SBB study guide questions and Answers
Exam with A+ Graded Results
What enzyme may be useful in distinguishing anti-Ge2 from anti-Ge3? - CORRECT
ANSWER-Papain (Anti-Ge2 will not react)
The beta 1-3 linkage between galactose and N-actylglucosamine is found in: -
CORRECT ANSWER-Secretions
Which of the following represents the Type II chain? - CORRECT ANSWER-Beta 1-4
linkage between galactose and N acetyl glucosamine
Rank the order of decreasing H concentration on RBCs - CORRECT ANSWER-
0>A2>B>A2B>A1>A1B
All of the following are genotypes for the A1 phenotype except:
1. A1/A1
2. A1/A2
3. A2/B
4. A1/O - CORRECT ANSWER-A2/B
The ABO genes are located on which chromosome? - CORRECT ANSWER-9
Which glycosyltransferase is needed before A and B antigens are formed? - CORRECT
ANSWER-L-fucosyltransferase
What is the typical reaction of the A3 subgroup? - CORRECT ANSWER-mixed field
reaction with Anti-A and Anti-A,B
What is the typical reaction of the Ael subgroup? - CORRECT ANSWER-Positive
reaction with anti-H
What clinical condition may yield positive reactions with Anti-A, negative with Anti-B,
negative with A1 and B cells. - CORRECT ANSWER-Hypogammaglobulinemia
What differentiates a Bombay anti-H from an anti-H cold agglutin? - CORRECT
ANSWER-Reactivity at body temperature
The is antigen is associated with linear carbohydrate chains? - CORRECT ANSWER-i
antigen
, The following reactions are found on a 35 yr old male. Anti-A 4+, Anti-B 0, Anti-A,B-4+,
A1 cells 3+, B cells 4+, O cells 3+. How could these be explained? - CORRECT
ANSWER-Anti-M in plasma
Anti-IH would react best with which RBC? - CORRECT ANSWER-O
The acquired B phenomenon is only found in which ABO group? - CORRECT
ANSWER-A
Which of the following is true about the A2 subgroup?
1. 1-8% of persons will product anti-A1
2. Anti-A1 does not react with A2 RBCs
3. Anti-A2 is formed
4. Two of the above - CORRECT ANSWER-Two of the above (1-8% of persons will
product anti-A1 and Anti-A1 does not react with A2 RBC )
Anti-Lu3 is associated with: - CORRECT ANSWER-Recessive type Lu(a-b-)
The dominant Lu(a-b-) type is associated with what gene? - CORRECT ANSWER-
In(Lu)
What substance could be used to rule out anti-E in the presence of anti-Lub? -
CORRECT ANSWER-DTT
Which pair of alleles is out of place?
1. Lu8/Lu14
2. Lu8/Lu10
3.Lu6/Lu9
4. Aua/Aub - CORRECT ANSWER-Lu8/Lu10
Persons who are group B are more common among which population? - CORRECT
ANSWER-Black/Asian
Red cells that lack glycophrin A also lack: - CORRECT ANSWER-Ena antigens
Anti-ENKT reacts with which RBCs? - CORRECT ANSWER-ENaFS
What is a lectin? - CORRECT ANSWER-Seed extracts that agglutinate human cells
with moderate specificity
All of the following are representative of Lewis antibodies, except?
1. They can be neutralized by Lewis substance
2. They occur frequently in pregnant women
3. They are destroyed by enzymes
4. They are enhanced by enzymes - CORRECT ANSWER-They are destroyed by
enzymes
Exam with A+ Graded Results
What enzyme may be useful in distinguishing anti-Ge2 from anti-Ge3? - CORRECT
ANSWER-Papain (Anti-Ge2 will not react)
The beta 1-3 linkage between galactose and N-actylglucosamine is found in: -
CORRECT ANSWER-Secretions
Which of the following represents the Type II chain? - CORRECT ANSWER-Beta 1-4
linkage between galactose and N acetyl glucosamine
Rank the order of decreasing H concentration on RBCs - CORRECT ANSWER-
0>A2>B>A2B>A1>A1B
All of the following are genotypes for the A1 phenotype except:
1. A1/A1
2. A1/A2
3. A2/B
4. A1/O - CORRECT ANSWER-A2/B
The ABO genes are located on which chromosome? - CORRECT ANSWER-9
Which glycosyltransferase is needed before A and B antigens are formed? - CORRECT
ANSWER-L-fucosyltransferase
What is the typical reaction of the A3 subgroup? - CORRECT ANSWER-mixed field
reaction with Anti-A and Anti-A,B
What is the typical reaction of the Ael subgroup? - CORRECT ANSWER-Positive
reaction with anti-H
What clinical condition may yield positive reactions with Anti-A, negative with Anti-B,
negative with A1 and B cells. - CORRECT ANSWER-Hypogammaglobulinemia
What differentiates a Bombay anti-H from an anti-H cold agglutin? - CORRECT
ANSWER-Reactivity at body temperature
The is antigen is associated with linear carbohydrate chains? - CORRECT ANSWER-i
antigen
, The following reactions are found on a 35 yr old male. Anti-A 4+, Anti-B 0, Anti-A,B-4+,
A1 cells 3+, B cells 4+, O cells 3+. How could these be explained? - CORRECT
ANSWER-Anti-M in plasma
Anti-IH would react best with which RBC? - CORRECT ANSWER-O
The acquired B phenomenon is only found in which ABO group? - CORRECT
ANSWER-A
Which of the following is true about the A2 subgroup?
1. 1-8% of persons will product anti-A1
2. Anti-A1 does not react with A2 RBCs
3. Anti-A2 is formed
4. Two of the above - CORRECT ANSWER-Two of the above (1-8% of persons will
product anti-A1 and Anti-A1 does not react with A2 RBC )
Anti-Lu3 is associated with: - CORRECT ANSWER-Recessive type Lu(a-b-)
The dominant Lu(a-b-) type is associated with what gene? - CORRECT ANSWER-
In(Lu)
What substance could be used to rule out anti-E in the presence of anti-Lub? -
CORRECT ANSWER-DTT
Which pair of alleles is out of place?
1. Lu8/Lu14
2. Lu8/Lu10
3.Lu6/Lu9
4. Aua/Aub - CORRECT ANSWER-Lu8/Lu10
Persons who are group B are more common among which population? - CORRECT
ANSWER-Black/Asian
Red cells that lack glycophrin A also lack: - CORRECT ANSWER-Ena antigens
Anti-ENKT reacts with which RBCs? - CORRECT ANSWER-ENaFS
What is a lectin? - CORRECT ANSWER-Seed extracts that agglutinate human cells
with moderate specificity
All of the following are representative of Lewis antibodies, except?
1. They can be neutralized by Lewis substance
2. They occur frequently in pregnant women
3. They are destroyed by enzymes
4. They are enhanced by enzymes - CORRECT ANSWER-They are destroyed by
enzymes
