NRS 272 Pharmacokinetics and Pharmacodynamics Review Questions and Correct Answers Pharmacokinetics ✅The process by which drugs are absorbed, distributed within the body, metabolized, and excreted. "What the body does to the drug" Pharmacodynamics ✅"What the drug does to the body" Mechanism of drug actions in living tissues Therapeutic effect Mechanism of action Drug -receptor relationships Enzymes Absorption ✅The transport of dissolved substances into cells. Depends on bioavailability and first pass effect -enteral route -sublingual buccal routes -parenteral route: subcutaneous, intradermal, intramuscular -topical route -transdermal route -inhaled route Enteral route ✅Drug absorbed into the systemic circulation through the oral or gastric mucosa or small intestine Oral, Sublingual, Buccal, Rectal (can also be topical) Parenteral route ✅dispensation of medications via a needle into the skin layers Intravenous Intramuscular Subcutaneous Intradermal Intraarterial Intrathecal Intraarticular What's the fastest delivery into blood circulation ✅Intravenous
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NRS 272 Pharmacokinetics and Pharmacodynamics Review Questions and Correct Answers
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Pharmacokinetics The process by which drugs are absorbed, distributed within the body, metabolized, and excreted. "What the body does to the drug" Pharmacodynamics "What the drug does to the body" Mechanism of drug actions in living tissues Therapeutic effect Mechanism of action Drug-receptor relationships Enzymes Absorption The transport of dissolved substances into cells. Depends on bioavailability and first pass effect -enteral route -sublingual buccal routes -parenteral route: subcutaneous, intradermal, intramuscular -topical route -transdermal route -inhaled route Enteral route Drug absorbed into the systemic circulation through the oral or gastric mucosa or small intestine Oral, Sublingual, Buccal, Rectal (can also be topical) Parenteral route dispensation of medications via a needle into the skin layers Intravenous Intramuscular Subcutaneous Intradermal Intraarterial Intrathecal Intraarticular What's the fastest delivery into blood circulation Intravenous
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