Quiz 1 Pharmacology 5334

Quiz 1 Pharmacology 5334 questions and answers verified Acute Bact Prostatitis Tx - Floxacins Agonist-Antagonist Opioids - -act as agonists at kappa receptors and antagonists at mu receptors -produce less analgesia than morphine and have a lower potential for abuse -there is a ceiling to respiratory depression -if given to a patient dependent on pure opioids agonists, it will precipitate withdrawal all DMARDs - suppress the immune system Allopurinol - 1st line dx for tx for chronic topaceous gout Aminoglycosides adverse effects - ototoxicity and nephrotoxicity aminoglycosides peak and trough - Peak: 30 min after IV or IM Trough: divided- before next dose, daily-1 hr before next dose (value should be low: like zero) Aminoglycosides treat - gram negative bacilli Amphotericin B BBW - infusion rxn & nephrotoxicity; only use in life threatening infection Aspirin drug interactions - Anticoagulants: Warfarin and heparin Glucocorticoids Alcohol Ibuprofen ACE inhibitors and ARBs Bacitracin and Polymyxin B treats - Topical treatment for bacterial dx bacterial vaginosis treatment - -Metronidazole -Clindamycin Bedaquiline BBW - hepatotoxicity Capreomycin Adverse Effects - nephrotoxicity and ototoxicity; BBW: disturbed balance Carbamazepine BBW - test for HLA-B 1502 in Asians; causes SJS and TEN Carbapenems - not active against MRSA Celecoxib AE - Sulfonamide (allergic reaction) *Cardiovascular thrombotic events*(due to imbalance b/t COX-1 and COX-2) *Renal impair. Celecoxib drug interactions - Warfarin May decrease diuretic effect of furosemide May decrease antihypertensive effect of ACE inhibitors May increase levels of lithium Celecoxib levels may be increased by fluconazole Cephalosporin and PCN - Cross allergy w/PCN Cephalosporin Generation 1 - -cephalexin -cephazolin -cephadoxil Chlamydia treatment for adults - azithromycin or doxycycline chlamydia treatment for children - 45 kg= erythromycin 45 kg & less than 8 y.o.= azithromycin Chloramphenicol BBW - fatal aplastic anemia Classification of drugs for Opioid receptors - Pure opioid agonist, agonist-antagonist opioids, pure opioid antagonist Cluster headache treatment - -glucocorticoids - verapamil -lithium Colchicine - -tx, reduces, and aborts attack -no longer 1st line dx Cox 2 - not for inflammation; reduce pain & fever, protects