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Exam (elaborations)

CCTC Exam REAL exam

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CCTC Exam REAL exam CMV IGG & IGM (-) - Not previously CMV infected CMV IgG & IgM (+) - Recent CMV infection CMV IgG (+) & IgM (-) - Past CMV infection, not recent Blood Type O - Universal Donor - Can receive subtype A2 Blood Type AB - Universal Recipient Kidney Priority Listing Criteria - 1) If candidate is prior living kidney donor 2) If there are 0 HLA-mismatches Common causes of HLA Antibody production - 1) Transfusions 2) Pregnancy 3) Previous transplants Hep C Ab - Exposure to Hepatitis C Hep B sAg - Infection with hepatitis B Hep B sAb - Immune to hepatitis B Hep B Core Antibody - Previous hepatitis B infection or exposure HLA Haplotypes - A, B, DR Rejection - Recognition step - AP Cells Rejection - Stimulation step - T-Cells Rejection - Defense step - CD8 and B Cells Immunosuppression balances 3 key factors - 1) Prevent rejection 2) Protect against infection and cancer 3) Guarantee efficacy What organ is not allocated based on urgency? - Kidney How does UNOS prioritize? - 1) Medical urgency 2) Biological matching

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