NR 566 Pharm final Questions
& Answers(GRADED A)
Doxazosin side effects - ANSWER orthostatic hypotension, falls, reflex tachycardia, headache, and
nasal congestion
Dutasteride patient teaching and response to delayed onset of therapeutic effect - ANSWER o
benefits take months to develop
o decreased ejaculate volume and libido.
o FDA Pregnancy Risk Category X. It can be absorbed through the skin, so pregnant women should
not handle the drug.
o men should not donate blood while using it or for at least 6 months after stopping it to avoid
transmission to women through an infusion
How to know Terazosin is working - ANSWER improved symptoms of dysuria, urgency, urinary tract
infections, hesitancy
Various routes of administration of estrogen therapy and when each would be used - ANSWER o PO
—used more than any other
o Compared with oral formulations, the transdermal formulations have four advantages:
• The total dose of estrogen is greatly reduced (because the liver is bypassed).
• There is less nausea and vomiting.
• Blood levels of estrogen fluctuate less.
• There is a lower risk for DVT, pulmonary embolism, and stroke
o Intravaginal administration—available as tablets, creams, and vaginal rings. They are used only for
local effects, primarily treatment of vulval and vaginal atrophy associated with menopause. The
other vaginal ring [Femring] can also help with systemic effects (i.e. control of hot flashes and night
sweats)
o IV and IM—limited to acute, emergency control of heavy uterine bleeding
, When is it safe and not safe to prescribe progesterone (AKA: progestin) - ANSWER o Safe—
menopausal hormone therapy, dysfunctional uterine bleeding, amenorrhea, endometrial cacer and
hyperplasia
o Not safe—arterial disease, breast cancer, depression
alprostadil benefits of various routes - ANSWER o injection: can be done by patient or in ER setting;
rapidly leads to erection, painless
o intraurethral pellet insertion: can be done by patient, erection occurs within 5-10 mins, minimal
side effects
papaverine plus phentolamine patient education - ANSWER do not inject more than once in a 24 hr
period, notify provider of erection duration and efficacy, do not take other ED meds with this
medication, needle/injection teaching, do not change the dose yourself, seek medical attention if
erection is >3 hrs
How does carbamazepine (Tegretol) impact oral contraceptives and what symptoms may be
associated with that? - ANSWER o accelerates OC metabolism, reducing OC effect
o can lead to abnormal bleeding, return of menstrual symptoms, and of course pregnancy!
How do the affects of carbamazepine (Tegretol) which OCP is prescribed? - ANSWER o increase the
estrogen dosage of the OC
o combine the OC with a second form of birth control
o switch to an alternative form of birth control
First-line treatment for acute, mild to moderate migraine without nausea or vomiting - ANSWER
aspirin, acetaminophen, naproxen, diclofenac, and other aspirin-like analgesics
How to know someone would be appropriate for preventative therapy - ANSWER Indicated for
patients who have frequent attacks (3+ a month), severe attacks, or attacks that do not respond
adequately to abortive therapy
Opioid analgesics reserved for severe migraines that don't respond to first-line medications -
ANSWER butorphanol nasal spray; 1 spray (1 mg) in one nostril; may repeat in 60 min
& Answers(GRADED A)
Doxazosin side effects - ANSWER orthostatic hypotension, falls, reflex tachycardia, headache, and
nasal congestion
Dutasteride patient teaching and response to delayed onset of therapeutic effect - ANSWER o
benefits take months to develop
o decreased ejaculate volume and libido.
o FDA Pregnancy Risk Category X. It can be absorbed through the skin, so pregnant women should
not handle the drug.
o men should not donate blood while using it or for at least 6 months after stopping it to avoid
transmission to women through an infusion
How to know Terazosin is working - ANSWER improved symptoms of dysuria, urgency, urinary tract
infections, hesitancy
Various routes of administration of estrogen therapy and when each would be used - ANSWER o PO
—used more than any other
o Compared with oral formulations, the transdermal formulations have four advantages:
• The total dose of estrogen is greatly reduced (because the liver is bypassed).
• There is less nausea and vomiting.
• Blood levels of estrogen fluctuate less.
• There is a lower risk for DVT, pulmonary embolism, and stroke
o Intravaginal administration—available as tablets, creams, and vaginal rings. They are used only for
local effects, primarily treatment of vulval and vaginal atrophy associated with menopause. The
other vaginal ring [Femring] can also help with systemic effects (i.e. control of hot flashes and night
sweats)
o IV and IM—limited to acute, emergency control of heavy uterine bleeding
, When is it safe and not safe to prescribe progesterone (AKA: progestin) - ANSWER o Safe—
menopausal hormone therapy, dysfunctional uterine bleeding, amenorrhea, endometrial cacer and
hyperplasia
o Not safe—arterial disease, breast cancer, depression
alprostadil benefits of various routes - ANSWER o injection: can be done by patient or in ER setting;
rapidly leads to erection, painless
o intraurethral pellet insertion: can be done by patient, erection occurs within 5-10 mins, minimal
side effects
papaverine plus phentolamine patient education - ANSWER do not inject more than once in a 24 hr
period, notify provider of erection duration and efficacy, do not take other ED meds with this
medication, needle/injection teaching, do not change the dose yourself, seek medical attention if
erection is >3 hrs
How does carbamazepine (Tegretol) impact oral contraceptives and what symptoms may be
associated with that? - ANSWER o accelerates OC metabolism, reducing OC effect
o can lead to abnormal bleeding, return of menstrual symptoms, and of course pregnancy!
How do the affects of carbamazepine (Tegretol) which OCP is prescribed? - ANSWER o increase the
estrogen dosage of the OC
o combine the OC with a second form of birth control
o switch to an alternative form of birth control
First-line treatment for acute, mild to moderate migraine without nausea or vomiting - ANSWER
aspirin, acetaminophen, naproxen, diclofenac, and other aspirin-like analgesics
How to know someone would be appropriate for preventative therapy - ANSWER Indicated for
patients who have frequent attacks (3+ a month), severe attacks, or attacks that do not respond
adequately to abortive therapy
Opioid analgesics reserved for severe migraines that don't respond to first-line medications -
ANSWER butorphanol nasal spray; 1 spray (1 mg) in one nostril; may repeat in 60 min
