NURS-6501N
Advanced
Pathophysiology
David Mungai [Date] [Course title]
,Midterm Exam - NURS-6501N Advanced Pathophysiology
Question 17
1 pts
Which of the following statements best describes the Glagov phenomenon in the context of
atherosclerotic disease?
O Vessel wall diameter increases indefinitely with plaque growth to cause stenosis of the
vessel
Vessel wall remodeling occurs in response to early plaque accumulation without causing
significant luminal stenosis
Plaque calcification stabilizes the vessel wall, preventing lumen obstruction despite
increasing plaque size
Blood flow is enhanced in response to plaque deposition as a result of angiogenesis
around the obstructed vessel
Correct Answer: Vessel wall remodeling occurs in response to early plaque accumulation
without causing significant luminal stenosis.
Question 18
1 pts
Which endocrine disorder is associated with decreased bone resorption and consequent
thickening of the bone (osteosclerosis)?
Diabetes mellitus
Hypoparathyroidism
Cushing Syndrome
Hyperthyroidism
Correct Answer: Hypoparathyroidism
Question 19
1 pts
A middle-aged construction worker has spent the last 25 years using a jackhammer to cut up
sidewalks but has consistently refused to wear protective equipment. He now presents with
,worsening shortness of breath, and a chest X-ray reveals diffuse fibrosis in his lung tissue. What
type of lung disease would be anticipated by pulmonary function testing (PFT) in this case?
Obstructive lung disease
Restrictive lung disease
Asthma-like lung disease
No lung disease would be detectable by PFT.
Correct Answer: Restrictive lung disease
Question 20
1 pts
A patient is admitted to the hospital with severe sepsis secondary to bacterial pneumonia. Which
of the following types of cell death is most likely to be associated with this patient’s condition?
Necrosis
Apoptosis
Pyroptosis
Autophagy
Correct Answer: Necrosis
Question 21
1 pts
A ventricular septal defect, with blood flow from the left ventricle to the right ventricle, is an
example of which type of cardiac pathology?
Shunted flow
Regurgitant flow
Flow obstruction
Pump failure
Correct Answer: Shunted flow
Question 22
, 1 pts
A patient with diverticulosis presents with brisk, bright red bleeding per rectum. The patient
denies any abdominal pain. Which term accurately describes this presentation, and where is the
most likely source of the bleeding?
Melena; lower gastrointestinal tract
Melena; upper gastrointestinal tract
Hematochezia; lower gastrointestinal tract
Hematochezia; upper gastrointestinal tract
Correct Answer: Hematochezia; lower gastrointestinal tract
Question 23
1 pts
A patient presents with left lower quadrant abdominal pain, fever, vomiting, and leukocytosis.
These clinical features are most indicative of which condition?
Diverticulitis
Acute cholecystitis
Diverticulosis
Appendicitis
Correct Answer: Diverticulitis
Question 24
1 pts
Autophagy serves a variety of cellular functions but is NOT responsible for which of the
following?
Normal cell turnover
Protein synthesis
Normal cell metabolism
Tissue atrophy
Correct Answer: Protein synthesis