1|Page
NURS617 EXAM 2 ACTUAL COMPLETE 160 QUESTIONS
AND CORRECT DETAILED ANSWERS (VERIFIED
ANSWERS) |ALREADY GRADED A+||BRAND NEW
VERSION!! COMBINED VERSION PART 1-7
Disadvantages of the Proton-Pump Inhibitors✔✔ ANSWER✔✔- Only
recommended for a maximum of 8-12 weeks because of the marked
suppressive effect they have on gastric acid secretion.
- Alters the absorption of other orally administered drugs; causes
pharmacokinetic drug-drug interactions with them.
- May cause abdominal pain, constipation
- Commonly causes dizziness, headache, diarrhea
- Inhibits dietary protein digestion; [Note: Acid plays a vital role in the
initial digestion of dietary protein.]
- Possibly causes an overgrowth of gastric bacteria and yeast (candida)
because of the loss of the normally inhibitory effects of HCl acid on
gastric bacterial growth.
Advantages of Sucralfate in the Treatment of Acid-Related Disorders✔✔
ANSWER✔✔No absorption; minimizes systemic adverse effects
- No real contraindications
- Can be used therapeutically and "prophylactically"; as a prophylactic
drug,
,2|Page
___ will not prevent ulceration but will be present as soon as an ulcer
begins to form and prevent it from worsening.
Disadvantages of Sucralfate in the Treatment of Acid-Related
Disorders✔✔ ANSWER✔✔Binds to and prevents the absorption of
some other orally administered drugs; capable of causing an inhibitory
pharmacokinetic drug-drug interaction
- Can be inhibited by other acid-suppressing drugs; ___requires acid to
activate, and must be given at least 1 hour before (preferably two hrs.)
the administration of antacids.
- May cause constipation; this is an aluminum-induced effect and is also
caused by the binding by ___ of bile salts. [Note: Those bile salts which
escape reabsorption by the enterohepatic circuit will stimulate
peristalsis in the colon when they come in contact with the colonic
mucosa.]
- Requires precaution in patients with renal insufficiency; excessive
dosing may cause hyperaluminemia. Aluminum can only be excreted by
renal mechanisms, which requires good kidney function.
Advantages of Misoprostol in the Treatment of Acid-Related
Disorders✔✔ ANSWER✔✔Has dual mechanisms of action; production
of gastric mucus and slight suppression of gastric acid.
- Most advantageous as a blocker of the harmful effects of aspirin and
other NSAIDs on the gastric mucosa.
- Available in a combination product with an NSAID drug [diclofenac +
___ (Arthrotec)]; this simplifies drug administration for those patients
who desire to take one tablet instead of two.
,3|Page
Disadvantages of Misoprostol in the Treatment of Acid-Related
Disorders✔✔ ANSWER✔✔Requires precaution in patients with renal
insufficiency
- Contraindicated in pregnancy; it is a potent stimulant of uterine
contraction and can precipitate premature labor. It can be used as an
abortifacient drug in the first trimester.
___ is commonly used in obstetrics as a labor inducer at delivery time.
This use does not fall into the Pregnancy Category because it is
administered at an appropriate time to cause uterine contractions
deliberately.]
- Limitation of use in childbearing-aged females. Pregnancy tests are
required in this group
- Not effective as monotherapy for acid-related diseases; only used to
offset the harmful effects of the NSAIDs on the gastric mucosa.
- May cause diarrhea and abdominal pain.
- Available orally (tablets, capsules, suspension) and IV
-The least sedating drug to treat seizures of any type.✔✔
ANSWER✔✔Advantages of Phenytoin (Dilantin) in tx of epilepsy
- May cause various CNS adverse reactions
- Can produce a rash; the drug should be discontinued, and if the rash is
severe,___ is contraindicated after that.
, 4|Page
- Long-term therapy can produce cosmetic problems; acne, hirsutism,
coarsening of facial features, gingival hyperplasia
- Can produce lymphadenopathy; Can cause hyperglycemia
- Teratogenic in pregnancy (Pregnancy category D)
- Narrow therapeutic window
- Many drug interactions
-Baseline CBC, urinalysis, and liver function tests should be completed
before beginning therapy.✔✔ ANSWER✔✔Disadvantages of Phenytoin
(Dilantin) in tx of epilepsy
- Useful in pain management of trigeminal neuralgia
- Does not produce sedation in normal dosages
- May also be used in the treatment of bipolar disorder✔✔
ANSWER✔✔Advantages of Carbamazepine (Tegretol) in tx of epilepsy
Commonly causes dizziness, diplopia, and ataxia; usually upon initiation
of therapy
- Rare but severe cases of aplastic anemia and agranulocytosis;
- Can provoke N/V early in therapy
- May cause an erythematous skin rash
- May decrease the serum levels of other anticonvulsants since it is a P-
450 enzyme inducer.
- Cannot be abruptly discontinued;
NURS617 EXAM 2 ACTUAL COMPLETE 160 QUESTIONS
AND CORRECT DETAILED ANSWERS (VERIFIED
ANSWERS) |ALREADY GRADED A+||BRAND NEW
VERSION!! COMBINED VERSION PART 1-7
Disadvantages of the Proton-Pump Inhibitors✔✔ ANSWER✔✔- Only
recommended for a maximum of 8-12 weeks because of the marked
suppressive effect they have on gastric acid secretion.
- Alters the absorption of other orally administered drugs; causes
pharmacokinetic drug-drug interactions with them.
- May cause abdominal pain, constipation
- Commonly causes dizziness, headache, diarrhea
- Inhibits dietary protein digestion; [Note: Acid plays a vital role in the
initial digestion of dietary protein.]
- Possibly causes an overgrowth of gastric bacteria and yeast (candida)
because of the loss of the normally inhibitory effects of HCl acid on
gastric bacterial growth.
Advantages of Sucralfate in the Treatment of Acid-Related Disorders✔✔
ANSWER✔✔No absorption; minimizes systemic adverse effects
- No real contraindications
- Can be used therapeutically and "prophylactically"; as a prophylactic
drug,
,2|Page
___ will not prevent ulceration but will be present as soon as an ulcer
begins to form and prevent it from worsening.
Disadvantages of Sucralfate in the Treatment of Acid-Related
Disorders✔✔ ANSWER✔✔Binds to and prevents the absorption of
some other orally administered drugs; capable of causing an inhibitory
pharmacokinetic drug-drug interaction
- Can be inhibited by other acid-suppressing drugs; ___requires acid to
activate, and must be given at least 1 hour before (preferably two hrs.)
the administration of antacids.
- May cause constipation; this is an aluminum-induced effect and is also
caused by the binding by ___ of bile salts. [Note: Those bile salts which
escape reabsorption by the enterohepatic circuit will stimulate
peristalsis in the colon when they come in contact with the colonic
mucosa.]
- Requires precaution in patients with renal insufficiency; excessive
dosing may cause hyperaluminemia. Aluminum can only be excreted by
renal mechanisms, which requires good kidney function.
Advantages of Misoprostol in the Treatment of Acid-Related
Disorders✔✔ ANSWER✔✔Has dual mechanisms of action; production
of gastric mucus and slight suppression of gastric acid.
- Most advantageous as a blocker of the harmful effects of aspirin and
other NSAIDs on the gastric mucosa.
- Available in a combination product with an NSAID drug [diclofenac +
___ (Arthrotec)]; this simplifies drug administration for those patients
who desire to take one tablet instead of two.
,3|Page
Disadvantages of Misoprostol in the Treatment of Acid-Related
Disorders✔✔ ANSWER✔✔Requires precaution in patients with renal
insufficiency
- Contraindicated in pregnancy; it is a potent stimulant of uterine
contraction and can precipitate premature labor. It can be used as an
abortifacient drug in the first trimester.
___ is commonly used in obstetrics as a labor inducer at delivery time.
This use does not fall into the Pregnancy Category because it is
administered at an appropriate time to cause uterine contractions
deliberately.]
- Limitation of use in childbearing-aged females. Pregnancy tests are
required in this group
- Not effective as monotherapy for acid-related diseases; only used to
offset the harmful effects of the NSAIDs on the gastric mucosa.
- May cause diarrhea and abdominal pain.
- Available orally (tablets, capsules, suspension) and IV
-The least sedating drug to treat seizures of any type.✔✔
ANSWER✔✔Advantages of Phenytoin (Dilantin) in tx of epilepsy
- May cause various CNS adverse reactions
- Can produce a rash; the drug should be discontinued, and if the rash is
severe,___ is contraindicated after that.
, 4|Page
- Long-term therapy can produce cosmetic problems; acne, hirsutism,
coarsening of facial features, gingival hyperplasia
- Can produce lymphadenopathy; Can cause hyperglycemia
- Teratogenic in pregnancy (Pregnancy category D)
- Narrow therapeutic window
- Many drug interactions
-Baseline CBC, urinalysis, and liver function tests should be completed
before beginning therapy.✔✔ ANSWER✔✔Disadvantages of Phenytoin
(Dilantin) in tx of epilepsy
- Useful in pain management of trigeminal neuralgia
- Does not produce sedation in normal dosages
- May also be used in the treatment of bipolar disorder✔✔
ANSWER✔✔Advantages of Carbamazepine (Tegretol) in tx of epilepsy
Commonly causes dizziness, diplopia, and ataxia; usually upon initiation
of therapy
- Rare but severe cases of aplastic anemia and agranulocytosis;
- Can provoke N/V early in therapy
- May cause an erythematous skin rash
- May decrease the serum levels of other anticonvulsants since it is a P-
450 enzyme inducer.
- Cannot be abruptly discontinued;
