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First Aid USMLE Step 1: Pharmacology (Complete study guide with answers for latest updates
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Penicillin G (IV and IM) Penicillin M (oral) - >>*MOA:* *β-lactam*: a structural analog of D-ala-D-ala (a normal component of cell walls) which binds and inactivates bacterial transpeptidases (penicillin-binding protein, PBPs) to block peptidoglycan cross linking *Clinical use:* Bactericidal for Gram-⊕ cocci/rods, Gram-⊖ cocci (Neisseria), and spirochetes Mostly used for Gram-⊕ organisms (S. pneumoniae, S. pyogenes, Actinomyces). Also used for Gram-⊖ cocci (mainly N. meningitidis) and spirochetes (namely T. pallidum). Bactericidal for Gram-⊕ cocci, Gram-⊕ rods, Gram-⊖ cocci, and spirochetes. Penicillinase sensitive. *Toxicity:* Hypersensitivity reactions (type II), hemolytic anemia
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Institution
Nursing Pharmacology
Course
Nursing pharmacology
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- Institution
- Nursing pharmacology
- Course
- Nursing pharmacology
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- Uploaded on
- March 28, 2024
- Number of pages
- 123
- Written in
- 2023/2024
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first aid usmle step 1 pharmacology complete stu
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