PC707 Final Exam Ultimate Study Guide | 100% Correct Answers | Verified | Latest 2024 Version

What class of medication can cause tooth discoloration, deposits on bones, and bone growth restriction? - Tetracycline antibiotics What are the risks to a postpartum mother and newborn if the mother is an ultra-rapid metabolizer taking codeine? - opioid toxicity *in ultrarapid metabolizers, there may be an increase in morphine from codeine, resulting in opioid toxicity. Combined oral contraceptives increase blood levels of _____________________, _____________________, _______________, and ________________. - theophylline valium TCA's Lithium Grapefruit juice is a CYP450 ____________, and leads to ______________ pharmacologic effect of drugs. - inhibitor increased What electrolyte do you need to monitor while a patient is taking Drospirenone (COC)? - Potassium It also interacts with other K+ sparing drugs, causing hyperkalemia (ACEi, ARBs, K+ sparin diuretics, NSAIDs) Iron supplementation is contraindicated in whom? - children 6 years overdose is fatalWhat are the risks to a pregnant woman who takes an NSAID? (2 listed) - Hypertension bleeding at delivery What are the risks to a fetus if the mother takes an NSAID? (2 listed) - premature closure of DA may cause GI bleeds Probiotic use is contraindicated in whom? - immunocompromised individuals What fatal rhythm is the risk when taking a medication that causes a QT prolongation? - torsades T/F: A 30-year old woman with hyperlipidemia can safely continue to take her statin when pregnant. - False *Statins are teratogenic in pregnancy Excessive intake of what vitamin is teratogenic in pregnancy? - Vitamin A/Retinoic Acid What is the black box warning for fluoroquinolones? - tendon rupture fluoroquinolones should not be prescribed for patients with peripheral atherosclerotic vascular disease, HTN, Marfan's syndrome and the elderly d/t the increased risk of what? - aortic aneurysm Clarithromycin (Biaxin) should not be taken with what two HMG-CoA reductase inhibitors (statins)? - lovastatin simvastati