SBB Review 255 Questions with Correct Answers

SBB Review 255 Questions with Correct
Answers
Band 3 - ✅✅✅macro complex of proteins including:
-Rh
-Rag
-LW (ICAM-4)
-GPA
-GPB
-CD47


ATP source for RBCs - ✅✅✅90% from Glycolysis (Embden-
Meyerhoff pathway)
10% from pentose phosphate pathway


Met hemoglobin Reeducates Pathway - ✅✅✅necessary to maintain
home iron in ferrous (Fe2+) state
Deficiency causes accumulation of met hemoglobin, nonfunctional from
of Hob


Lumbering Rappaport Shunt - ✅✅✅permits accumulation of 2, 3-
DPG



P a g e 1 | 62

,"Tense form" of Hob - ✅✅✅DEOXYGENATED
Widening of beta-chain
Lower affinity for O2
Expels 2, 3-DPG


"Relaxed form" of Hob - ✅✅✅OXYGENATED
Beta-chain pulled together
Higher affinity for O2
Expels 2, 3-DPG


"Shift Right" - ✅✅✅higher P50 value
Decreased pH (increased H+ ion), acidosis
Increased 2, 3-DPG
Higher temperature
High pCO2


Seen in compensated anemia


"Shift Left" - ✅✅✅lower P50 value
Increased pH (decreased H+ ion), alkalosis
Decreased 2, 3-DPG
Lower temperatures
P a g e 2 | 62

,Low pCO2


Seen in storage of RBC


Type 2 precursor - ✅✅✅Gal-Glena
B1-4


Type 1 precursor - ✅✅✅Gal-Glena
B1-3


Secreted (Se, Le)


Type 2 H antigen transferees & Sugar - ✅✅✅FUT-1


Alpha-2-L-fucosyltransferase


Fructose alpha1-2


An antigen transferees & sugar - ✅✅✅D-galactosaminetrasferase


N-acetylgalactosamine alpha1-3


P a g e 3 | 62

, B antigen transferees & sugar - ✅✅✅D-galacotsyltransferase


GA lactose alpha1-3


Ax subgroup - ✅✅✅weakly positive anti-A
Weakly positive anti-A, B


Am subgroup - ✅✅✅Negative anti-A
Secretes A & H


Ale subgroup - ✅✅✅Negative anti-A
Secretes H only


Highest expression of H
Lowest expression of H - ✅✅✅O>A2>B>A2B>A1>A1B> H deficient


Lewis transferees & Sugar - ✅✅✅FUT-3


Fructose alpha1-4


Type 1 H antigen transferees & sugar - ✅✅✅FUT-2

P a g e 4 | 62