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NSG 552 exam II prep

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NSG 552 exam II prepSSRIs (selective serotonin reuptake inhibitors) Sertraline Fluvoxamine Fluoxetine Paroxetine Citalopram Escitalopram SNRIs (serotonin-norepinephrine reuptake inhibitors) Venlafaxine Desvenlafaxine Duloxetine Milnacipran Levomilnacipran Previous Pause Next Rewind 10 seconds Move forward 10 seconds Unmute 0:43 / 0:46 Full screen Best NFL Rookie WRs in the 2021 Season! TCAs (tricyclic antidepressants) Amitriptyline Clomipramine Doxepin Imipramine Trimipramine Desipramine Nortriptyline Protriptyline Maprotiline Amoxapine MAOIs (monoamine oxidase inhibitors) Selegiline Moclobemide Tranylcypromine Isocarboxazid Phenelzine Atypical Antidepressants Bupropion Mirtazapine Agomelatine Serotonin Modulators Nefazodone Trazodone Vilazodone Vortioxetine Typical Antipsychotics A class of older drugs to treat schizophrenia and related psychotic disorders primarily by reducing excess levels of dopamine in the brain. Atypical Antidepressants miscellaneous group of drugs with antidepressant effects but only mild side effects Benzodiazepines MOA MOA: Potentiate effects of GABA (Remember GABA is inhibitory)→drowsiness, cognitive impairment, dampening of fear and anxiety Risk of elder patients using Benzodiazepines Increased fall risk, hip fracture risk General risk of using Benzos Potential for abuse and addiction • Patient become physical dependent and build tolerance • Can be used to treat Akathisia • Choice of BDZ depends on time of onset, duration of action and method of metabolism (OTL= Outside The Liver( Lorazepam, Oxazepam, Temazepam)= not metabolized by the liver • S/E: Anticholinergic, unusual behaviors, hallucinations, daytime drowsiness, Benzodiazepine Withdrawal = like ETOH withdrawal Insomnia • Anxiety • Hand tremors • Irritability • Anorexia • Nausea/vomiting • Autonomic hyperactivity (diaphoresis, tachycardia, HTN) • Tonic -clonic seizures = life threatening Tapering Benzos Note: Abrupt abstinence after chronic use can be life threatening. • Taper ~ 10% total dose/week • "Physical and behavioral taper" • Common strategy to convert from SA to LA to facilitate more comfortable taper Endocrine Conditions that mimic or worsen anxiety Hyperthyroidism Hypothyroidism Pheochromocytoma Cushings disease Addisons disease Menopause Cardiovascular conditions that mimic or worsen anxiety Acute coronary syndrome Arrhythmia CHF Hypertension Hypertension Mitral valve prolapse Neurological conditions that mimic or worsen anxiety Epilepsy Cerebrovascular disease Meniere's disease MS Migraines Encephalitis Early Dementia Metabolic conditions that mimic or worsen anxiety Porphyria Diabetes Pulmonary conditions that mimic or worsen anxiety Asthma COPD Pulmonary Embolism


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