General Pathology - Final Exam (ALL
QUESTIONS) with Correct Answers
In the remodeling phase what type of collagen is replaced? - Answer-Type 3
Which phase of wound healing is associated with the intermolecular cross-linking of
collagen? - Answer-Remodeling phase
Vascular maturation is associated with? - Answer-Increased levels of angiopoietins
All are acute phase proteins except - Answer-Plasminogen
Angiogenesis is a process that involves several signaling pathways. They include the
following except: - Answer-Kinin signaling
The remodeling phase of wound healing by primary intention includes all of the following
except: - Answer-Complete by 3 months in healthy individuals
When macrophages enter particular organs they acquire new names: - Answer-TRUE
Most inflammatory activity takes places at the post capillary venule because of the
following characteristics except: - Answer-No surrounding basal lamina pericytes
All are major components of acute inflammation except - Answer-Fibroblast migration
and deposition of collagen tumor
A critical function of inflammation is the delivery of WBC to the injury site. This process
is called transmigration. - Answer-FALSE
A 17 year old male suffers from acute viral hepatitis. Blood tests reveal elevated liver
enzymes (AST and ALT). The most likely cause of these elevated enzyme levels is
related to which of the following changes in his hepatocytes? - Answer-Cell lysis
Reversible cell injury feature includes the following except? - Answer-Myelin figures
A 68 year old woman suffers the rapid onset of right hemiparesis (weakness on one
side of the body) and severe aphasia (inability to speak). Two months later a CT scan of
her head reveals a large cystic area in the left parietal lobe of her brain. Which of the
following pathologic processes accounts for this CT finding? - Answer-Liquifactive
necrosis
Metabolic changes in aging include all of the following except - Answer-Decreased
nutrient uptake
, A 45 year old male suffers from acute myocardial ischemia. A biopsy of the ischemic
tissue would likely show? - Answer-Some condensation of nuclear contents
Which type of necrosis is associated with a predominance of heterolysis? - Answer-
Coagulative
A process of apoptosis executioner caspases do all of the following except - Answer-
Cleave DNA into random fragments
In an experiment, a tissue preparation is subjected to oxidant stress. There are
increased numbers of free radicals generated within the cells. Generation of which of
the following enzymes within these cells would most likely be protective? - Answer-
Glutathione peroxidase
A 53 year old man suffers a cardiac arrest and his wife calls emergency services. The
paramedics arrive a few minutes later and begin life support measures. A regular heart
rate is established after 40 minutes of resuscitative efforts as he is being transported to
the hospital. A thrombolytic agent (tPA) is administered. Which of the following cellular
processes is most likely to occur in his myocardium immediately following administration
of the tPA? - Answer-Free radical injury
All are nuclear changes in irreversible cell injury except? - Answer-Autolysis
Hyperplasia is an increase in the size of the cells and eventually an increase in the size
of the organ. - Answer-False
Identify the cytoskeletal structure composed of actin - Answer-Microfilaments
The difference between wet and dry gangrene. - Answer-Presence of infection
The cellular response to injury depends on the following except - Answer-Cellular
adaptability
A 30 year old man goes skiing, sustains a left femoral fracture. His leg is placed in a
plaster cast. After the leg has been immobilized for several weeks the diameter of the
left calf has decreased. This would be? - Answer-Atrophy
Pathology studies all of the following except? - Answer-Clinical management
Caseous necrosis has what kind of appearance? - Answer-Gross cheesy appearance
ATP depletion results in the decline in mitochondrial permeability which - Answer-
Associated with leakage of cytochrome c from the inner membrane
Which of the following processes is most likely occurring in the endometrium just before
the onset of bleeding? - Answer-Apoptosis
QUESTIONS) with Correct Answers
In the remodeling phase what type of collagen is replaced? - Answer-Type 3
Which phase of wound healing is associated with the intermolecular cross-linking of
collagen? - Answer-Remodeling phase
Vascular maturation is associated with? - Answer-Increased levels of angiopoietins
All are acute phase proteins except - Answer-Plasminogen
Angiogenesis is a process that involves several signaling pathways. They include the
following except: - Answer-Kinin signaling
The remodeling phase of wound healing by primary intention includes all of the following
except: - Answer-Complete by 3 months in healthy individuals
When macrophages enter particular organs they acquire new names: - Answer-TRUE
Most inflammatory activity takes places at the post capillary venule because of the
following characteristics except: - Answer-No surrounding basal lamina pericytes
All are major components of acute inflammation except - Answer-Fibroblast migration
and deposition of collagen tumor
A critical function of inflammation is the delivery of WBC to the injury site. This process
is called transmigration. - Answer-FALSE
A 17 year old male suffers from acute viral hepatitis. Blood tests reveal elevated liver
enzymes (AST and ALT). The most likely cause of these elevated enzyme levels is
related to which of the following changes in his hepatocytes? - Answer-Cell lysis
Reversible cell injury feature includes the following except? - Answer-Myelin figures
A 68 year old woman suffers the rapid onset of right hemiparesis (weakness on one
side of the body) and severe aphasia (inability to speak). Two months later a CT scan of
her head reveals a large cystic area in the left parietal lobe of her brain. Which of the
following pathologic processes accounts for this CT finding? - Answer-Liquifactive
necrosis
Metabolic changes in aging include all of the following except - Answer-Decreased
nutrient uptake
, A 45 year old male suffers from acute myocardial ischemia. A biopsy of the ischemic
tissue would likely show? - Answer-Some condensation of nuclear contents
Which type of necrosis is associated with a predominance of heterolysis? - Answer-
Coagulative
A process of apoptosis executioner caspases do all of the following except - Answer-
Cleave DNA into random fragments
In an experiment, a tissue preparation is subjected to oxidant stress. There are
increased numbers of free radicals generated within the cells. Generation of which of
the following enzymes within these cells would most likely be protective? - Answer-
Glutathione peroxidase
A 53 year old man suffers a cardiac arrest and his wife calls emergency services. The
paramedics arrive a few minutes later and begin life support measures. A regular heart
rate is established after 40 minutes of resuscitative efforts as he is being transported to
the hospital. A thrombolytic agent (tPA) is administered. Which of the following cellular
processes is most likely to occur in his myocardium immediately following administration
of the tPA? - Answer-Free radical injury
All are nuclear changes in irreversible cell injury except? - Answer-Autolysis
Hyperplasia is an increase in the size of the cells and eventually an increase in the size
of the organ. - Answer-False
Identify the cytoskeletal structure composed of actin - Answer-Microfilaments
The difference between wet and dry gangrene. - Answer-Presence of infection
The cellular response to injury depends on the following except - Answer-Cellular
adaptability
A 30 year old man goes skiing, sustains a left femoral fracture. His leg is placed in a
plaster cast. After the leg has been immobilized for several weeks the diameter of the
left calf has decreased. This would be? - Answer-Atrophy
Pathology studies all of the following except? - Answer-Clinical management
Caseous necrosis has what kind of appearance? - Answer-Gross cheesy appearance
ATP depletion results in the decline in mitochondrial permeability which - Answer-
Associated with leakage of cytochrome c from the inner membrane
Which of the following processes is most likely occurring in the endometrium just before
the onset of bleeding? - Answer-Apoptosis
