BIOC 385 Exam 2 (Summer) || with 100% Error-free
Solutions.
Which one of the following is involved in the breakdown of glycogen? correct answers inorganic
phosphate
Which enzyme catalyzes the formation of alpha(1,6) linkages during glycogen synthesis? correct
answers branching enzyme
The activation of glycogen phosphorylase will lead to a(n) ____ in blood glucose concentrations
and is stimulated by the hormone _____. correct answers increase; glucagon
Because muscles lack receptors for glucagon, what hormone activates muscle glycogen
phosphorylase? correct answers epinephrine
Chylomicrons contain a monolayer on the outside of the particle consisting of ___________.
correct answers phospholipids and cholesterol
The lipase-mediated release of fatty acids can always be expected to occur when a person is
___________ and ___________. (Choose the best two answers) correct answers running from a
bear, hungry after school
In comparison with glycerophospholipids, the structure of cerebrosides contains ________ .
correct answers sphingosine
Tay-Sachs disease, Fabry disease, and Niemann-Pick disease are all symptomatic because of
___________ . correct answers defects in sphingolipid metabolism
A patient is having problems regulating blood pressure and has poor kidney function. Which
steroid could be responsible for this? correct answers aldosterone
Inhibition of the COX-1 enzyme results in correct answers reduced mucin, secretion in the
stomach
The enzyme ___________ primes fatty acids in the cytosol so they can be degraded in the
mitochondrial matrix. The enzyme ____________ catalyzes the modification of fatty acyl-CoA
derivatives so they can be transported into the mitochondrial matrix. The enzyme _________
generates palmitate from malonyl-CoA. Choose the best answer below. correct answers fatty
acyl-CoA synthetase; carnitine acyltransferase I; fatty acid synthase
How many moles of acetyl-CoA, FADH2 and NADH are generated by beta-oxidation of one
mole of the fatty acid myristate? correct answers 7 acetyle CoA, 6 NADH, 6 FADH2
What molecule is the odd chain fatty acid product propionyl-CoA converted into? correct
answers succinyl CoA
, Which of the following are ketone bodies? correct answers hydroxybutyrate, acetoacetate
What cofactor, common to carboxylase enzymes, is used by acetyl-CoA carboxylase? correct
answers Biotin
What are the different roles played the acyl carrier protein (ACP) and the ketoacyl synthase (KS)
domain during fatty acid synthesis? correct answers The ACP carries the growing fatty acid
chain more than the KS domain.
Which step is required for the synthesis of phosphatidylethanolamine? correct answers
phosphatidylserine is decarboxylated
Which of the following causes inhibition of fatty acid synthesis? correct answers increased
AMP-activated protein kinase activity
Which enzyme catalyzes the rate-limiting step of cholesterol synthesis? correct answers (HMG-
CoA) reductase
Which one of the following lipoproteins functions to transport cholesterol from the peripheral
tissues to the liver? correct answers HDL
What are the four key enzymes in nitrogen fixation and assimilation in plants and bacteria?
correct answers nitrogenase complex, glutamine synthetase, plutamate synthase, glutamata
dehydrogenase
Which of the following is the correct net reaction for the combined reaction of glutamine
synthetase and glutamate synthase? correct answers ketoglutarate + NH4++ ATP + NADH +
H+NAD++ ADP + Pi+ glutamate
What is a Benefit, and what is a Risk, of using a COX-2 selective inhibitor to treat
inflammation?
Exam 2 correct answers Benefit: decreased inflammation; Risk: increased cardiovascular
problems
How is glycogen phosphorylase allosterically activated in muscle cells?
Exam 2 correct answers Glycogen phosphorylase is shifted to R state by binding of AMP
What are the total number of moles of Acetyl CoA, NADH, and FADH2 resulting from the
complete oxidation of one mole of a fatty acid with the molecular formula C18H35O2 , and what
is its common name?
Exam 2 correct answers 9 Acetyl CoA, 8 NADH, 8 FADH2; stearate
How would you describe your liver glycogen synthase after 24 hours without food with regard
to: a) its R/T conformational equilibrium, b) its enzymatic activity, and c) its phosphorylation
state?
Solutions.
Which one of the following is involved in the breakdown of glycogen? correct answers inorganic
phosphate
Which enzyme catalyzes the formation of alpha(1,6) linkages during glycogen synthesis? correct
answers branching enzyme
The activation of glycogen phosphorylase will lead to a(n) ____ in blood glucose concentrations
and is stimulated by the hormone _____. correct answers increase; glucagon
Because muscles lack receptors for glucagon, what hormone activates muscle glycogen
phosphorylase? correct answers epinephrine
Chylomicrons contain a monolayer on the outside of the particle consisting of ___________.
correct answers phospholipids and cholesterol
The lipase-mediated release of fatty acids can always be expected to occur when a person is
___________ and ___________. (Choose the best two answers) correct answers running from a
bear, hungry after school
In comparison with glycerophospholipids, the structure of cerebrosides contains ________ .
correct answers sphingosine
Tay-Sachs disease, Fabry disease, and Niemann-Pick disease are all symptomatic because of
___________ . correct answers defects in sphingolipid metabolism
A patient is having problems regulating blood pressure and has poor kidney function. Which
steroid could be responsible for this? correct answers aldosterone
Inhibition of the COX-1 enzyme results in correct answers reduced mucin, secretion in the
stomach
The enzyme ___________ primes fatty acids in the cytosol so they can be degraded in the
mitochondrial matrix. The enzyme ____________ catalyzes the modification of fatty acyl-CoA
derivatives so they can be transported into the mitochondrial matrix. The enzyme _________
generates palmitate from malonyl-CoA. Choose the best answer below. correct answers fatty
acyl-CoA synthetase; carnitine acyltransferase I; fatty acid synthase
How many moles of acetyl-CoA, FADH2 and NADH are generated by beta-oxidation of one
mole of the fatty acid myristate? correct answers 7 acetyle CoA, 6 NADH, 6 FADH2
What molecule is the odd chain fatty acid product propionyl-CoA converted into? correct
answers succinyl CoA
, Which of the following are ketone bodies? correct answers hydroxybutyrate, acetoacetate
What cofactor, common to carboxylase enzymes, is used by acetyl-CoA carboxylase? correct
answers Biotin
What are the different roles played the acyl carrier protein (ACP) and the ketoacyl synthase (KS)
domain during fatty acid synthesis? correct answers The ACP carries the growing fatty acid
chain more than the KS domain.
Which step is required for the synthesis of phosphatidylethanolamine? correct answers
phosphatidylserine is decarboxylated
Which of the following causes inhibition of fatty acid synthesis? correct answers increased
AMP-activated protein kinase activity
Which enzyme catalyzes the rate-limiting step of cholesterol synthesis? correct answers (HMG-
CoA) reductase
Which one of the following lipoproteins functions to transport cholesterol from the peripheral
tissues to the liver? correct answers HDL
What are the four key enzymes in nitrogen fixation and assimilation in plants and bacteria?
correct answers nitrogenase complex, glutamine synthetase, plutamate synthase, glutamata
dehydrogenase
Which of the following is the correct net reaction for the combined reaction of glutamine
synthetase and glutamate synthase? correct answers ketoglutarate + NH4++ ATP + NADH +
H+NAD++ ADP + Pi+ glutamate
What is a Benefit, and what is a Risk, of using a COX-2 selective inhibitor to treat
inflammation?
Exam 2 correct answers Benefit: decreased inflammation; Risk: increased cardiovascular
problems
How is glycogen phosphorylase allosterically activated in muscle cells?
Exam 2 correct answers Glycogen phosphorylase is shifted to R state by binding of AMP
What are the total number of moles of Acetyl CoA, NADH, and FADH2 resulting from the
complete oxidation of one mole of a fatty acid with the molecular formula C18H35O2 , and what
is its common name?
Exam 2 correct answers 9 Acetyl CoA, 8 NADH, 8 FADH2; stearate
How would you describe your liver glycogen synthase after 24 hours without food with regard
to: a) its R/T conformational equilibrium, b) its enzymatic activity, and c) its phosphorylation
state?
