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PMCOL 200 - GI EXAM LATEST UPDATE

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PMCOL 200 - GI EXAM LATEST
UPDATE

gastric diseases - Answer peptic ulcers

gastrogesophageal reflux disease

nausea and vomiting

gastrointestinal motility problems

acid peptic disorder - Answer group of disorders involving either excessive acid
secretion or erosion of the mucous lining

includes GERD and peptic ulcers

what is the target of drugs used to help acid peptic diseases - Answer manipulate acid
secretion

promote mucosa defense

get rid of helicobacter pylori

the stomach compartments - Answer antrum and fundus

parietal cells - Answer found in the fundus responsible for secretion of HCl

how is acid secreted from the parietal cells - Answer H/K ATP pump moves acid from
parietal cell to gastric lumen

What is carbonic anhydrase? - Answer RBC enzymes that catalyze the rapid
interconversion of carbon dioxide and water to bicarbonate and H+ ions. This
conversion is normally slow in the plasma but CA causes the conversion to occur
rapidly.

G cells - Answer found in the antrum

secrete gastrin

what does gastrin bind to - Answer CCK receptors on parietal cells

what cells do gastrin stimulate - Answer ECL cells

which release hsitamine from H2 receptors

vagus nerve and the enteric nervous system - Answer post-ganglionic neurons of the

, enteric nervous system release acetylcholine which bind to M3 receptors on parietal
cells

D cells - Answer release somatostain

inhibit gastrin release from G cells

Antacids - Answer weak bases

neutralize stomach acid by reacting with protons in the lumen of the gut

large doses necessary to change the pH of the stomach

two popular antacids - Answer magnesium chlordie

- laxative effects

- increases motility

alluminium hydrozude

- constipation action

- slows motility

nether are absorbed in the gut.

proton pump inhibitors - Answer omeprazole

decrease bioavailabity of B12

omeprazole - Answer lipophillic

weak base

diffuse onto pairetal cells and inactivate the H/K pump which inhibits acid secretion

hypergastrinemia - Answer caused by prolonged use of omeprazole can lead to excess
gastrin in the stomach

- increased risk of cancer

nausea and vomitting - Answer defense againt food poisining

motion sickness

best wa to cure upset stomach - Answer letting the bacteria rid itself from your body

anti emetics - Answer deal with nausea and vomiting caused my motion sicenss

bismuth subsalicylate - Answer Pepto Bismol

hydrlozed into bismuth oxychloride and salicylic acid

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