Pharmacology 1 Exam #2 –Ameritech.Questions With 100% Correct Answers.

Adverse effects of Aminoglycosides - -Ototoxicity (25% of pts) -Nephrotoxicity (26% of pts, long half-life) -Intense neuromuscular blockade (pts w/ myasthenia gravis) -Neurotoxicity -Hypersensitivity Adverse effects of Antifungals - -Infusion reactions - fever, chills, rigors (sudden feeling of cold with climbing fever) -Nephrotoxicity -Hyperkalemia/Electrolyte imbalance -Bone marrow suppression -Hepatotoxicity (Ketoconazole) Adverse effects of Antiprotozoals - -Suprainfections -GI discomfort - metallic taste* -Dark urine -Neurotoxicity - numbness of extremities, seizures, ataxia (loss of full body control) -Psuedomembranous Colitis - C-DIFF Adverse effects of Antivirals - -Nephrotoxicity (Acyclovir) -Gingival Hyperplasia (Acyclovir) Adverse effects of Broad-Spectrum Antimycobacterials - -Suprainfections -Discoloration of body fluids (orange urine, sweat, tears, and saliva)* -Hepatotoxicity (jaundice, anorexia, fatigue) -Mild GI discomfort (50% of pts) -Pseudomembranous Colitis (C-DIFF)Adverse effects of Carbapenems - -Allergic reactions - dyspnea, rashes, and pruritis -Hypersensitivity -Gastrointestinal upset (nausea, vomiting, diarrhea) -Suprainfection (colitis, oral thrush, vaginal yeast infections)