Nurs 663-- Pharmacology
Lecture 2 (Quiz 1) questions
and answers
What is a substance released from a nerve and interacts with a
receptor to cause a clinical effect?
neurotransmitter
True/False: there are two systems that which work opposite of each
other and in order to maximize a clinical outcome. NPs often use an
agent which enhances the effects of the neurotransmitter with an
agent that blocks the other system transmitter.
True
What are the parts of peripheral nervous system?
1. Ganglion (autonomic)
2. Adrenergic (sympathetic) & cholinergic (parasympathetic)
3. Skeletal muscle (somatic)
What are the 3 basic steps of neuron activity?
1. conduction of action potentials
2. Neurotransmitter release from axon terminal into system
3. Neurotransmitter binds to post synaptic receptor
What is responsible for transmitting electrical conduction to the end
of the nerve?
the axon
what is the inflow and outflow of ions through membrane channels?
electrical conduction
true/false: few drugs work by affecting the conduction. examples
include local and general anesthetics
true
What term is the potential for more selective effect of medications
by affecting a specific transmitter or a specific receptor?
, neurotransmitter release
what are some examples of post synaptic receptors that
neurotransmitters activate?
Organs, muscle, secretory glands, endocrine glands, neurons
what is the first step of synaptic transmission that provides cursors
molecules to increase the production of a neurotransmitter?
Synthesis
the second step of synaptic transmission that involves the vesicles
being a storage container that is located at the axon terminal
Storage of neurotransmitter
the third step of synaptic transmission where vesicles move to the
end of the nerve and each action potential releases only a small
amount of neurotransmitter
release
the fourth step of synaptic transmission where neurotransmitters
cross the synaptic gap and bind with the receptor. this is the stage
when the drugs start to work.
Receptor Binding
the fifth step of synaptic transmission where the neurotransmitter
disassociates from the receptor?
termination
How can unbound transmitters be removed from the body?
1. reuptake by releasing the nerve
2. enzymatic degradation
3. diffusion
what is a drug that mimics or increases the action of a natural
neurotransmitter either by directly binding to the receptor or by
increasing the levels of the neurotransmitters?
agonist
what is a drug that decreases or blocks the action of a
neurotransmitter?
antagonist
Lecture 2 (Quiz 1) questions
and answers
What is a substance released from a nerve and interacts with a
receptor to cause a clinical effect?
neurotransmitter
True/False: there are two systems that which work opposite of each
other and in order to maximize a clinical outcome. NPs often use an
agent which enhances the effects of the neurotransmitter with an
agent that blocks the other system transmitter.
True
What are the parts of peripheral nervous system?
1. Ganglion (autonomic)
2. Adrenergic (sympathetic) & cholinergic (parasympathetic)
3. Skeletal muscle (somatic)
What are the 3 basic steps of neuron activity?
1. conduction of action potentials
2. Neurotransmitter release from axon terminal into system
3. Neurotransmitter binds to post synaptic receptor
What is responsible for transmitting electrical conduction to the end
of the nerve?
the axon
what is the inflow and outflow of ions through membrane channels?
electrical conduction
true/false: few drugs work by affecting the conduction. examples
include local and general anesthetics
true
What term is the potential for more selective effect of medications
by affecting a specific transmitter or a specific receptor?
, neurotransmitter release
what are some examples of post synaptic receptors that
neurotransmitters activate?
Organs, muscle, secretory glands, endocrine glands, neurons
what is the first step of synaptic transmission that provides cursors
molecules to increase the production of a neurotransmitter?
Synthesis
the second step of synaptic transmission that involves the vesicles
being a storage container that is located at the axon terminal
Storage of neurotransmitter
the third step of synaptic transmission where vesicles move to the
end of the nerve and each action potential releases only a small
amount of neurotransmitter
release
the fourth step of synaptic transmission where neurotransmitters
cross the synaptic gap and bind with the receptor. this is the stage
when the drugs start to work.
Receptor Binding
the fifth step of synaptic transmission where the neurotransmitter
disassociates from the receptor?
termination
How can unbound transmitters be removed from the body?
1. reuptake by releasing the nerve
2. enzymatic degradation
3. diffusion
what is a drug that mimics or increases the action of a natural
neurotransmitter either by directly binding to the receptor or by
increasing the levels of the neurotransmitters?
agonist
what is a drug that decreases or blocks the action of a
neurotransmitter?
antagonist
