1.Pernicious anemia: lack of intrinsic factor, decreased b12
2.Pernicious anemia s/s: beefy red tongue, fatigue, paresthesia of
hands/feet, fatigue
3.macrocytic anemias: Pernicious anemia, folate deficiency anemia
>103mm
4.causes of macrocytic anemias: liver disease, low b12 or folate,
gastrectomy, malabsorption, alcoholics
5.microcytic anemia: iron deficiency, anemia of chronic disease late
stage, lead poisoning, thalassemias,, occult blood in stool,
menorrhagia, <87mm
6.normocytic anemia: anemia of chronic disease, sickle cell, impaired
bone mar- row, hemolytic anemia, 87-103mm
7.primary storage for iron: ferritin >100 = normal
8.increased ferritin: inflammatory disease, hepatitis, CRF,
9.transferrin: regulates iron absorption and transport in body, low levels
= protein malnutrition, >200 is normal
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, 10.total iron binding capacity (TIBC): high when iron low 240-450
> 400 with iron deficiency anemia
11.Primary hypothyroidism: High TSH, low T3 and T4
12.Secondary hypothyroidism: low TSH, low T3/T4, malfunction of
pituitary
13.Hashimoto's thyroiditis: autoimmune thyroiditis, high TSH, low T3/T4
14.Myxedema: puffy face with hypothyroid
15.Grave's disease: autoimmune disorder leading to hyperthyroidism,
antibodies mimicking TSH, high T4/T3
16.Primary Hyperthyroidism: Low TSH High T3,T4
17.excessive iodine uptake: hyperthyroidism
18.first test for thyroid: TSH
19.TSH improvement after levothyroxine: 6-8 weeks
20.subclinical hypothyroid: elevated TSH, normal T4 and Free T4
21.PTU, methimazole: treat hyperthyroidism- agranulocytosis and liver
disease SE
22.prevalence of HTN after 65 years of age: higher in women
23.DBP stabilizes?: age 50 and older, SBP worsens
24.nocturnal BP: dipping at night by 15%. non-dipper = high risk for
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