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Pathophysiology A Practical Approach Study Guide Rated A

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Pathophysiology: A Practical Approach Study Guide Rated A+ Active transport Adaptation Allele Anaphase (Mitosis) anaplasia(an-ah-PLAY-zee-ah) Apoptosis Atrophy Autosomal dominant Autosomal recessive Autosome Benign Cancer Carcinogenesis Caseous necrosis Cell membrane chromosome Coagulative necrosis congenital Crenation curative Cytoplasm Deoxyribonucleic acid (DNA Differentiation Diffusion Dominant Dry gangrene Dysplasia Electrolyte Endocytosis Enzymes

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Pathophysiology: A Practical Approach Study
Guide Rated A+

1). Active transport

 Ans: The movement of a substance from an area of lower concentration to an area of a
higher concentration, against a concentration gradient


2). Adaptation

 Ans: Method by which cells attempt to prevent their own death from environmental
changes. They may modify their size, numbers, or types in an attempt to manage these
changes and maintain homeostasis.


3). Allele

 Ans: One gene that may have many variants, which determines a characteristic.


4). Anaphase (mitosis)

 Ans: Phase of mitosis in which chromosomes separate and move to opposite poles


5). Anaplasia(an-ah-play-zee-ah)

 Ans: The loss of cell differentiation that occurs with cancer.
ana- = not, without
-plasia = formation, growth


6). Apoptosis

 Ans: Mechanism of programmed cell death that occurs because of morphologic
changes in cells (programmed cell death)


7). Atrophy

 Ans: State that occurs because of decreased work demands on a cell. When cellular
work demands decrease, the cells decrease in size and number.




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, 8). Autosomal dominant

 Ans: Type of disorder in which a single gene mutation is passed from an affected
parent to an offspring regardless of sex. Autosomal dominant disorders occur with
homozygous and heterozygous allele pairs.


9). Autosomal recessive

 Ans: Type of disorder in which single gene mutations are passed from an affected
parent to an offspring regardless of sex but occur only in homozygous allele pairs.


10). Autosome

 Ans: A paired set of chromosomes in deoxyribonucleic acid (DNA).


11). Benign

 Ans: (mild, not cancerous)
Near-normal differentiated condition of a cell or tumor, which causes fewer problems than
an abnormal cell or tumor. Benign cells are usually encapsulated and are unable to
metastasize.


12). Cancer

 Ans: The disease state associated with uncontrolled cellular growth. Key features
include rapid, uncontrolled proliferation and a loss of differentiation.


13). Carcinogenesis

 Ans: The process by which cancer develops. It occurs in three phases: initiation,
promotion, and progression.


14). Caseous necrosis

 Ans: Type of necrosis that occurs when the necrotic cells disintegrate, but the cellular
debris remains present for months or years.


15). Cell membrane

 Ans: The semipermeable boundary containing the cell and its components.




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