Module 3 nurs 5334 Questions With Correct Answers

Topical anesthesia - The ability of an anesthetic to penetrate the axon membrane is determined by 1. Molecular size 2. Lipid solubility 3. Degree of ionization at tissue ph Lidocaine - Injectable, gels Lido with epi to constrict blood flow and prolongs anesthesia and decrease risk of toxicity Mu receptors - Responses to activation of these receptors include: analgesia, respiratory depression, euphoria, sedation, and physical dependence Most important receptors for opioids because they act primarily by activating mu receptors Kappa receptors - Activation of these receptors can produce: analgesia and sedation Kappa activation my underly psychotomimetic effects seen with certain opioids Delta receptors - Generally opioids don't interact with these Pure opioid agonists - Activate mu and kappa receptors can produce analgesia, euphoria, sedation, respiratory depression, physical dependence, constipation, and other effects Morphine - Strong opioid agonist Codeine - Moderate to string opioid agonist Agonist antagonist opioid - Pentazocine, nalbuphine, butorphanol, buprenorphine When administered alone produces analgesia If admined with pure opioid agonist, can