2024 Usmle Step 1 NEW UPDATE 2023 WITH QUESTIONS AND CORRECT ANSWERS |GRADED A

2024 Usmle Step 1 NEW UPDATE 2023 WITH QUESTIONS AND CORRECT ANSWERS |GRADED A often precedes squamous cell carcinoma - ANSWER- actinic keratosis primary adrenocortical deficiency - ANSWER- Addison's disease polyostotic fibrous dysplasia, precocious puberty, cafe-au-lait spots, short stature, young girls - diagnosis? - ANSWER- Albright's syndrome hereditary nephritis with nerve deafness - ANSWER- Alport's syndrome anti-basement membrane antibodies - diagnosis? - ANSWER- Goodpasture's syndrome anticentromere antibodies - diagnosis? - ANSWER- scleroderma (CREST) anti-double-stranded DNA antibodies (ANA antibodies) - diagnosis? - what hypersensitivity type? - ANSWER- SLE - type III hypersensitivity anti-epithelial cell antibodies - diagnosis? - ANSWER- pemphigus vulgaris antigliadin antibodies - diagnosis? - ANSWER- celiac disease antihistone antibodies - diagnosis? - ANSWER- drug-induced SLE anti-IgG antibodies - diagnosis? - ANSWER- rheumatoid arthritis antimitochondrial antibodies - diagnosis? - ANSWER- primary biliary cirrhosis antineutrophil antibodies - diagnosis? - ANSWER- vasculitis antiplatelet antibodies - diagnosis? - ANSWER- idiopathic thrombocytopenic purpura arachnodactyly - diagnosis? - ANSWER- Marfan's syndrome Argyll-Robertson pupil - diagnosis? - ANSWER- neurosyphilis Arnold-Chiari malformation - ANSWER- cerebellar tonsillar herniation Aschoff bodies - diagnosis? - ANSWER- rheumatic fever atrophy of the mammillary bodies - diagnosis? - ANSWER- Wernicke's encephalopathy Auer rods - diagnosis? - ANSWER- acute myelogenous leukemia (especially promyelocytic type) autosplenectomy - diagnosis? - ANSWER- sickle cell anemia Babinski's sign is associated with what? - ANSWER- UMN lesion "bamboo spine" on x-ray - ANSWER- ankylosing spondylitis basophilic stippling of RBCs - diagnosis? - ANSWER- lead poisoning defective dystrophin, less severe than Duchenne's - ANSWER- Becker's muscular dystrophy LMN CN VII palsy - ANSWER- Bell's palsy Bence Jones proteins - possible diagnoses? - in each case, what are the proteins? - ANSWER- multiple myeloma - kappa or lambda light chains Waldenstrom's macroglobulinemia - IgM IgA nephropathy - diagnosis? - ANSWER- Berger's disease Bernard-Soulier disease - what is the defect? - ANSWER- defect in platelet adhesion bilateral hilar adenopathy, uveitis - diagnosis? - ANSWER- sarcoidosis Birbeck granules on EM - diagnosis? - ANSWER- histiocytosis X (eosinophilic granuloma) bloody tap on LP - diagnosis? - ANSWER- subarachnoid hemorrhage "blue bloater" - ANSWER- chronic bronchitis blue-domed cysts - diagnosis? - ANSWER- fibrocystic change of the breast blue sclera - diagnosis? - ANSWER- osteogenesis imperfecta boot-shaped heart on x-ray - possible diagnoses? - ANSWER- tetralogy of Fallot or RVH Bouchard's nodes - diagnosis? - where are they located? - why do they occur? - ANSWER- osteoarthritis - on PIP secondary to osteophytes boutonniere deformity - diagnosis? - ANSWER- rheumatoid arthritis branching rods in oral infection - diagnosis? - ANSWER- Actinomyces israelii "brown tumor" of bone - possible diagnoses? - what causes the brown color? - ANSWER- hyperparathyroidism or osteitis fibrosa cystica (von Recklinghausen's disease) - color is due to hemorrhage in cysts X-linked agammaglobulinemia - ANSWER- Bruton's disease posthepatic venous thrombosis - diagnosis? - ANSWER- Budd-Chiari syndrome Buerger's disease - what size arteries does it affect? - ANSWER- small or mediumartery vasculitis Burkitt's lymphoma - what is the translocation? - what virus is it associated with? - appearance on histology? - ANSWER- 8:14 translocation EBV starry sky appearance Burton's lines - diagnosis? - ANSWER- lead poisoning what types of ANCA are associated with Wegener's granulomatosis and microscopic polyangiitis? - ANSWER- Wegener's - c-ANCA MPA - p-ANCA cafe-au-lait spots on skin - diagnosis? - ANSWER- neurofibromatosis calf pseudohypertrophy - diagnosis? - ANSWER- Duchenne's muscular dystrophy Call-Exner bodies - diagnosis? - ANSWER- granulosa-theca cell tumor of the ovary cardiomegaly with apical atrophy - diagnosis? - ANSWER- Chagas' disease trypanosome infection - diagnosis? - ANSWER- Chagas' disease painless chancre - diagnosis? - ANSWER- primary syphilis painful chancroid - cause? - ANSWER- Haemophilus ducreyi Charcot's triad of multiple sclerosis - ANSWER- nystagmus, intention tremor, scanning speech Charcot's triad of cholangitis - ANSWER- jaundice, RUQ pain, fever