Chamberlain NR 293 Pharmacology Exam 1.pdf file:///C:/Users/HP/Desktop/pppppp/Chamberlain%20NR%20293%2
Chamberlain NR 293 Pharmacology Exam 1
1. What is pharmaceutics
ANS The dosage form that determines the rate of drugdissolution
2. What is pharmacodynamics
ANS What the drugs do to the body..therapeutic effects
3. What is pharmacokinetics
ANS What the body does to the drug..movement of drugsthrough the body
4. What is the process of pharmacokinetics
ANS Absorption, distribution, metabolismand excretion
5. List the absorption routes of drugs by mouth from fastest to slowest
ANS Sub-lingual
Liquid Suspension
Capsule
Tablet
Enteric coated tablets
Extended release tablets
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,Chamberlain NR 293 Pharmacology Exam 1.pdf file:///C:/Users/HP/Desktop/pppppp/Chamberlain%20NR%20293%2
6. What type of drugs are absorbed into the GI tract and metabolized by theliver. This
results in a reduce amount of bioavailability or active drug in the circulatory system.
therefor this type of drug has a higher dose to allow forthe effect
ANS Oral drugs
7. What form of drugs are affected by the first pass effect
ANS Elixir, tablets andcapsules
8. What are considered enteral drugs
ANS Elixirs, tablets and capsules
9. What drugs are not affected by the first pass effect
ANS IV, sublingual, transdermalpatch, suppository (parenteral drugs)
10. What is the First Pass Effect
ANS Initial liver metabolism
11. Drugs not affected by first pass effect are considered
ANS parenteral (IV, sub-lingual, transdermal patch and suppositories)
12. What is half life of a drug
ANS The time it takes for half of a drug dose to beeliminated from the body
Ex
200mg ibuprofen has a half life of 2 hours, 100 mg will be remaining in the bodyafter 1 half life
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2 of 18 8/28/2024, 3:22
,Chamberlain NR 293 Pharmacology Exam 1.pdf file:///C:/Users/HP/Desktop/pppppp/Chamberlain%20NR%20293%2
or 2 hours. After 2 half lives (4 hours) only 50 mg will be left etc etc etc
13. Rate of distribution depends on what
ANS Vascular permeability, blood flow andperfusion
14. What is it called when drugs become available to action sites.
Example low levels of albumin and immunigloblins (blood proteins) results in problems
with toxicity because there are fewer binding sites for the drug
ANS Dis-tribution
15. What causes free drugs to float around the body causing toxicity
ANS Lowprotein/Low albumin level
3/6
3 of 18 8/28/2024, 3:22
Chamberlain NR 293 Pharmacology Exam 1
1. What is pharmaceutics
ANS The dosage form that determines the rate of drugdissolution
2. What is pharmacodynamics
ANS What the drugs do to the body..therapeutic effects
3. What is pharmacokinetics
ANS What the body does to the drug..movement of drugsthrough the body
4. What is the process of pharmacokinetics
ANS Absorption, distribution, metabolismand excretion
5. List the absorption routes of drugs by mouth from fastest to slowest
ANS Sub-lingual
Liquid Suspension
Capsule
Tablet
Enteric coated tablets
Extended release tablets
1/6
1 of 18 8/28/2024, 3:22
,Chamberlain NR 293 Pharmacology Exam 1.pdf file:///C:/Users/HP/Desktop/pppppp/Chamberlain%20NR%20293%2
6. What type of drugs are absorbed into the GI tract and metabolized by theliver. This
results in a reduce amount of bioavailability or active drug in the circulatory system.
therefor this type of drug has a higher dose to allow forthe effect
ANS Oral drugs
7. What form of drugs are affected by the first pass effect
ANS Elixir, tablets andcapsules
8. What are considered enteral drugs
ANS Elixirs, tablets and capsules
9. What drugs are not affected by the first pass effect
ANS IV, sublingual, transdermalpatch, suppository (parenteral drugs)
10. What is the First Pass Effect
ANS Initial liver metabolism
11. Drugs not affected by first pass effect are considered
ANS parenteral (IV, sub-lingual, transdermal patch and suppositories)
12. What is half life of a drug
ANS The time it takes for half of a drug dose to beeliminated from the body
Ex
200mg ibuprofen has a half life of 2 hours, 100 mg will be remaining in the bodyafter 1 half life
2/6
2 of 18 8/28/2024, 3:22
,Chamberlain NR 293 Pharmacology Exam 1.pdf file:///C:/Users/HP/Desktop/pppppp/Chamberlain%20NR%20293%2
or 2 hours. After 2 half lives (4 hours) only 50 mg will be left etc etc etc
13. Rate of distribution depends on what
ANS Vascular permeability, blood flow andperfusion
14. What is it called when drugs become available to action sites.
Example low levels of albumin and immunigloblins (blood proteins) results in problems
with toxicity because there are fewer binding sites for the drug
ANS Dis-tribution
15. What causes free drugs to float around the body causing toxicity
ANS Lowprotein/Low albumin level
3/6
3 of 18 8/28/2024, 3:22
