MCB Exam 2 rats UPDATED Actual
Questions and CORRECT Answers
Extensive digestion of chromatin with micrococcal nuclease was found to yield particles
called nucleosome core particles that appear as beads when viewed by electron microscopy.
Which of the following is not found in the nucleosome core particle?
a. Two molecules of H2A protein
b. Two molecules of H3 protein
c. Two molecules of H4 protein
d. One molecule of H1 protein - CORRECT ANSWER- ✔✔d. One molecule of H1 protein
The transfer of information from parent to progeny that is not based on DNA sequences is
known as
a. epigenetic inheritance.
b. non-Mendelian genetics.
c. sex-linked inheritance.
d. Mendelian genetics. - CORRECT ANSWER- ✔✔a. epigenetic inheritance.
In the chromatin around centromeres, nucleosomes are present that have a unique structure in
which the core protein _______ is replaced by _______, and this variant of the nucleosome is
required for protein assembly at the kinetochore.
a. histone H3; CENP-A
,b. histone H3; histone H5
c. histone H1; CENP-A
d. histone H1; histone H5 - CORRECT ANSWER- ✔✔a. histone H3; CENP-A
During metaphase in actively dividing cells, DNA is in
a. heterochromatin.
b. nucleoli.
c. chromosomes.
d. euchromatin. - CORRECT ANSWER- ✔✔c. chromosomes.
A centromere is a
a. region of euchromatin devoid of histones.
b. sequence at the end of chromatids.
c. region where proteins bind to form kinetochores.
d. specific, repeated DNA sequence. - CORRECT ANSWER- ✔✔c. region where proteins
bind to form kinetochores.
Heterochromatin gets its name from the fact that it contains a mixture of active and inactive
genes.
True or False - CORRECT ANSWER- ✔✔False
,The function of telomeres is to
a. condense the chromosomes in preparation for mitosis.
b. ensure chromosome replication and maintenance.
c. hold the sister chromatids together and bind the spindle during mitosis.
d. provide a binding site for DNA polymerase to initiate replication. - CORRECT ANSWER-
✔✔b. ensure chromosome replication and maintenance.
Interaction between the finger-like projections of histones with DNA is based on a charge
attraction
True or False - CORRECT ANSWER- ✔✔True
The extended length of all the DNA in one human cell is about two
a. millimeters.
b. centimeters.
c. meters.
d. kilometers. - CORRECT ANSWER- ✔✔c. meters.
Heterochromatin consists of
a. DNA associated with nucleosomes.
, b. 10-nm chromatin fibers.
c. decondensed, transcriptionally active chromatin.
d. highly condensed, transcriptionally inactive chromatin. - CORRECT ANSWER- ✔✔d.
highly condensed, transcriptionally inactive chromatin.
During mitosis, highly condensed chromosomes consist of two sister chromatids joined at the
a. centrosome.
b. centromere.
c. kinetochore.
d. spindle fiber - CORRECT ANSWER- ✔✔b. centromere
Euchromatin consists of
a. decondensed, transcriptionally active chromatin.
b. 100-nm chromatin fibers.
c. DNA associated with nucleosomes.
d. highly condensed, transcriptionally inactive chromatin. - CORRECT ANSWER- ✔✔a.
decondensed, transcriptionally active chromatin.
The DNA of eukaryotic cells is wrapped around histones to form structures called
a. nucleoli.
Questions and CORRECT Answers
Extensive digestion of chromatin with micrococcal nuclease was found to yield particles
called nucleosome core particles that appear as beads when viewed by electron microscopy.
Which of the following is not found in the nucleosome core particle?
a. Two molecules of H2A protein
b. Two molecules of H3 protein
c. Two molecules of H4 protein
d. One molecule of H1 protein - CORRECT ANSWER- ✔✔d. One molecule of H1 protein
The transfer of information from parent to progeny that is not based on DNA sequences is
known as
a. epigenetic inheritance.
b. non-Mendelian genetics.
c. sex-linked inheritance.
d. Mendelian genetics. - CORRECT ANSWER- ✔✔a. epigenetic inheritance.
In the chromatin around centromeres, nucleosomes are present that have a unique structure in
which the core protein _______ is replaced by _______, and this variant of the nucleosome is
required for protein assembly at the kinetochore.
a. histone H3; CENP-A
,b. histone H3; histone H5
c. histone H1; CENP-A
d. histone H1; histone H5 - CORRECT ANSWER- ✔✔a. histone H3; CENP-A
During metaphase in actively dividing cells, DNA is in
a. heterochromatin.
b. nucleoli.
c. chromosomes.
d. euchromatin. - CORRECT ANSWER- ✔✔c. chromosomes.
A centromere is a
a. region of euchromatin devoid of histones.
b. sequence at the end of chromatids.
c. region where proteins bind to form kinetochores.
d. specific, repeated DNA sequence. - CORRECT ANSWER- ✔✔c. region where proteins
bind to form kinetochores.
Heterochromatin gets its name from the fact that it contains a mixture of active and inactive
genes.
True or False - CORRECT ANSWER- ✔✔False
,The function of telomeres is to
a. condense the chromosomes in preparation for mitosis.
b. ensure chromosome replication and maintenance.
c. hold the sister chromatids together and bind the spindle during mitosis.
d. provide a binding site for DNA polymerase to initiate replication. - CORRECT ANSWER-
✔✔b. ensure chromosome replication and maintenance.
Interaction between the finger-like projections of histones with DNA is based on a charge
attraction
True or False - CORRECT ANSWER- ✔✔True
The extended length of all the DNA in one human cell is about two
a. millimeters.
b. centimeters.
c. meters.
d. kilometers. - CORRECT ANSWER- ✔✔c. meters.
Heterochromatin consists of
a. DNA associated with nucleosomes.
, b. 10-nm chromatin fibers.
c. decondensed, transcriptionally active chromatin.
d. highly condensed, transcriptionally inactive chromatin. - CORRECT ANSWER- ✔✔d.
highly condensed, transcriptionally inactive chromatin.
During mitosis, highly condensed chromosomes consist of two sister chromatids joined at the
a. centrosome.
b. centromere.
c. kinetochore.
d. spindle fiber - CORRECT ANSWER- ✔✔b. centromere
Euchromatin consists of
a. decondensed, transcriptionally active chromatin.
b. 100-nm chromatin fibers.
c. DNA associated with nucleosomes.
d. highly condensed, transcriptionally inactive chromatin. - CORRECT ANSWER- ✔✔a.
decondensed, transcriptionally active chromatin.
The DNA of eukaryotic cells is wrapped around histones to form structures called
a. nucleoli.
