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Neural Circuits Lecture 9

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These revision notes delve into the developmental programs that control brain wiring to understand the cues that trigger neurons to take the correct shape and connect with appropriate partners. My revision notes also concisely explore how understanding neural circuit assembly suggests ways of treating the many neurological and psychiatric disorders that result from mistakes in brain wiring.

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Neural Circuits NC9

Non-Associative learning

Definition of Learning and memory
 Learning
 The process of acquisition of information on consistent spatial and
temporal relationships between events in the internal and external
environment
 This process leads to a change in behavioural performance as a
result of previous experience
 Memory
 Storage of the knowledge acquired by learning
 The persistence of change in behavioural performance after
learning has been completed

There are 2 major types of memory:
 Explicit
 Declarative, conscious, facts
 Implicit
 Non-declarative, Unconscious, habituation

Non-associative learning uses reflex pathways

Non-associative learning:
 Learning that does not require linking or associating stimuli together
 It is considered the simplest type of learning and therefore a topic which
can help us gain fundamental insight into how learning occurs in neural
circuits

Types of non-associative learning
 Habituation
 A decrease in behaviour due to repeated exposure to innocuous
stimuli
 Sensitization
 An increase in behaviour due to exposure to a noxious stimulus

Habituation
 There are several well-defined behavioural examples of habituation and
sensitization, but to examine the underlying learning circuits is very
difficult in complex mammalian systems.
 Invertebrates provide an excellent opportunity to study basic forms of
cellular activity such as the Tritonia CPG, you have already heard about.
 The very first organism where simple learning paradigms were studied
on the circuit level was the Aplysia model system.

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