Local & Systemic Complications of Local Anesthesia

Local & Systemic Complications of Local Anesthesia A drug overdose reaction is caused by a level of a drug in the blood that is sufficiently high to produce adverse effects in various organs and tissues of the body in which the drug exerts a clinical action. These are termed the _________ of the drug. - correct answerstarget organs A prolonged, tetanic spasm of the jaw muscles by which the normal opening of the mouth is restricted. - correct answersTrismus Allergic reactions to a drug are not ________ related - correct answersdose At blood levels of general anesthesia greater than 10 ug/ml, what will likely occur? - correct answersSeizure activity will cease amd a state of generalized CNS depression develops. Respiratory depression and arrest (apnea) are manifestations of this. In the CVS, bradycardia and cardiac arrest will most likely occur. At blood levels of local anesthesia greater than 4.5 ug/ml, what clinical manifestations will be seen? - correct answersexcitation (generalized cortical sensitivity): talkativeness, agitation, irritability At blood levels of local anesthesia greater than 7.5 ug/ml, what will likely occur?