BIOCHEM CHAPTER 4 EXAM BIOCHEM CHAPTER 4 EXAM
QUESTIONS AND ANSWERS GRADED A+
The role of hormone-sensitive triacylglycerol lipase is to:
A) hydrolyze lipids stored in the liver.
B) hydrolyze membrane phospholipids in hormone-producing cells.
C) hydrolyze triacylglycerols stored in adipose tissue.
D) synthesize lipids in adipose tissue.
E) synthesize triacylglycerols in the liver. ✔✔ANSWER✔✔C) hydrolyze
triacylglycerols stored in adipose tissue.
What is the correct order of function of the following enzymes of beta-oxidation?
1. Oxidation (beta-Hydroxyacyl-CoA dehydrogenase)
2. Thiolytic cleavage (Thiolase)
3. Hydration (Enoyl-CoA hydratase)
4. Dehydrogenation (Acyl-CoA dehydrogenase)
,A) 1, 4, 3, 2
B) 4, 2, 3, 1
C) 1, 2, 3, 4
D) 4, 3, 1, 2
E) 3, 1, 4, 2 ✔✔ANSWER✔✔D) 4, 3, 1, 2
Which of the following statements apply (applies) to the beta oxidation of fatty
acids?
1. The process takes place in the cytosol of mammalian cells.
2. Carbon atoms are removed from the acyl chain one at a time.
3. Before oxidation, fatty acids must be converted to their CoA derivatives.
4. NADP+ is the electron acceptor.
5. The products of beta oxidation can directly enter the citric acid cycle for further
oxidation
A) 4 only
B) 1 and 3 only
C) 3 and 5 only
D) 1, 2, and 3
E) 1, 2, and 5 ✔✔ANSWER✔✔C) 3 and 5 only
The major site of formation of acetoacetate from fatty acids is the:
A) muscle
, B) kidney
C) intestinal mucosa
D) adipose tissue
E) liver ✔✔ANSWER✔✔E) liver
Carnitine is:
A) a 15-carbon fatty acid.
B) an essential cofactor for the citric acid cycle.
C) essential for intracellular transport of fatty acids.
D) one of the amino acids commonly found in protein.
E) present only in carnivorous animals. ✔✔ANSWER✔✔C) essential for
intracellular transport of fatty acids.
Lipoprotein lipase acts in:
A) hydrolysis of triacylglycerols of plasma lipoproteins to supply fatty acids to
various tissues
B) lipoprotein breakdown to supply needed amino acids
C) intracellular lipid breakdown of lipoproteins
D) none of the above ✔✔ANSWER✔✔A) hydrolysis of triacylglycerols of plasma
lipoproteins to supply fatty acids to various tissues
Fatty acids are activated to acyl-CoAs and the acyl group is further transferred to
carnitine because:
QUESTIONS AND ANSWERS GRADED A+
The role of hormone-sensitive triacylglycerol lipase is to:
A) hydrolyze lipids stored in the liver.
B) hydrolyze membrane phospholipids in hormone-producing cells.
C) hydrolyze triacylglycerols stored in adipose tissue.
D) synthesize lipids in adipose tissue.
E) synthesize triacylglycerols in the liver. ✔✔ANSWER✔✔C) hydrolyze
triacylglycerols stored in adipose tissue.
What is the correct order of function of the following enzymes of beta-oxidation?
1. Oxidation (beta-Hydroxyacyl-CoA dehydrogenase)
2. Thiolytic cleavage (Thiolase)
3. Hydration (Enoyl-CoA hydratase)
4. Dehydrogenation (Acyl-CoA dehydrogenase)
,A) 1, 4, 3, 2
B) 4, 2, 3, 1
C) 1, 2, 3, 4
D) 4, 3, 1, 2
E) 3, 1, 4, 2 ✔✔ANSWER✔✔D) 4, 3, 1, 2
Which of the following statements apply (applies) to the beta oxidation of fatty
acids?
1. The process takes place in the cytosol of mammalian cells.
2. Carbon atoms are removed from the acyl chain one at a time.
3. Before oxidation, fatty acids must be converted to their CoA derivatives.
4. NADP+ is the electron acceptor.
5. The products of beta oxidation can directly enter the citric acid cycle for further
oxidation
A) 4 only
B) 1 and 3 only
C) 3 and 5 only
D) 1, 2, and 3
E) 1, 2, and 5 ✔✔ANSWER✔✔C) 3 and 5 only
The major site of formation of acetoacetate from fatty acids is the:
A) muscle
, B) kidney
C) intestinal mucosa
D) adipose tissue
E) liver ✔✔ANSWER✔✔E) liver
Carnitine is:
A) a 15-carbon fatty acid.
B) an essential cofactor for the citric acid cycle.
C) essential for intracellular transport of fatty acids.
D) one of the amino acids commonly found in protein.
E) present only in carnivorous animals. ✔✔ANSWER✔✔C) essential for
intracellular transport of fatty acids.
Lipoprotein lipase acts in:
A) hydrolysis of triacylglycerols of plasma lipoproteins to supply fatty acids to
various tissues
B) lipoprotein breakdown to supply needed amino acids
C) intracellular lipid breakdown of lipoproteins
D) none of the above ✔✔ANSWER✔✔A) hydrolysis of triacylglycerols of plasma
lipoproteins to supply fatty acids to various tissues
Fatty acids are activated to acyl-CoAs and the acyl group is further transferred to
carnitine because:
