Final exam BCH 361
The elements that are essential for life, and make up over 90% of cellular dry weight include: - correct
answer ✔✔*CHNOPS*
Carbon
Hydrogen
Nitrogen
Oxygen
Phosphorus
Sulfur
The redox cofactor ubiquinone is necessary for converting energy from electron transport to the form of
chemical bond energy in ATP. In which organelle would you expect to find most ubiquinone? - correct
answer ✔✔Mitochondria
Ribosomes, the protein synthesis complex, are often bound to which organelle? - correct answer
✔✔Rough endoplasmic reticulum
in Eukaryotic cells what organelle possesses a double membrane system? - correct answer
✔✔Mitochondria & Nucleus
Osmosis occurs in order to relieve concentration gradients across membrane. is cells are placed in
HYPOtonic solution they will swell and burst as water rushes in to relieve the gradient. this process is
known as .. - correct answer ✔✔Hemolysis
The property of water that is most responsible for its unique thermal properties and utility as a biological
solvent is: - correct answer ✔✔Hydrogen Bonding
Aspartate and lysine are in the active site of an enzyme. They are both known to participate directly in
catalysis, the pKa's of the residues are found to be 3.2 and 9.6. The optimum pH for the enzyme is 6.4.
, Which forms of these 2 residues will predominate when the enzyme is most active? - correct answer
✔✔Aspartate is deprotonated; Lysine is protonated
When a song acid is added to a buffer system what reaction occurs to neutralize the acid and resist large
changes in pH? - correct answer ✔✔The conjugate base will react with the protons making more of the
weak acid
The conjugate base for HPO4^2- is... - correct answer ✔✔PO4^3-
Calculate the pH of a mixture of 0.30M acetic Acid and 0.10 M sodium acetate . The Ka of acetic acid is
1.73 x10^-5. - correct answer ✔✔4.28
For an endothermic reaction the be spontaneous, what must occur? - correct answer ✔✔The entropy
must increase substantially
the oxidation of glucose molecules to form CO2 and H2O is a __________ process. - correct answer
✔✔Exergonic
Which AA does not exhibit chirality? - correct answer ✔✔Glycine
Interactions in which form alpha-helices and beta-sheets give rise to _____ structure while interactions
between two subunits constitute ______ structure. - correct answer ✔✔secondary
quaternary
An AAA has a allow acidic pI value. What AA is it likely to be? - correct answer ✔✔Aspartic Acid
The R-groups of which AA could participate in the formation of salt bridge electrostatic interaction? -
correct answer ✔✔Lysine & Glutamate
What level of protein structure involves hydrophobic interaction, electrostatic interactions, hydrogen
bonds and covalent bonds between the side chains of AA that are far apart in the AA sequence? - correct
answer ✔✔Tertiary structure
The elements that are essential for life, and make up over 90% of cellular dry weight include: - correct
answer ✔✔*CHNOPS*
Carbon
Hydrogen
Nitrogen
Oxygen
Phosphorus
Sulfur
The redox cofactor ubiquinone is necessary for converting energy from electron transport to the form of
chemical bond energy in ATP. In which organelle would you expect to find most ubiquinone? - correct
answer ✔✔Mitochondria
Ribosomes, the protein synthesis complex, are often bound to which organelle? - correct answer
✔✔Rough endoplasmic reticulum
in Eukaryotic cells what organelle possesses a double membrane system? - correct answer
✔✔Mitochondria & Nucleus
Osmosis occurs in order to relieve concentration gradients across membrane. is cells are placed in
HYPOtonic solution they will swell and burst as water rushes in to relieve the gradient. this process is
known as .. - correct answer ✔✔Hemolysis
The property of water that is most responsible for its unique thermal properties and utility as a biological
solvent is: - correct answer ✔✔Hydrogen Bonding
Aspartate and lysine are in the active site of an enzyme. They are both known to participate directly in
catalysis, the pKa's of the residues are found to be 3.2 and 9.6. The optimum pH for the enzyme is 6.4.
, Which forms of these 2 residues will predominate when the enzyme is most active? - correct answer
✔✔Aspartate is deprotonated; Lysine is protonated
When a song acid is added to a buffer system what reaction occurs to neutralize the acid and resist large
changes in pH? - correct answer ✔✔The conjugate base will react with the protons making more of the
weak acid
The conjugate base for HPO4^2- is... - correct answer ✔✔PO4^3-
Calculate the pH of a mixture of 0.30M acetic Acid and 0.10 M sodium acetate . The Ka of acetic acid is
1.73 x10^-5. - correct answer ✔✔4.28
For an endothermic reaction the be spontaneous, what must occur? - correct answer ✔✔The entropy
must increase substantially
the oxidation of glucose molecules to form CO2 and H2O is a __________ process. - correct answer
✔✔Exergonic
Which AA does not exhibit chirality? - correct answer ✔✔Glycine
Interactions in which form alpha-helices and beta-sheets give rise to _____ structure while interactions
between two subunits constitute ______ structure. - correct answer ✔✔secondary
quaternary
An AAA has a allow acidic pI value. What AA is it likely to be? - correct answer ✔✔Aspartic Acid
The R-groups of which AA could participate in the formation of salt bridge electrostatic interaction? -
correct answer ✔✔Lysine & Glutamate
What level of protein structure involves hydrophobic interaction, electrostatic interactions, hydrogen
bonds and covalent bonds between the side chains of AA that are far apart in the AA sequence? - correct
answer ✔✔Tertiary structure
