosage may be dissolved or absorbed or survive liver
passage, only a fraction of an administered dosage makes it to the bloodstream. This is called
_______. Bioavailability
What is the maximum blood level that is achieved following drug administration? Peak
Blood Level
What is the process of moving drugs throughout the body? Distribution
What protein do most drugs bind to? Albumin
, PC 707 Module 1 Questions And Complete
Answers
If a drug is all bound in protein, is it more or less available? Less available
If a patient has more protein binding, do you need to increase or decrease dosing of the drug?
increase
Drugs that are ________ are not able to activate receptors unless they are free Protein
bound
Stopping or starting a drug that binds to plasma protein changes the free drug levels of other
__________. Protein bound drugs
What is a hypothetical value that reflects the volume in which a drug would need to dissolved to
explain the relationship between dosage and blood levels? Volume distribution
What is a drug that binds to a receptor and activates the receptor to produce a biological
response? Agonist
, PC 707 Module 1 Questions And Complete
Answers
What is a drug that binds to a receptor and does not allow a drug to bind thus making the drug
inactive? Antagonist
Where are most drugs excreted? Kidneys
Where do drugs break down in the body? Liver (via enzymatic processes)
What is the process of changing one chemical into another, and the process either creates or uses
energy? metabolism
Metabolism (Review CYP450 metabolism. Understand the difference between inducers and
inhibitors. What happens if two drugs are taken that use the same pathway?) One may
inhibit and one may enhance the system, it will lead to increases or decreases of different drugs
If enzyme prevent CYP450, what will happen to the drug in the body? Increase in
pharamacologic action of drug
Answers
What is the route of medication when taken orally? (1) intestinal tract (2) portal vein (3)
liver (4) hepatic artery (5) systemic circulation (6) hepatic vein
Where does absorption primarily take place? GI tract and small intestine
What is the pharmokinetic process of how much drug ends up in the body? Absorption
Because not all of the administered dosage may be dissolved or absorbed or survive liver
passage, only a fraction of an administered dosage makes it to the bloodstream. This is called
_______. Bioavailability
What is the maximum blood level that is achieved following drug administration? Peak
Blood Level
What is the process of moving drugs throughout the body? Distribution
What protein do most drugs bind to? Albumin
, PC 707 Module 1 Questions And Complete
Answers
If a drug is all bound in protein, is it more or less available? Less available
If a patient has more protein binding, do you need to increase or decrease dosing of the drug?
increase
Drugs that are ________ are not able to activate receptors unless they are free Protein
bound
Stopping or starting a drug that binds to plasma protein changes the free drug levels of other
__________. Protein bound drugs
What is a hypothetical value that reflects the volume in which a drug would need to dissolved to
explain the relationship between dosage and blood levels? Volume distribution
What is a drug that binds to a receptor and activates the receptor to produce a biological
response? Agonist
, PC 707 Module 1 Questions And Complete
Answers
What is a drug that binds to a receptor and does not allow a drug to bind thus making the drug
inactive? Antagonist
Where are most drugs excreted? Kidneys
Where do drugs break down in the body? Liver (via enzymatic processes)
What is the process of changing one chemical into another, and the process either creates or uses
energy? metabolism
Metabolism (Review CYP450 metabolism. Understand the difference between inducers and
inhibitors. What happens if two drugs are taken that use the same pathway?) One may
inhibit and one may enhance the system, it will lead to increases or decreases of different drugs
If enzyme prevent CYP450, what will happen to the drug in the body? Increase in
pharamacologic action of drug
