A patient gives a history of 3 years of daily opioid misuse and asks to be started on buprenorphine.
Which of the following should be completed as part of the determination regarding whether to
prescribe this medication:
A. Medical, psychiatric and substance abuse history
B. Urine toxicology screen
C. Physical examination
D. Check state prescription drug monitoring program if available
E. A, B, C and D - -B. Assure the patient your objective is concern for his/her health
-A patient in your treatment program, who has been doing very well for months, provides a urine that is
below body temperature. You suspect this is a tampered urine. Which of the following is the best
response when meeting with the patient?
A. Assume that there is a logical explanation for the cold temperature and accept the urine. The patient
has been very stable and will let you know if they relapsed.
B. Inform patient "Your urine is cold so I cannot accept it today. Tampering with urine screens is a
violation of our treatment agreement. Per protocol, you will be discharged from the program, but are
welcome back after completing detox."
C. Inform patient "The urine you provided today is below body temp. I am concerned that this is a
tampered urine. I will need another urine sample today, but I hope you know that if you are struggling, it
is better to let your treatment team know so that we can help you. So are ther - -C. Inform patient "The
urine you provided today is below body temp. I am concerned that this is a tampered urine. I will need
another urine sample today, but I hope you know that if you are struggling, it is better to let your
treatment team know so that we can help you. So are there any issues we need to address? Any recent
substance use?"
-A patient with polysubstance dependence (including opioid addiction) and HCV infection with mild
fibrosis prescribed buprenorphine/naloxone is found non-responsive and dies several hours after being
brought to the ED. Blood levels of buprenorphine are consistent with the prescribed dose. Which of the
following is the most likely explanation for the death:
A. Liver impairment resulted in buprenorphine accumulation
B. Illicit benzodiazepine use with buprenorphine/naloxone produced a toxic pharmacodynamic drug-
drug interaction
C. Buprenorphine-associated cardiac arrhythmia
D. Liver and renal impairment resulted in accumulation of buprenorphine metabolites
E. Acute liver failure related to buprenorphine/naloxone use - -
-A provider completes the required training and is eligible for the waiver to offer office-based treatment
of opioid dependence. The provider practices in a community with epidemic opioid addiction and has 38
opioid-dependent individuals who have inquired about this treatment and asked to be treated when the
provider starts the buprenorphine/naloxone practice. Which of the following is the appropriate course
of action:
A. Completion of the course and submission of the Notification of Intent form is sufficient to start
practice.
, B. The provider needs to wait up to 45 days to receive their waiver and treat up to 30 patients at one
time.
C. The provider can apply for an extended waiver to 100 upon receipt of waiver.
D. The provider may treat these patients with buprenorphine/naloxone off-label.
E. The provider may treat all of these individuals by completing an additional notification to the DEA of
the urgent need in th - -B. The provider needs to wait up to 45 days to receive their waiver and treat up
to 30 patients at one time.
-Acute withdrawal from opioid dependence using buprenorphine:
A. Does not completely suppress opioid withdrawal symptoms
B. Results in long-term opioid abstinence
C. Is unlikely to result in long term abstinence
D. Can start at any time following the use of an opioid - -C. Is unlikely to result in long term abstinence
-An opioid-dependent patient presents for buprenorphine/naloxone induction. The COWS score is 5.
Buprenorphine/naloxone 4/1 mg is given. Twenty minutes later the patient complains of nausea and
vomits as well as complaining of back and neck pain. The most likely explanation for these symptoms is:
A. Severe opioid withdrawal not relieved by buprenorphine
B. Precipitated opioid withdrawal
C. Exacerbation of co-occurring pancreatitis
D. Alcohol withdrawal
E. Naloxone absorption with increased opioid withdrawal severity - -B. Precipitated opioid withdrawal
-Because buprenorphine is a mu opioid-receptor partial agonist it is not abusable unless combined with
another central nervous system depressant.
A. True
B. False - -E. A, B, C and D
-Buprenorphine can be used for medical withdrawal from opioids.
A. True
B. False - -A. True
-Does he need additional treatment?
A. These are symptoms of prolonged opioid withdrawal and will respond to a dose increase of
buprenorphine
B. The patient is depressed and needs antidepressant treatment.
C. Guilt for past behavior is very common in early treatment and should best be handled with
psychotherapy and further involvement in self-help programs - -B. The patient is depressed and needs
antidepressant treatment.
-Does the patient require any other forms of treatment?
A. Assessment to rule out a substance-induced psychiatric disorder
B. Pharmacotherapy for depression
C. Pharmacotherapy for attention-deficit hyperactivity disorder (ADHD) - -A. Assessment to rule out a
substance-induced psychiatric disorder
-During Susie's inpatient stay she reports to the providers that she is prescribed: trazodone, clonidine,
lamictal, gabapentin, and lorazepam. Wanting to provide care for all of Susie's medical issues and avoid