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Blood banking - Minor blood groups Review Questions with complete Solutions Graded A+

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Blood banking - Minor blood groups Review Questions with complete Solutions Graded A+ 010 - Answers ISBT number of Diego blood system Dia antigen - Answers Antigen which acts as a useful tool in anthropologic studies of Mongolian ancestry Anion exchange molecule (AE-1) - Answers Dia and Dib antigens are located where? Hereditary spherocytosis, congenital acanthocytosis, Southeast Asian ovalocytosis - Answers Defects of AE-1 and shows weak expression of Diego antigen Dia+ - Answers Diego antigen which is prevalent in American Indians, Japanese, and Chinese Dib+ - Answers Diego antigen which is prevalent in Whites 011 - Answers ISBT number of Cartwright blood group system Yta - Answers High-incidence Cartwright antigen which is present in 99.8% of the general population Ytb - Answers Low-incidence Cartwright antigen which is present in 8% of the general population Erythrocyte acetylcholinesterase - Answers Where are Cartwright antigens found on? Yes, significant (reactive in IAT) - Answers Are Cartwright antibodies clinically significant? 012 - Answers ISBT number of Xg blood group system Xga - Answers Only antigen identified with no antithetical partner Short arm of X chromosome - Answers Genes that code for Xg allele is located on? CD99 molecule - Answers Xg antigen is carried by a protein with cell adhesion properties that has been demonstrated to have homology with? Xga - Answers Approximately 89% of the female population expresses this antigen while only 66% of the male population expresses it 013 - Answers ISBT number of the Scianna blood group system Sc2 - Answers The prevalence of this Scianna antigen in Northern Europeans is 1% but is higher in the Mennonite population. Anti-Sc3 - Answers What is the clinically significant antibody in the Scianna blood group system? Sc-1,-2,-3 - Answers This rare null phenotype has been observed in the Marshall Islands and New Guinea 014 - Answers ISBT number of the Dombrock blood group system Mono-ADP-Ribosyltransferase 4 - Answers Where are Dombrock antigens carried on? Yes, caused moderate transfusion reactions - Answers Are Dombrock antibodies clinically significant? 015 - Answers ISBT number of Colton blood group system Aquaporin 1 (AQP1), Channel-forming integral protein (CHIP) - Answers Where are Colton antigens carried on? Anti-Coa and anti-Cob - Answers Colton antibodies which are IgG and cause acute to delayed transfusion reactions Anti-CO3 - Answers Colton antibody which is IgG and associated with severe HDFN 016 - Answers ISBT number of Landsteiner-Wiener blood group system Intracellular adhesion molecule 4 (ICAM4) - Answers Where are LW antigens carried on? LW(a-b-) - Answers LW has a phenotypic relationship with the D antigen; Rhnull RBCs type as ______ Rhnull - Answers Anti-LW differs from anti-D because it agglutinates Rh(+) and Rh(-) except ______ DTT treated - Answers Anti-LW differs from anti-D because it does not react with _____ RBCs 017 - Answers ISBT number of Chido-Rodgers blood system C4A, C4B - Answers Rodgers and Chido antigens are respectively found on the C4D fragments of the ____ and ____ glycoproteins of the C4 complement component Anti-Ch/Rg - Answers These antibodies were formerly grouped as HTLA and usually stimulated in multi-transfused individuals lacking one or more of the corresponding antigens 020 - Answers ISBT number of the Gerbich blood system Gerbich phenotype (Ge:-2,-3,4) - Answers What phenotype of the Gerbich system is common in Papua New Guineans, Europeans, Africans, Native Americans, Japanese, and Polynesians? Yus phenotype (Ge:-2,3,4) - Answers What phenotype of the Gerbich system is common in Mexicans and Israelis? Leach phenotype (Ge:-2,-3,-4) - Answers What phenotype of the Gerbich system is common in Gerbich null within Papua New Guinea Elliptocytosis - Answers What type of poikilocytosis is found in Gerbich null phenotype? Glycophorins C and/or D - Answers Where are GE antigens expressed on? 021 - Answers ISBT number of the Cromer blood group system? Decay accelerating factor (DAF) or CD55 - Answers Where are Cromer antigens located on? Black individuals - Answers CROM antibodies are rarely observed, with the majority of examples presenting in? 022 - Answers ISBT number of the Knops blood group system Complement receptor one (CR1) - Answers Where are Knops antigens found on? 023 - Answers ISBT number of the Indian blood group system (Hemapoietic isoform of) CD44 marker - Answers Where are Indian blood group antigens found on? Inb antigen - Answers What antigen of the Indian blood system are found in 96% of Indians and Whites? Ina antigen - Answers What antigen of the Indian blood system are found in 4% of Indians, 11% Iranians, and 12% Arabs? 024 - Answers ISBT number of the OK blood group system CD147 - Answers Where are OK antigens found on? 025 - Answers ISBT number of the Raph blood group system MER2 - Answers What is the only antigen of the Raph blood system? CD151 (a tetraspanin) - Answers Where is the Raph antigen found on? 026 - Answers ISBT number of the John Milton Hagen blood group system CD108 - Answers Where is the JMH protein found on? 029 - Answers ISBT number of the Gill blood group system Aquaporin 3 - Answers Where is the GIL antigen found on? 030 - Answers ISBT number of the Rh-associated glycoprotein blood system Duclos, OIa - Answers The two antigens of the RHAG system are RHAG1 or _____ and RHAG2 or _____; the former was previously in the high-prevalence series while the latter was in the low-prevalence series

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Blood banking - Minor blood groups Review Questions with complete Solutions Graded A+

010 - Answers ISBT number of Diego blood system

Dia antigen - Answers Antigen which acts as a useful tool in anthropologic studies of Mongolian ancestry

Anion exchange molecule (AE-1) - Answers Dia and Dib antigens are located where?

Hereditary spherocytosis, congenital acanthocytosis, Southeast Asian ovalocytosis - Answers Defects of
AE-1 and shows weak expression of Diego antigen

Dia+ - Answers Diego antigen which is prevalent in American Indians, Japanese, and Chinese

Dib+ - Answers Diego antigen which is prevalent in Whites

011 - Answers ISBT number of Cartwright blood group system

Yta - Answers High-incidence Cartwright antigen which is present in 99.8% of the general population

Ytb - Answers Low-incidence Cartwright antigen which is present in 8% of the general population

Erythrocyte acetylcholinesterase - Answers Where are Cartwright antigens found on?

Yes, significant (reactive in IAT) - Answers Are Cartwright antibodies clinically significant?

012 - Answers ISBT number of Xg blood group system

Xga - Answers Only antigen identified with no antithetical partner

Short arm of X chromosome - Answers Genes that code for Xg allele is located on?

CD99 molecule - Answers Xg antigen is carried by a protein with cell adhesion properties that has been
demonstrated to have homology with?

Xga - Answers Approximately 89% of the female population expresses this antigen while only 66% of the
male population expresses it

013 - Answers ISBT number of the Scianna blood group system

Sc2 - Answers The prevalence of this Scianna antigen in Northern Europeans is 1% but is higher in the
Mennonite population.

Anti-Sc3 - Answers What is the clinically significant antibody in the Scianna blood group system?

Sc-1,-2,-3 - Answers This rare null phenotype has been observed in the Marshall Islands and New Guinea

014 - Answers ISBT number of the Dombrock blood group system

Mono-ADP-Ribosyltransferase 4 - Answers Where are Dombrock antigens carried on?

, Yes, caused moderate transfusion reactions - Answers Are Dombrock antibodies clinically significant?

015 - Answers ISBT number of Colton blood group system

Aquaporin 1 (AQP1), Channel-forming integral protein (CHIP) - Answers Where are Colton antigens
carried on?

Anti-Coa and anti-Cob - Answers Colton antibodies which are IgG and cause acute to delayed transfusion
reactions

Anti-CO3 - Answers Colton antibody which is IgG and associated with severe HDFN

016 - Answers ISBT number of Landsteiner-Wiener blood group system

Intracellular adhesion molecule 4 (ICAM4) - Answers Where are LW antigens carried on?

LW(a-b-) - Answers LW has a phenotypic relationship with the D antigen; Rhnull RBCs type as ______

Rhnull - Answers Anti-LW differs from anti-D because it agglutinates Rh(+) and Rh(-) except ______

DTT treated - Answers Anti-LW differs from anti-D because it does not react with _____ RBCs

017 - Answers ISBT number of Chido-Rodgers blood system

C4A, C4B - Answers Rodgers and Chido antigens are respectively found on the C4D fragments of the
____ and ____ glycoproteins of the C4 complement component

Anti-Ch/Rg - Answers These antibodies were formerly grouped as HTLA and usually stimulated in multi-
transfused individuals lacking one or more of the corresponding antigens

020 - Answers ISBT number of the Gerbich blood system

Gerbich phenotype (Ge:-2,-3,4) - Answers What phenotype of the Gerbich system is common in Papua
New Guineans, Europeans, Africans, Native Americans, Japanese, and Polynesians?

Yus phenotype (Ge:-2,3,4) - Answers What phenotype of the Gerbich system is common in Mexicans and
Israelis?

Leach phenotype (Ge:-2,-3,-4) - Answers What phenotype of the Gerbich system is common in Gerbich
null within Papua New Guinea

Elliptocytosis - Answers What type of poikilocytosis is found in Gerbich null phenotype?

Glycophorins C and/or D - Answers Where are GE antigens expressed on?

021 - Answers ISBT number of the Cromer blood group system?

Decay accelerating factor (DAF) or CD55 - Answers Where are Cromer antigens located on?

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