BBH 451 Quiz 1 Solved 100% Correct
A drug binds to a receptor and activates the receptor. What type of drug action is this? -
ANSWER-agonism
A drug binds to the dopamine receptor at a location that is separate from where
dopamine binds. When the drug binds it causes a structural change to the receptor that
makes it more likely dopamine will bind to its binding site. The drug is a/an - ANSWER-
neuromodulator/allosteric drug
A drug is designed that inhibits the reuptake of dopamine. The effect of this drug will
generally be to : - ANSWER-increase dopamine levels in the synaptic cleft.
A drug is designed to treat anxiety. In this phase of the clinical trial process its
effectiveness is compared to alprazolam (a commonly-used treatment for anxiety
disorders) in a sample of patients who have an anxiety disorder: - ANSWER-Phase III
A drug is designed to treat anxiety. In this phase of the clinical trial process, its
effectiveness is measured by testing it against a placebo in a sample of individuals who
have an anxiety disorder: - ANSWER-Phase II
After administration, it takes about 30 minutes for a drug to be fully absorbed and peak
blood concentration levels to be attained. This is a description of the drug's: - ANSWER-
Pharmacokinetics
During a job interview you are very nervous, which causes your heart beat to increase
significantly. Which part of the nervous system is primarily responsible for this? -
ANSWER-Autonomic nervous system, sympathetic division.
During pregnancy, the enzyme that metabolizes caffeine (CYP1A2) becomes less
effective. If this enzyme is less efficient at metabolizing caffeine during pregnancy, what
is likely to happen to the half-life of caffeine for a pregnant woman? - ANSWER-it would
increase
If a patient takes a drug that causes high levels of serotonin and excessive activity at
the serotonin receptor, which of the following is most likely to happen? - ANSWER-
down-regulation of the serotonin receptor.
If someone has a genotype that causes them to metabolize a drug more quickly, are
they more or less likely to experience negative side effects from the drug than someone
who does not metabolize the drug very quickly? - ANSWER-less likely
In 2010, the FDA required a black box warning be put on clopidogrel (Plavix) because: -
ANSWER-In some individuals, the drug was not properly activated, increasing the risk
of cardiovascular events like heart attack.
A drug binds to a receptor and activates the receptor. What type of drug action is this? -
ANSWER-agonism
A drug binds to the dopamine receptor at a location that is separate from where
dopamine binds. When the drug binds it causes a structural change to the receptor that
makes it more likely dopamine will bind to its binding site. The drug is a/an - ANSWER-
neuromodulator/allosteric drug
A drug is designed that inhibits the reuptake of dopamine. The effect of this drug will
generally be to : - ANSWER-increase dopamine levels in the synaptic cleft.
A drug is designed to treat anxiety. In this phase of the clinical trial process its
effectiveness is compared to alprazolam (a commonly-used treatment for anxiety
disorders) in a sample of patients who have an anxiety disorder: - ANSWER-Phase III
A drug is designed to treat anxiety. In this phase of the clinical trial process, its
effectiveness is measured by testing it against a placebo in a sample of individuals who
have an anxiety disorder: - ANSWER-Phase II
After administration, it takes about 30 minutes for a drug to be fully absorbed and peak
blood concentration levels to be attained. This is a description of the drug's: - ANSWER-
Pharmacokinetics
During a job interview you are very nervous, which causes your heart beat to increase
significantly. Which part of the nervous system is primarily responsible for this? -
ANSWER-Autonomic nervous system, sympathetic division.
During pregnancy, the enzyme that metabolizes caffeine (CYP1A2) becomes less
effective. If this enzyme is less efficient at metabolizing caffeine during pregnancy, what
is likely to happen to the half-life of caffeine for a pregnant woman? - ANSWER-it would
increase
If a patient takes a drug that causes high levels of serotonin and excessive activity at
the serotonin receptor, which of the following is most likely to happen? - ANSWER-
down-regulation of the serotonin receptor.
If someone has a genotype that causes them to metabolize a drug more quickly, are
they more or less likely to experience negative side effects from the drug than someone
who does not metabolize the drug very quickly? - ANSWER-less likely
In 2010, the FDA required a black box warning be put on clopidogrel (Plavix) because: -
ANSWER-In some individuals, the drug was not properly activated, increasing the risk
of cardiovascular events like heart attack.
