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Chapter 21 General, Organic, and biological Chemistry

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Chapter 21 General, Organic, and biological Chemistry Chapter 21 General, Organic, and biological Chemistry Chapter 21 General, Organic, and biological Chemistry Chapter 21 General, Organic, and biological Chemistry Chapter 21 General, Organic, and biological Chemistry Chapter 21 General, Organic, and biological Chemistry Chapter 21 General, Organic, and biological Chemistry Chapter 21 General, Organic, and biological Chemistry Chapter 21 General, Organic, and biological Chemistry

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Chapter 21 General, Organic, and
biological Chemistry
— GAA — CCC — TTT —

What is the amino acid order in the peptide? - ANSWER-—CUU—GGG—AAA— Leu — Gly — Lys

—CUU—GGG—AAA—

What are the anticodons for the tRNAs? - ANSWER-GAA for CUU; CCC for GGG; UUU for AAA

3' GAA TTT GCT CAA 5'

What happens to the protein synthesis if a point mutation changes the sixth base to Cytosine in the
3' to 5' direction of DNA segment? - ANSWER-Mutated DNA:

3' GAA TTC GCT CAA 5'



mRNA Mutated Peptide

5' CUU AAG CGA GUU 3'



Mutated Peptide:

Leu-Lys-Arg-Val

(Point mutation that is Silent Mutation)

3' GAA TTT GCT CAA 5'

What is the amino acid sequence if a mutation adds a G base at the beginning of DNA segment? -
ANSWER-Mutated DNA:

3' GGA ATT TGC TCA A 5'

m RNA:

5' CCU UAA ACG AGU U 3'

Mutated Peptide:

Pro-STOP

3' GAA TTT GCT CAA 5'

What is the amino acid sequence if a mutation removes a G base from the beginning of DNA
segment? - ANSWER-Mutated DNA:

3' AAT TTG CTC AA 5'

mRNA:

5' UUA AAC GAG UU 3'

Mutated Peptide:

Leu-Asn-Glu

, Chapter 21 General, Organic, and
biological Chemistry
a small particle requiring a host cell to replicate - ANSWER-Virus

a substance that prevents the synthesis of viral proteins - ANSWER-Protease inhibitor

a virus containing RNA - ANSWER-Retrovirus

A virus that contains RNA as its genetic material is a - ANSWER-retrovirus

AIDS Treatment - ANSWER-Treatment for AIDS is based on attacking HIV at different points in its life
cycle, such as prevention of reverse transcription of the

viral DNA and protein synthesis.

Cancer can be caused - ANSWER-by chemical and environmental substances, by ultraviolet or
medical radiation, or by oncogenic viruses, which are associated with human cancers.

Condiser the following segment of normal DNA:

3' GAA TTT GCT CAA 5'



Write the coresponding mRNA segment - ANSWER-5' CUU AAA CGA GUU 3'

contained within the nucleus of the cell the information for the synthesis of protein - ANSWER-DNA

DNA structure - ANSWER-

DNA- pentose sugar - ANSWER-

GAA UUU GCU CAA

What is the amino acids sequence in the peptide that is synthesized? Use the three and one one
letter (separated) abbreviations for the amino acids . - ANSWER-CUU AAA CGU GUU

Leu-Lys-Arg-Val

L-K-R-V

Generally, how does recombinant DNA technology work? - ANSWER-is formed by placing a gene
from another organism in a plasmid DNA of a bacterium such as an E.coli. This causes the bacterium
to produce a nonbacterial protein in large quantities

Identify each of the following bases as a component of DNA, RNA, or both:



Guanine

adenine

thymine

uracil - ANSWER-Guanine-DNA and RNA

adenine-DNA and RNA

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