ACE inhibitors end in... Correct Answers -pril
(Captopril, Enalapril, Fosinopril, Lisinopril)
Antihypertensives: Diuretics Correct Answers - Thiazide:
Hydrochlorothiazide (Mainstay medication, depletes potassium)
- Potassium Sparing: Spironolactone (Watch potassium level)
Loop: Furosemide (More diuresis, more severe HTN)
ARB's end in ... Correct Answers -sartan
Beta blockers end in... Correct Answers -olol
(Atenolol, Metoprolol, Propranolol)
Calcium Channel Blockers end in.... Correct Answers -dipine
(except Verapamil & Diltiazem)
Cholesterol absorption inhibitor "Ezetimibe" does what?
Correct Answers - Inhibits absorption of cholesterol in small
intestine
- Adjunctive treatment with statin
Elevated BP range Correct Answers 120-129/<80
- Recommend healthy lifestyle changes
- Re-evaluate in 3-6 months
How do beta-blockers work?(adrenergic antagonists) Correct
Answers - Reduce CO which decreases vascular resistance
which decreases BP
- Decreases renin release which decreases BP
, - Hold for hypotension
- Hold for AP<60
How do calcium channel blockers work? Correct Answers -
Calcium channels are found in the myocardium and arterial
smooth muscle. Ca++ increases contractility, peripheral
resistance and BP. These drugs BLOCK these effects.
- Causes smooth muscle relaxation by blocking the binding of
calcium to its receptors, preventing muscle contraction. This
causes decreased peripheral smooth muscle tone and decreased
systemic vascular resistance.
- Result: DECREASED BLOOD PRESSURE
How do you find the MAP? (Mean arterial pressure) Correct
Answers SBP+2(DBP)/3
>60 mmHg = Adequate Perfusion
How does low molecular weight Heparin work? (enoxaparin)
Correct Answers - Inhibit thrombus and clot formation by
blocking factor Xa (anticoagulant)
- More stable than heparin
- D/C if platelets below 100,000
- Antidote: protamine sulfate
- Scientific air bubble inside of syringe
How does wafarin work? Correct Answers - Interferes with
vitamin K clotting factors