ACLAM Written Mock Exam – 2024/25
With complete solution Latest | 100%
verified correct
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A zebra finch colony, Taenopygia gutttata castonotis, has had an increased number of
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colony deaths. Clinical signs varied from none to death, and some birds had gross
ll ll ll ll ll ll ll ll ll
ulceration of the proventriculus and ventriculus. Histopathology using Gomori
ll ll ll ll ll ll ll ll ll ll ll
methenamine silver and Periodic Acid Schiff stain showed clumps of anamorphic
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ascomycetous yeast. What is the likely genus and species of the yeast?
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a. Candida albicans
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b. Macrorhabdus ornithogaster
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c. Saccromyces cerevesiae
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d. Malassezia avies
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e. Albatrellus ovinus
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b. Macrorhabdus ornithogaster ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll
When alpha2-agonists are used alone or as part of a sedation protocol, what are the 2
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common undesirable effects?
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a. Cardiovascular and respiratory depression
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b. Muscular relaxation and GI stasis
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c. Pallor and ptyalism
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d. Seizure and vomiting
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e. Hyperexcitation phase and aggression
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a. Cardiovascular and respiratory depression
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In the formation of the BXD-1/Ty recombinant inbred strain of mice, a _______ female was
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mated to a _______ male.
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a. BALB/c; CD-1
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b. BALB/c; DBA/2J
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c. C57BL/6J; CD-1
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d. C57BL/6J; DBA/2J
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e. DBA/2J; C57BL/6J
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d. C57BL/6J; DBA/2J ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll
According the The Guide for the Care and Use of Laboratory Animals, what is the typical
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housing density for zebrafish?
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a. 1 adult per liter
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b. 2 adults per liter
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c. 5 adults per liter
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d. 10 adults per liter
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c. 5 adults per liter
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For which of the following durations must research facilities that obtain dogs and cats from
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sources other than dealers, exhibitors and exempt persons, hold the animal, not including
,ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll
the day of acquisition or time in transit, before the animal can be used by the facility?
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a. 3 days
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b. 5 days
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c. 7 days
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d. 10 days
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b. 5 days ll ll ll ll ll ll ll ll ll ll ll ll
What organization was the first to develop guidelines for education and training in
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laboratory animal medicine and is still a significant resource used today when it comes to
ll ll ll ll ll ll ll ll ll ll ll ll ll ll
identifying practices that provide for excellence in the welfare of animals used in research,
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education, testing, and the production of pharmaceuticals?
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a. ILAR
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b. AAALAC International
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c. AALAS
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d. ACLAM
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e. ICLAS
ll
a. ILAR ll ll ll ll ll ll ll ll ll ll ll ll ll ll
Due to the inability to excrete sterols, rabbits have been used as model for arthrosclerosis
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by changing what dietary supplement?
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a. Calcium
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b. Cholesterol
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c. Vitamin A
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d. Vitamin B
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b. Cholesterol ll ll ll ll ll ll ll ll ll ll ll
__________ are highly susceptible to Plasmodium vivax, making them an excellent model
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for the human disease and its treatment.
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a. Sanguinus spp.
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b. Callithrix spp.
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c. Aotus spp.
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d. Chlorocebus spp.
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e. Papio spp.
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c. Aotus spp. ll ll ll ll ll ll ll ll ll ll ll ll ll ll
What is the effect of continuous lighting on the reproductive cycle of mice and rats?
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a. Cessation of cycling due to lengthening and persistence of cycles
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b. "Fixing" of cycles in anestrus phase
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c. It has no significant effect
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d. Shortening of cycles and increased reproductive performance
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a. Cessation of cycling due to lengthening and persistence of cycles
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Dealers, exhibitors, and research facilities must develop a plan for environmental
ll ll ll ll ll ll ll ll ll ll ll
enhancement to promote the psychological well-being of non-human primates. Unless the
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condition is permanent, exemptions to this plan must be documented and reviewed:
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a. By the Attending Veterinarian, every 30 days
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b. By the Attending Veterinarian, every 60 days
ll ll ll ll ll ll ll
c. By the Attending Veterinarian, every 90 days
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d. By the Attending Veterinarian, semi-annually
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e. By the Attending Veterinarian, annually
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a. By the Attending Veterinarian, every 30 days
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What are the most frequent infective causative agents of lameness in a sheep herd?
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a. Campylobacter fetus and Clostridium perfringens
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b. Dermatophilis congolensis and Mannheimia hemolytica
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c. Dichelobacter nodosus and Fusobacterium necrophorum
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d. Fusobacterium necrophorum and Listeria monocytogenes
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c. Dichelobacter nodosus and Fusobacterium necrophorum
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Which of the following is considered to be the postoperative opioid analgesic of choice for
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swine?
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a. Fentanyl
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b. Morphine
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c. Buprenorphine
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d. Carprofen
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e. Aspirin
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c. Buprenorphine
AD
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Which of the following organisms are resistant to the effects of peracetic acid?
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a. Clostridial spores and Mycobacterium species
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b. Clostridial spores and parasite cysts
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c. Mycobacterium species and arthropod eggs
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d. Parasite cysts and arthropod eggs
ll ll ll ll ll
e. Parasite cysts and Mycobacterium species
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d. Parasite cysts and arthropod eggs
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Which of the following statements best describes use of vaporized hydrogen peroxide in
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research facilities?
ll ll ll ll ll ll ll ll ll
a. Limited use for decontamination of electronic or medical devices
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b. Low-temperature sterilant
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c. Not compatible with many materials
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d. Used for decontamination of unsealed enclosures
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b. Low-temperature sterilant
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Per the AWA, how many 3 kg rabbits can be housed together in a pen measuring 36x24x15
ll
inches?
ll
a. 0 ll
b. 1 ll
c. 2 ll
d. 3 ll
e. 4 ll
c. 2 ll ll ll ll ll ll ll ll ll ll ll ll ll
Which of the following is the most common neoplasm found in aged Sprague-Dawley rats?
, ll ll ll ll
a. Large granular lymphocytic tumors
ll ll ll ll ll
b. Mammary gland tumors (benign fibroadenomas)
ll ll ll ll
c. Pancreatic islet cell tumors
ll ll ll ll ll
d. Pituitary tumors (pars distalis adenomas)
ll ll ll ll ll
e. Testicular tumors (interstitial cell tumors)
ll ll ll ll ll
b. Mammary gland tumors (benign fibroadenomas)
ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll
What rodent serves as a model for Hepatitis B virus when infected with a similar species-
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specific virus?
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a. Heterocephalus glaber
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b. Marmota monax
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c. Cynomys lydovicianus
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d. Dipodomys spectabilis
ll ll
e. Peromyscus leucopus
ll ll
b. Marmota monax ll ll ll ll ll ll ll ll ll ll ll ll ll
Which of the following methods for water disinfection is associated with the formation of
ll ll ll ll ll ll
trihalomethanes when water contains organic compounds?
ll
a. Acidification
ll
b. Autoclaving
ll
c. Chlorination
ll ll
d. Ozone disinfection
ll
c. Chlorination
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Mice infected with Leptospira should be handled using ________ practices.
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a. BSL-1
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b. BSL-2
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c. BSL-2 enhanced
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d. BSL-3
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e. BSL-4
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b. BSL-2 ll ll ll ll ll ll ll ll ll ll ll
Koplik spots are pathognomonic for which of the following etiologies in macaques?
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a. Measles virus
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b. Metapneumovirus
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c. Parainfluenza virus
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d. Paramyxovirus saguinus
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e. Respiratory syncytial virus
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a. Measles virus ll ll ll ll ll ll ll ll ll ll
Which of the following analgesics is a DEA schedule IV drug?
ll
a. Buprenorphine
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b. Butorphanol
ll
c. Fentanyl
ll
d. Hydromorphone
ll
b. Butorphanol ll ll ll ll ll ll ll ll ll ll ll
Which of the following imaging techniques requires the use of radio-labeled probes?
With complete solution Latest | 100%
verified correct
ll ll ll ll ll ll ll ll ll ll ll ll
A zebra finch colony, Taenopygia gutttata castonotis, has had an increased number of
ll ll ll ll ll ll ll ll ll ll ll ll ll ll
colony deaths. Clinical signs varied from none to death, and some birds had gross
ll ll ll ll ll ll ll ll ll
ulceration of the proventriculus and ventriculus. Histopathology using Gomori
ll ll ll ll ll ll ll ll ll ll ll
methenamine silver and Periodic Acid Schiff stain showed clumps of anamorphic
ll ll ll ll ll ll ll ll ll ll ll ll
ascomycetous yeast. What is the likely genus and species of the yeast?
ll ll
a. Candida albicans
ll ll
b. Macrorhabdus ornithogaster
ll ll
c. Saccromyces cerevesiae
ll ll
d. Malassezia avies
ll ll
e. Albatrellus ovinus
ll ll
b. Macrorhabdus ornithogaster ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll
When alpha2-agonists are used alone or as part of a sedation protocol, what are the 2
ll ll ll
common undesirable effects?
ll ll ll ll
a. Cardiovascular and respiratory depression
ll ll ll ll ll
b. Muscular relaxation and GI stasis
ll ll ll
c. Pallor and ptyalism
ll ll ll
d. Seizure and vomiting
ll ll ll ll
e. Hyperexcitation phase and aggression
ll ll ll ll
a. Cardiovascular and respiratory depression
ll ll ll ll ll ll ll ll ll ll ll ll ll ll
In the formation of the BXD-1/Ty recombinant inbred strain of mice, a _______ female was
ll ll ll ll ll
mated to a _______ male.
ll ll
a. BALB/c; CD-1
ll ll
b. BALB/c; DBA/2J
ll ll
c. C57BL/6J; CD-1
ll ll
d. C57BL/6J; DBA/2J
ll ll
e. DBA/2J; C57BL/6J
ll ll
d. C57BL/6J; DBA/2J ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll
According the The Guide for the Care and Use of Laboratory Animals, what is the typical
ll ll ll ll
housing density for zebrafish?
ll ll ll ll
a. 1 adult per liter
ll ll ll ll
b. 2 adults per liter
ll ll ll ll
c. 5 adults per liter
ll ll ll ll
d. 10 adults per liter
ll ll ll ll
c. 5 adults per liter
ll ll ll ll ll ll ll ll ll ll ll ll ll ll
For which of the following durations must research facilities that obtain dogs and cats from
ll ll ll ll ll ll ll ll ll ll ll ll ll
sources other than dealers, exhibitors and exempt persons, hold the animal, not including
,ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll
the day of acquisition or time in transit, before the animal can be used by the facility?
ll ll
a. 3 days
ll ll
b. 5 days
ll ll
c. 7 days
ll ll
d. 10 days
ll ll
b. 5 days ll ll ll ll ll ll ll ll ll ll ll ll
What organization was the first to develop guidelines for education and training in
ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll
laboratory animal medicine and is still a significant resource used today when it comes to
ll ll ll ll ll ll ll ll ll ll ll ll ll ll
identifying practices that provide for excellence in the welfare of animals used in research,
ll ll ll ll ll ll ll
education, testing, and the production of pharmaceuticals?
ll
a. ILAR
ll ll
b. AAALAC International
ll
c. AALAS
ll
d. ACLAM
ll
e. ICLAS
ll
a. ILAR ll ll ll ll ll ll ll ll ll ll ll ll ll ll
Due to the inability to excrete sterols, rabbits have been used as model for arthrosclerosis
ll ll ll ll ll
by changing what dietary supplement?
ll
a. Calcium
ll
b. Cholesterol
ll ll
c. Vitamin A
ll ll
d. Vitamin B
ll
b. Cholesterol ll ll ll ll ll ll ll ll ll ll ll
__________ are highly susceptible to Plasmodium vivax, making them an excellent model
ll ll ll ll ll ll ll
for the human disease and its treatment.
ll ll
a. Sanguinus spp.
ll ll
b. Callithrix spp.
ll ll
c. Aotus spp.
ll ll
d. Chlorocebus spp.
ll ll
e. Papio spp.
ll ll
c. Aotus spp. ll ll ll ll ll ll ll ll ll ll ll ll ll ll
What is the effect of continuous lighting on the reproductive cycle of mice and rats?
ll ll ll ll ll ll ll ll ll ll
a. Cessation of cycling due to lengthening and persistence of cycles
ll ll ll ll ll ll
b. "Fixing" of cycles in anestrus phase
ll ll ll ll ll
c. It has no significant effect
ll ll ll ll ll ll ll
d. Shortening of cycles and increased reproductive performance
ll ll ll ll ll ll ll ll ll ll
a. Cessation of cycling due to lengthening and persistence of cycles
ll ll ll ll ll ll ll ll ll ll
Dealers, exhibitors, and research facilities must develop a plan for environmental
ll ll ll ll ll ll ll ll ll ll ll
enhancement to promote the psychological well-being of non-human primates. Unless the
ll ll ll ll ll ll ll ll ll ll ll ll
condition is permanent, exemptions to this plan must be documented and reviewed:
ll ll ll ll ll ll ll
a. By the Attending Veterinarian, every 30 days
, ll ll ll ll ll ll ll
b. By the Attending Veterinarian, every 60 days
ll ll ll ll ll ll ll
c. By the Attending Veterinarian, every 90 days
ll ll ll ll ll
d. By the Attending Veterinarian, semi-annually
ll ll ll ll ll
e. By the Attending Veterinarian, annually
ll ll ll ll ll ll ll
a. By the Attending Veterinarian, every 30 days
ll ll ll ll ll ll ll ll ll ll ll ll ll
What are the most frequent infective causative agents of lameness in a sheep herd?
ll ll ll ll ll
a. Campylobacter fetus and Clostridium perfringens
ll ll ll ll ll
b. Dermatophilis congolensis and Mannheimia hemolytica
ll ll ll ll ll
c. Dichelobacter nodosus and Fusobacterium necrophorum
ll ll ll ll ll
d. Fusobacterium necrophorum and Listeria monocytogenes
ll ll ll ll ll
c. Dichelobacter nodosus and Fusobacterium necrophorum
ll ll ll ll ll ll ll ll ll ll ll ll ll ll
Which of the following is considered to be the postoperative opioid analgesic of choice for
ll
swine?
ll
a. Fentanyl
ll
b. Morphine
ll
c. Buprenorphine
ll
d. Carprofen
ll
e. Aspirin
ll
c. Buprenorphine
AD
ll ll ll ll ll ll ll ll ll ll ll ll
Which of the following organisms are resistant to the effects of peracetic acid?
ll ll ll ll ll
a. Clostridial spores and Mycobacterium species
ll ll ll ll ll
b. Clostridial spores and parasite cysts
ll ll ll ll ll
c. Mycobacterium species and arthropod eggs
ll ll ll ll ll
d. Parasite cysts and arthropod eggs
ll ll ll ll ll
e. Parasite cysts and Mycobacterium species
ll ll ll ll ll
d. Parasite cysts and arthropod eggs
ll ll ll ll ll ll ll ll ll ll ll ll
Which of the following statements best describes use of vaporized hydrogen peroxide in
ll ll
research facilities?
ll ll ll ll ll ll ll ll ll
a. Limited use for decontamination of electronic or medical devices
ll ll
b. Low-temperature sterilant
ll ll ll ll ll
c. Not compatible with many materials
ll ll ll ll ll ll
d. Used for decontamination of unsealed enclosures
ll ll
b. Low-temperature sterilant
ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll
Per the AWA, how many 3 kg rabbits can be housed together in a pen measuring 36x24x15
ll
inches?
ll
a. 0 ll
b. 1 ll
c. 2 ll
d. 3 ll
e. 4 ll
c. 2 ll ll ll ll ll ll ll ll ll ll ll ll ll
Which of the following is the most common neoplasm found in aged Sprague-Dawley rats?
, ll ll ll ll
a. Large granular lymphocytic tumors
ll ll ll ll ll
b. Mammary gland tumors (benign fibroadenomas)
ll ll ll ll
c. Pancreatic islet cell tumors
ll ll ll ll ll
d. Pituitary tumors (pars distalis adenomas)
ll ll ll ll ll
e. Testicular tumors (interstitial cell tumors)
ll ll ll ll ll
b. Mammary gland tumors (benign fibroadenomas)
ll ll ll ll ll ll ll ll ll ll ll ll ll ll ll
What rodent serves as a model for Hepatitis B virus when infected with a similar species-
ll
specific virus?
ll ll
a. Heterocephalus glaber
ll ll
b. Marmota monax
ll ll
c. Cynomys lydovicianus
ll ll
d. Dipodomys spectabilis
ll ll
e. Peromyscus leucopus
ll ll
b. Marmota monax ll ll ll ll ll ll ll ll ll ll ll ll ll
Which of the following methods for water disinfection is associated with the formation of
ll ll ll ll ll ll
trihalomethanes when water contains organic compounds?
ll
a. Acidification
ll
b. Autoclaving
ll
c. Chlorination
ll ll
d. Ozone disinfection
ll
c. Chlorination
ll ll ll ll ll ll ll ll ll
Mice infected with Leptospira should be handled using ________ practices.
ll
a. BSL-1
ll
b. BSL-2
ll ll
c. BSL-2 enhanced
ll
d. BSL-3
ll
e. BSL-4
ll
b. BSL-2 ll ll ll ll ll ll ll ll ll ll ll
Koplik spots are pathognomonic for which of the following etiologies in macaques?
ll ll
a. Measles virus
ll
b. Metapneumovirus
ll ll
c. Parainfluenza virus
ll ll
d. Paramyxovirus saguinus
ll ll ll
e. Respiratory syncytial virus
ll ll
a. Measles virus ll ll ll ll ll ll ll ll ll ll
Which of the following analgesics is a DEA schedule IV drug?
ll
a. Buprenorphine
ll
b. Butorphanol
ll
c. Fentanyl
ll
d. Hydromorphone
ll
b. Butorphanol ll ll ll ll ll ll ll ll ll ll ll
Which of the following imaging techniques requires the use of radio-labeled probes?
