NURP 424- Integumentary Exam
With Complete Solution
Types of Acne - Answer Mild Comedonal - includes open (blackheads) & closed
(whiteheads)
Mild to Moderate Inflammatory Acne - includes papules, pustules or both
Moderate to Severe - includes nodules & cysts
Benzoyl Peroxide Form & Indications - Answer OTC Topical Abx (neutrogena, dryox, etc)
Lotions, cream, liquid
Applied 1-2 times daily after cleansing skin
Tx: antibacterial effects vs. P.acnes the main organism in sebaceous follicles &
comedones of acne vulgaris
Side Effects from Benzoyl Peroxide - Answer Drying effect that causes comedolysis with
mild desquamation effect that irritates skin
Patient Considerations for Benzoyl Peroxide - Answer Topical application is safe in
pregnancy
Use in children older than 12 years
Do not administer with Tretinoin because it inactivates the medication
Benzoyl Peroxide /Erythromycin - Answer Topical abx (Benzamycin)
Form: Gel
Works against P. acnes
Adverse Effects from Benzoyl Peroxide/Erythromycin - Answer Skin irritation
Sun sensitivity
Patient Considerations: Benzoyl Peroxide/Erythromycin - Answer Gel dries crusty with
white appearance so may prefer nighttime application.
Can use benzoyl peroxide OTC in the morning
Must be refrigerated (expires 3 months after mixing)
May use in pregnancy if benefits outweigh risks.
, Clindamycin Class, Forms & MOA - Answer Topical Abx
Forms: Gel
MOA: Inhibits P. acnes in vitro preventing synthesis
Clindamycin Contraindications - Answer Chrons
Ulcerative Colitis
Considerations for Clindamycin Prescribing - Answer Caution in those with eczema
Relatively safe in pregnancy
Safe in kids over 12 years
Adverse Effects from Clindamycin - Answer Skin dryness, irritation, burning & peeling
If diarrhea develops stop immediately bc risk for colitis
Azelaic Acid Use, Forms & MOA - Answer Class: Topical Abx
Use: Acne vulgaris & Pustular rosacea
Forms: Gel & Foam
MOA: Decreases inflammation by decreasing bacterial concentrations on skin & has an
anticomedonal effect. It does not effect sebum excretion.
Prescribing considerations for Azelaic acid - Answer If no improvement by 12 weeks-
reassess for use
Erythromycin Tx, Form & MOA - Answer Topical Abx
Forms: Solution, gel & ointment
MOA: Interferes with protein synthesis
Apply BID after washing face with mild cleanser
Erythromycin Prescribing Considerations - Answer Safe in Pregnancy
Do not use concurrently with Clindamycin
Benzoyl Peroxide/Erythromycin TX, Form & MOA - Answer Topical Abx (Benzamycin)
Form: Gel
MOA: Works against P. acnes
Prescribing Considerations for Benzoyl Peroxide/Erythromycin - Answer Not considered
safe in pregnancy
With Complete Solution
Types of Acne - Answer Mild Comedonal - includes open (blackheads) & closed
(whiteheads)
Mild to Moderate Inflammatory Acne - includes papules, pustules or both
Moderate to Severe - includes nodules & cysts
Benzoyl Peroxide Form & Indications - Answer OTC Topical Abx (neutrogena, dryox, etc)
Lotions, cream, liquid
Applied 1-2 times daily after cleansing skin
Tx: antibacterial effects vs. P.acnes the main organism in sebaceous follicles &
comedones of acne vulgaris
Side Effects from Benzoyl Peroxide - Answer Drying effect that causes comedolysis with
mild desquamation effect that irritates skin
Patient Considerations for Benzoyl Peroxide - Answer Topical application is safe in
pregnancy
Use in children older than 12 years
Do not administer with Tretinoin because it inactivates the medication
Benzoyl Peroxide /Erythromycin - Answer Topical abx (Benzamycin)
Form: Gel
Works against P. acnes
Adverse Effects from Benzoyl Peroxide/Erythromycin - Answer Skin irritation
Sun sensitivity
Patient Considerations: Benzoyl Peroxide/Erythromycin - Answer Gel dries crusty with
white appearance so may prefer nighttime application.
Can use benzoyl peroxide OTC in the morning
Must be refrigerated (expires 3 months after mixing)
May use in pregnancy if benefits outweigh risks.
, Clindamycin Class, Forms & MOA - Answer Topical Abx
Forms: Gel
MOA: Inhibits P. acnes in vitro preventing synthesis
Clindamycin Contraindications - Answer Chrons
Ulcerative Colitis
Considerations for Clindamycin Prescribing - Answer Caution in those with eczema
Relatively safe in pregnancy
Safe in kids over 12 years
Adverse Effects from Clindamycin - Answer Skin dryness, irritation, burning & peeling
If diarrhea develops stop immediately bc risk for colitis
Azelaic Acid Use, Forms & MOA - Answer Class: Topical Abx
Use: Acne vulgaris & Pustular rosacea
Forms: Gel & Foam
MOA: Decreases inflammation by decreasing bacterial concentrations on skin & has an
anticomedonal effect. It does not effect sebum excretion.
Prescribing considerations for Azelaic acid - Answer If no improvement by 12 weeks-
reassess for use
Erythromycin Tx, Form & MOA - Answer Topical Abx
Forms: Solution, gel & ointment
MOA: Interferes with protein synthesis
Apply BID after washing face with mild cleanser
Erythromycin Prescribing Considerations - Answer Safe in Pregnancy
Do not use concurrently with Clindamycin
Benzoyl Peroxide/Erythromycin TX, Form & MOA - Answer Topical Abx (Benzamycin)
Form: Gel
MOA: Works against P. acnes
Prescribing Considerations for Benzoyl Peroxide/Erythromycin - Answer Not considered
safe in pregnancy
