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A sixty-six-year-old male was prescribed phenelzine (Nardil) while in an acute psychiatric unit for
recalcitrant depression. The nurse practitioner managing his primary healthcare needs to understand the
following regarding phenelzine and other monoamine oxidase inhibitors (MAOIs):
A. He should not be prescribed any serotonergic drug such as sumatriptan (Imitrex).
B. MAOIs interact with many common foods, including yogurt, sour cream, and soy sauce.
C. Symptoms of hypertensive crisis (headache, tachycardia, sweating, etc.) require immediate treatment.
D. All the above options are correct.
- Answer -D. All the above options are correct.
An appropriate first-line drug for the treatment of depression with fatigue and low energy would be:
A. Venlafaxine (Effexor)
B. Escitalopram (Lexapro)
C. Buspirone (Buspar)
D. Amitriptyline (Elavil)
- Answer -A. Venlafaxine (Effexor)
Cara is taking levetiracetam (Keppra) to treat seizures. Routine education for levetiracetam includes
reminding her:
A. To not abruptly discontinue levetiracetam due to the risk of withdrawal seizures
B. To wear a sunscreen due to photosensitivity from levetiracetam
C. To get an annual eye exam while on levetiracetam
D. To report weight loss if it occurs
- Answer -A. To not abruptly discontinue levetiracetam due to the risk of withdrawal seizures
Cecilia presents with depression associated with complaints of fatigue, sleeping all the time, and lack of
motivation. An appropriate initial antidepressant for her would be:
, A. Fluoxetine (Prozac)
B. Paroxetine (Paxil)
C. Amitriptyline (Elavil)
D. Duloxetine (Cymbalta)
- Answer -D. Duloxetine (Cymbalta)
Cynthia is taking valproate (Depakote) for seizures and would like to get pregnant. What advice would
you give her?
A. Valproate is safe during all trimesters of pregnancy.
B. She can get pregnant while taking valproate, but she should take adequate folic acid.
C. Valproate is not safe at any time during pregnancy.
D. Valproate is a known teratogen but may be taken after the first trimester if necessary.
- Answer -D. Valproate is a known teratogen but may be taken after the first trimester if necessary.
In choosing a benzodiazepam to treat anxiety, the prescriber needs to be aware of the possibility of
dependence. The benzodiazepam with the greatest likelihood of rapidly developing dependence is:
A. Chlordiazepoxide (Librium)
B. Clonazepam (Klonopin)
C. Alprazolam (Xanax)
D. Oxazepam (Serax)
- Answer -C. Alprazolam (Xanax)
Jack, eight years old, has attention deficit disorder (ADD) and is prescribed methylphenidate (Ritalin). He
and his parents should be educated about the side effects of methylphenidate, which are:
A. Slurred speech and insomnia
B. Bradycardia and confusion
C. Dizziness and orthostatic hypotension
D. Insomnia and decreased appetite - Answer -D. Insomnia and decreased appetite