BioChem C785 - WGU - Module 4 - all Questions and Answers Verified and Complete

BioChem C785 - WGU - Module 4 - all Questions and Answers Verified and Complete A 2-year old boy found to have an autosomal recessive glycogen storage disease that prevents him from being able to fully metabolize glucose. On examination, he has an enlarged liver and bulky appearing muscles. Biopsy of both the liver and the muscles shoes markedly increased amounts of glycogen compared to normal - What is true? Correct Answer- Since glucose can be partially but not fully metabolized, there is an increased concentration of the intermediate compounds and this causes a shift in enzymatic reactions, favoring the production of glycogen A defect in an enzyme in the citric acid cycle causes the cycle to stop functioning. What are possible consequences? Correct Answer- decreased levels of ATP A defect occurs that prevents pyruvate from converting to lactate under anaerobic conditions - what is a possible consequence? Correct Answer- glycolysis stops because NAD+ levels are too low A molecule that assists an enzyme in driving biochemical reactions is: Correct Answercoenzyme A patient with advanced cancer has not been able to eat a full meal for the past 3 months, and his intake has gradually diminished over the last month such that his entire intake in the prior 3 days consists solely of water. What is most likely? Correct Answer- He is likely to have lost adipose tissue and muscle mass A risk factor associated with use of metformin in the treatment of diabetes is lactic acidosis. Acidosis is associated with a decrease in blood pH, due to an increase in the concentration of hydrogen ions (H+). Given this change in blood pH, hemoglobin is more likely to release oxygen. Correct Answer- True