Questions and Answers
Hep-B Testing - CORRECT ANSWER-HBsAg, Anti-HBc, HBV-DNA
Hep-C Testing - CORRECT ANSWER-Anti-HCV, HCV RNA
HBsAG - CORRECT ANSWER-Appears @ 4 weeks after exposure- drops below
detectable level at 24 weeks
HBsAG detectable after 24 weeks - CORRECT ANSWER-Chronic Carrier
HBeAG - CORRECT ANSWER-envelope Antigen
means that the infection is ACTIVE and REPLICATING
*you are extremely infectious here*
anti-HBc - CORRECT ANSWER-appears about 6 weeks after exposure IgM first then
igG
alone suggests past infection
Anti-HBs - CORRECT ANSWER-detectable 32 weeks after exposure- Can be due to
HEPB vaccine
HIV Testing - CORRECT ANSWER-anti-HIV 1/2, HIV-1 RNA
HIV Donor Screening - CORRECT ANSWER-Screen with DHQ: sexual contact, money
or drugs for sex, male/male sex
Aids is to HIV as - CORRECT ANSWER-ATL is to HTLV
HTLV Testing - CORRECT ANSWER-Anti-HTLV 1/2
West Nile Virus Testing - CORRECT ANSWER-WNV RNA
West Nile Virus - CORRECT ANSWER-Flavivirus sp.
Incubation 3-14 days
Mosquito Bite
CHAGAs - CORRECT ANSWER-Typanosoma cruzi
Ruduvid bug
Endemic in Mexico, SA, CA
,CHAGAS Testing - CORRECT ANSWER-Anti-T.cruzi
Required once
Negative donors: no retest
Positive- deferred- components discarded
ELISA confirm RIPA
Syphilis - CORRECT ANSWER-Treponema pallidum
Sexual Contact
Syphilis Testing - CORRECT ANSWER-*Serologic Syphilis Test
Treponemal-Detect abs to T. pallidum
Non-treponemal- Detects abs to hapten cardiolipin
Every donor each donation
RPR
Zika - CORRECT ANSWER-Zika Favivirus
Transmitted by Ades Mosquitos
Zika Testing - CORRECT ANSWER-Zika RNA
Babesia - CORRECT ANSWER-Babsiosis
Babesia microti
deer tick
Northeast-Midatlantic
Babesia Testing - CORRECT ANSWER-Babesia NAT
Confirmed to B microti endemic states
Malaria - CORRECT ANSWER-P. vivax, P. falciparum, P. malaria, P. ovale
Mostquito bite
No screen available
Malaria Deferral - CORRECT ANSWER-1 Year- tranvel to endemic area
3 year- lived in endemic area or recovery of disease
Crutzfeldt-Jakob Disease - CORRECT ANSWER-Spongiform encephalopathies
prion in brain matter
Classical- injection/infected tissue
Variant-Transfusion
NO SCREENING
Max Blood volume to be collected - CORRECT ANSWER-1kg=2.2lbs
Donor weight x 1 kg/ 2.2lbs= ?
? x 10.5 mL/kg= ?? mL
, 2 week deferral (injection) - CORRECT ANSWER-Measles
Mumps
Polio
Typhoid
Yellow Fever
4 Week Deferral (Injection) - CORRECT ANSWER-German Measles (Rubella)
Chicken Pox/Shingles (Varicella)
12 Month Deferral ( injection) - CORRECT ANSWER-most unlicensed vaccines
14-21 Days or scab off - CORRECT ANSWER-Small pox
1 year deferral - CORRECT ANSWER-Blood recipient
mucous membrane exposure to blood
nonsterile skin penetration
sexual contact HepB, HepC, HIV
HepB vaccine
Incarceration > 72 hours
Donor Reactions - CORRECT ANSWER-Hematoma
Vasovagal reaction
Fatigue
Local Nerve Injury
Whole Blood Donation - CORRECT ANSWER-8 weeks
Double-Red - CORRECT ANSWER-16 weeks
Plasmapheresis - CORRECT ANSWER-4 weeks
Temporary Deferral - CORRECT ANSWER-Donor is unable to donate for a LIMITED
period of time
Indefinite Deferral - CORRECT ANSWER-Donor is unable to donate for an
UNSPECIFIED period of time
*donor lived in England for a year in 1989
Permanent Deferral - CORRECT ANSWER-donor will never be eligible to donate blood
for someone else
Resident Deferral - CORRECT ANSWER-Some residents of endemic areas are
deferred
Traveler Deferral - CORRECT ANSWER-some travelers visiting certain areas will be
deferred