Clinical Immunology and Serology Exam 1 Questions And Correct Answers Verified 100%.

(antigen elimination) First phase following injection - correct answers particulate antigens are removed in about 10-20 minutes through phagocytosis in the monocytic phagocyte system (MΦs in the lungs, liver and spleen). 90% are removed from the circulation on the first passage. Soluble antigens are removed slower because aggregation (through existing antibody) and pinocytosis are slower. (antigen elimination) second phase following injection - correct answers degradation and removal of antigen by enzymatic hydrolysis and intracellular digestion (4-7 days) (antigen elimination) third phase following injection - correct answers immune elimination through newly formed antibody (from clonal expansion) enhances phagocytosis and digestion 2 other cell types which develop from the myeloid progenitor cells are: - correct answers a. Platelets which are involved in blood clotting and inflammation b. Mast cells which are structurally and functionally similar to basophils A T lymphocyte with an antigen receptor which allows it to - correct answers recognize and react to the measles virus would not recognize or respond to the smallpox virus Active immunization - correct answers injection of an infectious agent (dead or alive) or toxoid to confer immunity and result in a secondary response upon re-exposure AgAb binding assays (primary tests)- - correct answers nanogram (10-9) and picogram (10-12) agar gel diffusion - correct answers the precipitin reaction takes place in agar gel or other semisolid media thru which soluble molecules can diffuse. The location and density of the precipitin band is determined by the concentration and rate of diffusion of the molecules (Ag and Ab) agglutination definition - correct answers Ag and Ab reactions involve particulate Ag and the end result is the formation of aggregates (detected by direct observation)