NURS 504 ADVANCED Pharmacology 505 Quiz Questions Answers
Advanced Pharmacology I (NURS 504)
1. What is the maximum daily dose of acetaminophen for a patient with a healthy liver and
minimal alcohol consumption?
Answer: The limit is 4g/day, but it decreases to 3g/day in cases of liver issues or heavy alcohol
use.
2. Why is sublingual medication beneficial?
Answer: It provides rapid absorption and avoids liver metabolism.
3. A patient has experienced three gout attacks in the past year. What type of medication would a
prescriber recommend to reduce flare-ups?
Answer: Urate-lowering medication.
4. Rifampin, a non-specific P450 inducer, has what effect?
Answer: It can shorten the time a patient can remain on the medication by inducing faster
metabolism, potentially requiring higher doses.
5. How do genetic variations influence drug metabolism?
Answer: Genetic differences can affect absorption, drug uptake, and breakdown, leading to
variations in receptor responses.
6. What can happen to drugs metabolized by the liver?
Answer: The metabolites can be stronger, weaker, or excreted unchanged.
7. A patient with frequent gout attacks is prescribed allopurinol and colchicine. What should the
provider inform the patient regarding the regimen?
Answer: Colchicine will be discontinued after six months.
8. Which of the following drugs does NOT have an anti-inflammatory effect?
Answer: Acetaminophen.
9. How do bisphosphonates help in treating osteoporosis?
Answer: Bisphosphonates prevent bone loss by inhibiting the activity of osteoclasts, which are
responsible for breaking down bone. They also lower serum calcium levels while still allowing
normal bone formation and mineralization.
10. What is the role of calcium supplements for patients on bisphosphonates?
Answer: Calcium supplements help maintain bone health, as bisphosphonates slow down bone
resorption and inhibit osteoclast activity.
11. What happens to drugs that undergo a significant first-pass effect?
Answer: They are metabolized too quickly before reaching systemic circulation and may require
a different route of administration.
Advanced Pharmacology I (NURS 504)
1. What is the maximum daily dose of acetaminophen for a patient with a healthy liver and
minimal alcohol consumption?
Answer: The limit is 4g/day, but it decreases to 3g/day in cases of liver issues or heavy alcohol
use.
2. Why is sublingual medication beneficial?
Answer: It provides rapid absorption and avoids liver metabolism.
3. A patient has experienced three gout attacks in the past year. What type of medication would a
prescriber recommend to reduce flare-ups?
Answer: Urate-lowering medication.
4. Rifampin, a non-specific P450 inducer, has what effect?
Answer: It can shorten the time a patient can remain on the medication by inducing faster
metabolism, potentially requiring higher doses.
5. How do genetic variations influence drug metabolism?
Answer: Genetic differences can affect absorption, drug uptake, and breakdown, leading to
variations in receptor responses.
6. What can happen to drugs metabolized by the liver?
Answer: The metabolites can be stronger, weaker, or excreted unchanged.
7. A patient with frequent gout attacks is prescribed allopurinol and colchicine. What should the
provider inform the patient regarding the regimen?
Answer: Colchicine will be discontinued after six months.
8. Which of the following drugs does NOT have an anti-inflammatory effect?
Answer: Acetaminophen.
9. How do bisphosphonates help in treating osteoporosis?
Answer: Bisphosphonates prevent bone loss by inhibiting the activity of osteoclasts, which are
responsible for breaking down bone. They also lower serum calcium levels while still allowing
normal bone formation and mineralization.
10. What is the role of calcium supplements for patients on bisphosphonates?
Answer: Calcium supplements help maintain bone health, as bisphosphonates slow down bone
resorption and inhibit osteoclast activity.
11. What happens to drugs that undergo a significant first-pass effect?
Answer: They are metabolized too quickly before reaching systemic circulation and may require
a different route of administration.
