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Pathophysiology - Module 3 Quiz Questions and Answers Fully Solved

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Pathophysiology - Module 3 Quiz

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Pathophysiology - Module 3 Quiz

Allostasis - answeran adaptive physiologic response to stressful events (i.e., fight or
flight)

"wear and tear on the body as a result of stressful events"

Allostasis involves - answer"stability through change"

In allostasis, the brain continuously monitors for future events and anticipates what is
required from __________________________ and ___________________________
systems - answerneuroendocrine, autonomic

Allostatic overload - answeran exaggerated, pathophysiologic response to stress

Allostatic overload involves overactivation of - answeradaptive systems

Allostatic overload is highly _____________________________ - answerindividualized

Homeostasis - answera biological system's ability to maintain dynamic internal
equilibrium in the face of external or internal changes

"body imbalance"

Physiological responses to stress are processed through - answerSympathetic nervous
system (SNS)

Parasympathetic nervous system (PNS)

Sympathetic nervous system - answer"flight or flight"

produces hormonal and
catecholamine responses

up-regulated during stress

Parasympathetic nervous system - answerdown-regulated during stress

HPA axis - answerHypothalamic-Pituitary-Adrenal axis

Hypothalamus secretes - answercorticotropin-releasing hormone (CRH)

, Pituitary secretes - answeradrenocorticotropic-releasing hormone (ACTH)

Adrenals secrete - answercortisol and catecholamines

Cortisol is secreted during ___________________ and reaches all
__________________ - answerstress, tissues

Cortisol stimulates ______________________________ and elevates blood
_______________________ levels - answergluconeogenesis, glucose

__________________ affects protein metabolism - answerCortisol

Cortisol is a powerful ___________________________ and
___________________________ agent - answeranti-inflammatory,
immunosuppressive

Abnormal elevations of cortisol are linked to - answerObesity
Sleep deprivation
Lipid abnormalities
Hypertension
Diabetes
Artherosclerosis
Loss of bone density

Secretion of cortisol during stress inhibits initial _______________________________
effects - answerinflammatory

Promotes resolution and repair - answercortisol

Cortisol induces T-cell _______________________ - answerapoptosis

Cortisol influences virtually all _____________________ cells - answerimmune

Elevated levels of cortisol may decrease _________________ immunity and increase
_____________________responses - answerinnate, autoimmune

Catecholamines include - answerepinephrine
nonepinephrine

Catecholamines are released from the - answeradrenal medualla

Stimulates two major classes of receptors - answerCatecholamines

Catecholamine receptor types - answera-adrenergic receptors

b-adrenergic receptors

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