NURS 5315 Exam 2: Concept and Clinical
Condition Part II | Questions with Answers
Verified 100% Correct
What are some clinical manifestations of Iron Deficiency Anemia? (10) - ✔✔Spoon shaped
nails
Glossitis (tongue inflammation)
Pale tissues
SOB
Hypoxia
Fatigue
Mouth pain
Angular stomatitis
Dysphasia
Hyposalivation
What causes polycythemia in the newborn? - ✔✔Hypoxic intrauterine environment
stimulates increased erythropoietin production (polycythemia)
Which white blood cell remains elevated during the 1st year of life? (Likely due to risk of
allergy) - ✔✔Eosinophils
Patient with AIDS, Lupus, rheumatoid arthritis, chronic hepatitis, and chronic kidney disease are
most at risk for what type of anemia? - ✔✔Anemia of Chronic Disease (AOCD)
Sickle Cell Anemia can be seen as early as what age? - ✔✔6-12 months
,What type of Hemoglobin is involved in Sickle Cell anemia? - ✔✔Hemoglobin S
What causes an increase in infections when a patient has sickle cell anemia? - ✔✔The sickle
shape of the RBC will causing organ infarction, RBC experience hemolysis in the spleen and
cause functional asplenia causing the patient to be more susceptible to infections
Why would a sickle cell patient have jaundice? - ✔✔Due to their abnormal shape, sickled red
blood cells are more prone to hemolysis, which releases the yellowish-colored bilirubin into the
system. In sickle cell patients, the breakdown of red blood cells occurs faster than the liver can
filter, accumulating excessive bilirubin in the body, which causes jaundice.
ABO or Rh incompatibility cause problems during the mothers first or second pregnancy and
leads to what type of anemia in the fetus? - ✔✔Second pregnancy, Hemolytic Disease of the
Fetus and Newborn (HDFN)
Kernicterus in infants with HDFN is caused by what compound accumulated on the brain? -
✔✔Bilirubin
What causes polycythemia in the newborn? - ✔✔Hypoxic intrauterine environment
stimulates erythropoietin production
Neutrophils count is highest ____ to ____ hours after birth. - ✔✔6-12 hours
At what point is Neutrophil count in newborn the same as adults levels? - ✔✔2 weeks
What are some reasons the elderly are at increased risk for anemia? (5) - ✔✔1. RBCs
replenished at a slower rate
2. Iron binding capacity and intestinal absorption are decreased
3. RBC plasma membrane is more fragile
4. Chronic diseases suppress erythropoiesis
, 5. Lymphocytes function decreases
What is the name of the system of channels that runs from the inner most portion of the
platelet and opens to the outside of the platelet? - ✔✔The Open Canalicular System (OCS)
What is the peripheral zone of the platelet made of? - ✔✔Phospholipids
Aspirin inhibits the action of ____ in the Arachidonic Pathway by blocking COX1? -
✔✔Thromboxane A2 (TXA2)
What is the role of thromboxane A2? - ✔✔TXA2 binds to the thromboxane receptor and is
responsible for binding platelets together
What the mechanism of Aspirin? - ✔✔Aspirin inhibits the formation of TXA2 by blocking the
COX1 pathway of the arachidonic pathway
Fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombosespondin all bind to
which receptor to cause platelet aggregation? - ✔✔GPIIb/IIIa receptor 2b 3a
Which two receptors are receptors for collagen? - ✔✔GP Ia/IIa and GP VI GP(1a, 2a, 6)
GP Ib/IX/V is membrane receptor for? - ✔✔Von Wilebrand Factor (vWF)
In the the secretion stage of Primary Hemostasis ADP does what? - ✔✔ADP is secreted by
platelets, they enhance adhesion and recruit additional platelets
AD - think Adhesion P - think Platelets
Condition Part II | Questions with Answers
Verified 100% Correct
What are some clinical manifestations of Iron Deficiency Anemia? (10) - ✔✔Spoon shaped
nails
Glossitis (tongue inflammation)
Pale tissues
SOB
Hypoxia
Fatigue
Mouth pain
Angular stomatitis
Dysphasia
Hyposalivation
What causes polycythemia in the newborn? - ✔✔Hypoxic intrauterine environment
stimulates increased erythropoietin production (polycythemia)
Which white blood cell remains elevated during the 1st year of life? (Likely due to risk of
allergy) - ✔✔Eosinophils
Patient with AIDS, Lupus, rheumatoid arthritis, chronic hepatitis, and chronic kidney disease are
most at risk for what type of anemia? - ✔✔Anemia of Chronic Disease (AOCD)
Sickle Cell Anemia can be seen as early as what age? - ✔✔6-12 months
,What type of Hemoglobin is involved in Sickle Cell anemia? - ✔✔Hemoglobin S
What causes an increase in infections when a patient has sickle cell anemia? - ✔✔The sickle
shape of the RBC will causing organ infarction, RBC experience hemolysis in the spleen and
cause functional asplenia causing the patient to be more susceptible to infections
Why would a sickle cell patient have jaundice? - ✔✔Due to their abnormal shape, sickled red
blood cells are more prone to hemolysis, which releases the yellowish-colored bilirubin into the
system. In sickle cell patients, the breakdown of red blood cells occurs faster than the liver can
filter, accumulating excessive bilirubin in the body, which causes jaundice.
ABO or Rh incompatibility cause problems during the mothers first or second pregnancy and
leads to what type of anemia in the fetus? - ✔✔Second pregnancy, Hemolytic Disease of the
Fetus and Newborn (HDFN)
Kernicterus in infants with HDFN is caused by what compound accumulated on the brain? -
✔✔Bilirubin
What causes polycythemia in the newborn? - ✔✔Hypoxic intrauterine environment
stimulates erythropoietin production
Neutrophils count is highest ____ to ____ hours after birth. - ✔✔6-12 hours
At what point is Neutrophil count in newborn the same as adults levels? - ✔✔2 weeks
What are some reasons the elderly are at increased risk for anemia? (5) - ✔✔1. RBCs
replenished at a slower rate
2. Iron binding capacity and intestinal absorption are decreased
3. RBC plasma membrane is more fragile
4. Chronic diseases suppress erythropoiesis
, 5. Lymphocytes function decreases
What is the name of the system of channels that runs from the inner most portion of the
platelet and opens to the outside of the platelet? - ✔✔The Open Canalicular System (OCS)
What is the peripheral zone of the platelet made of? - ✔✔Phospholipids
Aspirin inhibits the action of ____ in the Arachidonic Pathway by blocking COX1? -
✔✔Thromboxane A2 (TXA2)
What is the role of thromboxane A2? - ✔✔TXA2 binds to the thromboxane receptor and is
responsible for binding platelets together
What the mechanism of Aspirin? - ✔✔Aspirin inhibits the formation of TXA2 by blocking the
COX1 pathway of the arachidonic pathway
Fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombosespondin all bind to
which receptor to cause platelet aggregation? - ✔✔GPIIb/IIIa receptor 2b 3a
Which two receptors are receptors for collagen? - ✔✔GP Ia/IIa and GP VI GP(1a, 2a, 6)
GP Ib/IX/V is membrane receptor for? - ✔✔Von Wilebrand Factor (vWF)
In the the secretion stage of Primary Hemostasis ADP does what? - ✔✔ADP is secreted by
platelets, they enhance adhesion and recruit additional platelets
AD - think Adhesion P - think Platelets
