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A provider prescribes phenobarbital for pt. who has seizure disorder. The med. has a
long half-life of 4 days. How many times per day should nurse expect to give this med?
A) 1
B) 2
C) 3
D) 4 - CORRECT ANSWER-*Answer: A*
Rationale:
A) Meds with long half-lives remain at their therapeutic levels between doses for long
periods of time. Expect to give phenobarbital once a day.
B) A med the nurse gives 2x a day would have a shorter half life. An example is
vancomycin.
C) 3x a day would have shorter half-life. Example is zidovudine.
D) 4x a day would have short half-life. Example is ibuprofen.
A staff educator is reviewing medication disages and factors that influence medication
metabolism with a group of nurses at an in-service presentation. Which of the following
factors should the educator include as a reason to administer lower med dosages?
(Select all that apply.)
A) Increased renal excretion
B) Increased med-metabolizing enzymes
C) Liver failure
D) Peripheral vascular disease
, E) Concurrent use of medication the same pathway metabolizes. - CORRECT
ANSWER-*Answer: C, E*
Rationale:
- Liver failure decreases metabolism and thus increased concentration of a medication.
This requires decreasing the dosage.
- When same pathwat metabolizes two meds, they compete for metabolism, thereby
increasing the concentration of one or both meds. This requires decreasing dosage of
one or both meds.
- Increased renal excretion and increased med-metabolizing enzymes decreases
concentration of med, so you need to increase the med dosage.
- Peripheral vascular disease impairs distribution, so it requires increased dosage.
A nurse is preparing to administer eye drops to a pt. Which actions should nurse take?
(Select all that apply.)
A) Have pt lie on her side.
B) Ask pt. tp look up at ceiling.
C) Tell pt. to blink when drops enter her eye.
D) Drop med into the center of pts. conjunctival sac.
E) Instruct pt. to close her eye gently after instillation. - CORRECT ANSWER-*Answer:
B, D, E*
Rationale:
- Pt. should loop upward to keep drops from folling onto her cornea. Should drop med in
center of conjunctival sac to promote distribution. Should close her eye gently to
promote distribution of med.
- Pt. should sit or in a supine position to facilitate instillation of eye drops. Should NOT
blink so she doesnt eject eye drops. If she does blink, should repeat instillation.