NURS 5334 QUIZ 1 |
PHARMACOLOGY |
STUDY GUIDE |
100% VERIFIED
VERSION
PCN drug-drug interactions - -aminoglycosides
-bacteriostatic antibiotics
-probenecid
Cephalosporin Generation 1 - -cephalexin
, -cephazolin
-cephadoxil
Cephalosporin and PCN - Cross allergy w/PCN
Carbapenems - not active against MRSA
Vancomycin treats - gram positive
Vancomycin AE - ototoxicity, nephrotoxicity, red man syndrome
Vancomycin main danger - Hosp/vent. pneumonia in pt w/ Crcl less than 50 as it
increases mortality
Monobactams treats - gram negative aerobic
Fosfomycin treats - enterococcus and Ecoli
Aminoglycosides treat - gram negative bacilli
Aminoglycosides adverse effects - ototoxicity and nephrotoxicity
aminoglycosides peak and trough - Peak: 30 min after IV or IM
Trough: divided- before next dose, daily-1 hr before next dose (value should be low: like
zero)
Sulfonamides MOA - inhibit folic acid synthesis
UTI drugs - 1) TMP/SMZ and nitrofurantoin
2) levofloxacin & ciprofloxacin
UTI in pregnancy - TMP/SMZ, Cipro, Levo, augmentin, cephalexin
recurrent UTI prophylaxis - TMP
Recurrent UTI other tx - SMZ 3 x week for 6 months; TMP or nitro at bedtime for 6 mos.
Acute Bact Prostatitis Tx - Floxacins
Tetracycline adverse effects - -Yellow/brown discoloration of teeth
-hepatotoxicity
-photosensitivity
-GI
-suprainfection/superinfection
tetracycline absorption is impaired by - -magnesium laxative
PHARMACOLOGY |
STUDY GUIDE |
100% VERIFIED
VERSION
PCN drug-drug interactions - -aminoglycosides
-bacteriostatic antibiotics
-probenecid
Cephalosporin Generation 1 - -cephalexin
, -cephazolin
-cephadoxil
Cephalosporin and PCN - Cross allergy w/PCN
Carbapenems - not active against MRSA
Vancomycin treats - gram positive
Vancomycin AE - ototoxicity, nephrotoxicity, red man syndrome
Vancomycin main danger - Hosp/vent. pneumonia in pt w/ Crcl less than 50 as it
increases mortality
Monobactams treats - gram negative aerobic
Fosfomycin treats - enterococcus and Ecoli
Aminoglycosides treat - gram negative bacilli
Aminoglycosides adverse effects - ototoxicity and nephrotoxicity
aminoglycosides peak and trough - Peak: 30 min after IV or IM
Trough: divided- before next dose, daily-1 hr before next dose (value should be low: like
zero)
Sulfonamides MOA - inhibit folic acid synthesis
UTI drugs - 1) TMP/SMZ and nitrofurantoin
2) levofloxacin & ciprofloxacin
UTI in pregnancy - TMP/SMZ, Cipro, Levo, augmentin, cephalexin
recurrent UTI prophylaxis - TMP
Recurrent UTI other tx - SMZ 3 x week for 6 months; TMP or nitro at bedtime for 6 mos.
Acute Bact Prostatitis Tx - Floxacins
Tetracycline adverse effects - -Yellow/brown discoloration of teeth
-hepatotoxicity
-photosensitivity
-GI
-suprainfection/superinfection
tetracycline absorption is impaired by - -magnesium laxative
