UNE CHEM 1005: MEDICAL BIOCHEMISTRY FINAL EXAM QUESTIONS & A NSWERS 100% CORRECT!

Carnitine palmitoyl transferase - ANSWERS- transfers acyl groups from CoA to carnitine & vice versa - inhibited by malonyl-CoA ketone bodies - ANSWERS- acetoacetate, β-hydroxybutyrate, acetone - oxidized as fuel source in extreme fasting d-3-hydroxybutyrate dehydrogenase - ANSWERSinterconversion of acetoacetate and 3-hydroxybutyrate acetone - ANSWERSyielded by spontaneous decarboxylation of acetoacetate; waste product acetoacetate and 3-hydroxybutyrate - ANSWERS- ketone bodies produced during fasting - used for energy in various tissues hyperglycemia and ketogenesis - ANSWERS- occurs in fasted state - loss of insulin (type 1 diabetes) Ketogenesis - ANSWERSthe process by which excess acteyl-CoA is converted into ketone bodies products of B-oxidation of fatty acids - ANSWERS- NADH - FADH2 - acteyl-CoA regulatory step in fatty acid synthesis - ANSWERSproduction of malonyl-CoA by acetyl-CoA carboxylase acetyl-CoA carboxylase is inhibited by - ANSWERS- Palmitoyl-CoA - fatty acyl-CoA under fasted conditions cofactor of acetyl-CoA carboxylase - ANSWERSBiotin regulated step of lipogenesis - ANSWERScarboxylation of acetyl-CoA NADPH - ANSWERS- essential for fatty acid synthesis