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Exam (elaborations)

Maryville Pharm Exam 3 Questions and explanations with solutions

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Antigout Drugs - allopurinol (Zyloprim) colchicine (Colcyrs) febuxostat (Uloric) Allopurinol MOA - inhibit synthesis of uric acid by inhibiting xanthine oxidase conversion of hypoxanthine & xanthine to uric acid Allopurinol use - prevention of further gouty attacks (prophylaxis) manage hyperuricemia What should be monitored before starting allopurinol? - **renal fx - need renal dosing LFTs blood counts What are the side effects of allopurinol? - drowsiness and dizziness

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